Enhancing Effectiveness Research on Recovery Housing for Persons Prescribed Medication for Opioid Use Disorder

加强阿片类药物使用障碍处方药患者康复住房的有效性研究

• 批准号: 10590474
• 负责人: AMY Adale MERICLE
• 金额: $ 192.13万
• 依托单位: PUBLIC HEALTH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-30 至 2025-09-29
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10590474
• 关键词: Address; Advanced Development; Age; Alcohol consumption; Area; Attitude; Brain; Buprenorphine; Caring; Chronic; Clinical; Communities; Continuity of Patient Care; Criminal Justice; Cues; Dependence; Disease; Drug Prescriptions; Drug Use Disorder; Economic Burden; Effectiveness; Employment; Environment; Evidence based practice; Exposure to; FDA approved; Face; Fentanyl; Fostering; Funding; Goals; Health Services; Heroin; Housing; Human; Impairment; Individual; Infrastructure; Intervention; Lead; Life; Literature; Medical; Mentors; Methadone; Naltrexone; Nature; Opioid; Outcome; Persons; Pharmaceutical Preparations; Phase; Physiological; Pilot Projects; Play; Policies; Process; Provider; Recovery; Recovery Support; Relapse; Research; Research Methodology; Research Personnel; Resources; Risk; Role; Scientist; Seasons; Series; Services; Social isolation; Structure; Training; Unemployment; Withdrawal; addiction; base; college; community center; comorbidity; critical period; design; effectiveness research; evidence base; experience; high school; improved; innovation; member; neuronal circuitry; novel; opioid epidemic; opioid use; opioid use disorder; overdose death; overdose risk; peer; peer support; provider networks; psychologic; public health relevance; response; substance use; substance use treatment; symposium; synthetic opioid; tool; treatment services; webinar

PROJECT SUMMARY/ABSTRACT Safe and stable housing is widely recognized as critical to recovery from alcohol and drug use disorders generally, but it may be even more critical to recovery from opioid use disorders (OUD). Addiction to opioids is associated with changes in the structure and function of the brain. These changes may take months or years to resolve, all the while leaving individuals vulnerable to relapse, which is all too often deadly. It may also lead to unemployment, criminal justice involvement, and social isolation, which present additional impediments to recovery. Recovery housing can offer invaluable support in the early phases of recovery by providing structure and minimizing exposure to conditioned cues and other triggers for relapse. It can also set the stage for long- term gains by integrating residents into new peer communities that are supportive of recovery and can help as they face challenges in daily life. Unfortunately, research on the outcomes of residents in recovery from OUD, particularly those being treated with medications is limited. Further, there is literature that suggests that individuals being treated with medications for OUD (MOUD) may experience barriers to recovery housing due to negative attitudes towards MOUD and lack of recovery housing that is equipped to support persons on medication. This application seeks to enhance infrastructure to conduct effectiveness research on recovery housing for persons treated with MOUD. Specifically, it aims to: (1) Develop a network of diverse stakeholders dedicated to expanding access to recovery housing for persons prescribed MOUD and conducting research on it; (2) Increase capacity of recovery housing that is equipped to support residents who are prescribed MOUD and to participate in effectiveness research as well as researchers who are trained to conduct it; (3) Provide resources and opportunities to junior investigators and those who may be new to recovery housing research to collaborate with recovery housing researchers to expand the evidence base on recovery housing for persons treated with MOUD. To achieve these aims, the proposed team will establish an Advisory Board comprised of leading researchers and members of national treatment, recovery, and recovery housing organizations to establish a large multi-stakeholder network of providers and researchers. The team will also host a webinar series with intensive year-long tracks for recovery housing providers and researchers new to the field and foster opportunities for these researchers to network with providers and other researchers at conferences. Finally, members of the team will mentor pilot studies with junior and new recovery housing researchers to develop new tools and establish the feasibility of innovative research methods and research in novel settings to fill key gaps in the literature. Findings from these pilot studies will be disseminated to the larger multi-stakeholder network to improve practice and launch wider scale effectiveness research.

项目概要/摘要 安全稳定的住房被广泛认为对于酗酒和吸毒障碍的康复至关重要 一般来说，但它对于从阿片类药物使用障碍 (OUD) 中恢复可能更为重要。阿片类药物成瘾是 与大脑结构和功能的变化有关。这些变化可能需要数月或数年的时间才能完成 决心，同时使个人容易复发，这往往是致命的。它还可能导致 失业、刑事司法介入和社会孤立，这些都构成了额外的障碍 恢复。恢复住房可以通过提供结构在恢复的早期阶段提供宝贵的支持 尽量减少接触条件暗示和其他旧病复发的诱因。它还可以为长期奠定基础 通过将居民融入新的同侪社区来支持恢复并可以帮助 他们在日常生活中面临挑战。不幸的是，关于居民从 OUD 中恢复的结果的研究， 特别是那些正在接受药物治疗的人受到限制。此外，有文献表明 接受 OUD (MOUD) 药物治疗的个人可能会因以下原因而在康复住房方面遇到障碍： 对 MOUD 的负面态度以及缺乏能够支持人们的康复住房 药物。该应用程序旨在增强基础设施以进行恢复有效性研究 接受 MOUD 治疗的人的住房。具体而言，其目标是： (1) 发展多元化利益相关者网络 致力于扩大 MOUD 规定人员获得康复住房的机会，并开展研究 它; (2) 增加恢复住房的容量，以支持符合 MOUD 规定的居民 参与有效性研究以及受过培训的研究人员； (3) 提供 为初级研究人员和那些可能不熟悉恢复住房研究的人提供资源和机会 与康复住房研究人员合作，扩大人员康复住房的证据基础 用MOUD处理。为了实现这些目标，拟议的团队将设立一个顾问委员会，其成员包括 国民治疗、康复和康复住房组织的主要研究人员和成员 建立一个由提供者和研究人员组成的大型多利益相关者网络。该团队还将举办网络研讨会 系列为刚进入该领域和培育的康复住房提供者和研究人员提供为期一年的强化课程 这些研究人员有机会在会议上与提供者和其他研究人员建立联系。最后， 该团队的成员将指导初级和新康复住房研究人员进行试点研究，以开发新的 工具并建立创新研究方法和新环境研究的可行性，以填补关键空白 在文献中。这些试点研究的结果将传播到更大的多利益相关者网络，以 改进实践并开展更广泛的有效性研究。