Regenerative Engineering of Musculoskeletal Tissues- a Convergence Doctoral Training Program

肌肉骨骼组织再生工程-融合博士培训项目

• 批准号: 10604923
• 负责人: CATO T. LAURENCIN
• 金额: $ 16.14万
• 依托单位: UNIVERSITY OF CONNECTICUT SCH OF MED/DNT
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10604923
• 关键词: Musculoskeletal; Regenerative engineering; Tissues; Training Programs

PROJECT SUMMARY / ABSTRACT We propose a novel NIAMS doctoral T32 Program, Regenerative Engineering of Musculoskeletal Tissues: A Convergence Doctoral Training Program, which offers inter-disciplinary research areas at the University of Connecticut (UConn) combining biomedical science and engineering faculties. Regenerative Engineering is defined as the Convergence of advanced materials science, stem cell science, physics, developmental biology and clinical translation for the regeneration of complex tissues and organ systems. The T32 Program will enroll 3 Ph.D. candidates per year and support each for 2 years of Graduate School. The students will be drawn from graduate programs at UConn (School of Medicine and School of Engineering). The students will then apply for T32 support at the end of Year 1 of graduate school to be supported for Years 2-3. They will all receive their Ph.D. from the Graduate School at UConn. The T32 Program will offer trainees a broad level of expertise in research and instruction based on the research, educational, and clinical experiences of the biomedical and engineering faculty who serve as preceptors. Trainees will become experts in regenerative engineering and its foundations to work towards the alleviation of human disease and musculoskeletal injuries by means of tissue regeneration. Musculoskeletal regeneration is a field ripe for an inventive approach based on convergence to address challenging issues, advance technology and further fundamental knowledge for therapeutic applications. At the center of the Convergence approach is the understanding that new solutions in regeneration will take place through an ‘un-siloed’ approach. Thus, Regenerative Engineering welcomes ideas and research across a gamut of disciplines. The T32 Program has preceptorship commitments from 20 distinguished faculty at UConn (representing Biomedical Engineering, Cell Biology, Computer Science, Genetics and Genome Sciences, Materials Science, Mechanical Engineering, Molecular Biology and Biophysics, Oral Health, Orthopedic Surgery). This eminent group of investigators is well funded and published to provide the primary research training and serve as role models for doctoral trainees. The T32 Program goals are to educate, support and enhance the training of individuals dedicated to careers as independent clinical translational and basic scientists in regenerative engineering. Our Program strengths include its interdisciplinary and collaborative research in biomedical science and engineering, interactions with diverse trainees and faculty, training in contemporary research methodologies, and successful preceptors. T32 Program administration through the Connecticut Convergence Institute for Translation in Regenerative Engineering will provide the experience to recruit diverse trainees, including minorities, implement the curriculum, and train a new cadre of convergence scientists.

项目概要/摘要 我们提出了一个新颖的 NIAMS 博士 T32 项目：肌肉骨骼再生工程 组织：融合博士培训计划，提供跨学科研究领域 康涅狄格大学 (UConn) 结合了生物医学科学和工程学院。 再生工程被定义为先进材料科学、干细胞的融合 复杂组织再生的科学、物理学、发育生物学和临床转化 T32 计划每年将招收 3 名博士生，并为每名博士生提供 2 名资助。 研究生院的学生将从康涅狄格大学（康涅狄格大学）的研究生课程中选拔。 然后，学生将在第一年结束时申请 T32 支持。 他们都将获得研究生院的博士学位。 康涅狄格大学的 T32 项目将为学员提供广泛的研究和专业知识。 基于生物医学和医学领域的研究、教育和临床经验的指导 作为导师的工程学院的学员将成为再生工程方面的专家。 及其致力于减轻人类疾病和肌肉骨骼损伤的基金会 肌肉骨骼再生是一个适合创新方法的领域。 基于融合来解决具有挑战性的问题，推进技术和进一步的基础 融合方法的核心是理解治疗应用的知识。 新的再生解决方案将通过“非孤立”的方法来实现，因此，再生。 工程学欢迎跨学科的想法和研究。 康涅狄格大学 20 名杰出教师（代表生物医学 工程学、细胞生物学、计算机科学、遗传学和基因组科学、材料科学、 机械工程、分子生物学和生物物理学、口腔健康、骨科手术）。 杰出的研究人员小组拥有充足的资金和出版物，可以提供主要的研究培训和 成为博士生的榜样 T32 计划的目标是教育、支持和提高。 对致力于独立临床转化和基础科学家职业的个人进行培训 我们的项目优势包括跨学科和协作性。 生物医学科学与工程研究、与不同学员和教师的互动、培训 当代研究方法论和成功的导师 T32 项目管理。 通过康涅狄格州再生工程翻译融合研究所将提供 招募包括少数族裔在内的多元化学员、实施课程和培训新学员的经验 融合科学家的骨干队伍。