Regenerative Engineering of Musculoskeletal Tissues- a Convergence Doctoral Training Program

肌肉骨骼组织再生工程-融合博士培训项目

• 批准号: 10429991
• 负责人: CATO T. LAURENCIN
• 金额: $ 19.17万
• 依托单位: UNIVERSITY OF CONNECTICUT SCH OF MED/DNT
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10429991
• 关键词: Musculoskeletal; Regenerative engineering; Tissues; Training Programs

PROJECT SUMMARY / ABSTRACT We propose a novel NIAMS doctoral T32 Program, Regenerative Engineering of Musculoskeletal Tissues: A Convergence Doctoral Training Program, which offers inter-disciplinary research areas at the University of Connecticut (UConn) combining biomedical science and engineering faculties. Regenerative Engineering is defined as the Convergence of advanced materials science, stem cell science, physics, developmental biology and clinical translation for the regeneration of complex tissues and organ systems. The T32 Program will enroll 3 Ph.D. candidates per year and support each for 2 years of Graduate School. The students will be drawn from graduate programs at UConn (School of Medicine and School of Engineering). The students will then apply for T32 support at the end of Year 1 of graduate school to be supported for Years 2-3. They will all receive their Ph.D. from the Graduate School at UConn. The T32 Program will offer trainees a broad level of expertise in research and instruction based on the research, educational, and clinical experiences of the biomedical and engineering faculty who serve as preceptors. Trainees will become experts in regenerative engineering and its foundations to work towards the alleviation of human disease and musculoskeletal injuries by means of tissue regeneration. Musculoskeletal regeneration is a field ripe for an inventive approach based on convergence to address challenging issues, advance technology and further fundamental knowledge for therapeutic applications. At the center of the Convergence approach is the understanding that new solutions in regeneration will take place through an `un-siloed' approach. Thus, Regenerative Engineering welcomes ideas and research across a gamut of disciplines. The T32 Program has preceptorship commitments from 20 distinguished faculty at UConn (representing Biomedical Engineering, Cell Biology, Computer Science, Genetics and Genome Sciences, Materials Science, Mechanical Engineering, Molecular Biology and Biophysics, Oral Health, Orthopedic Surgery). This eminent group of investigators is well funded and published to provide the primary research training and serve as role models for doctoral trainees. The T32 Program goals are to educate, support and enhance the training of individuals dedicated to careers as independent clinical translational and basic scientists in regenerative engineering. Our Program strengths include its interdisciplinary and collaborative research in biomedical science and engineering, interactions with diverse trainees and faculty, training in contemporary research methodologies, and successful preceptors. T32 Program administration through the Connecticut Convergence Institute for Translation in Regenerative Engineering will provide the experience to recruit diverse trainees, including minorities, implement the curriculum, and train a new cadre of convergence scientists.

项目概要/摘要 我们提出了一个新颖的 NIAMS 博士 T32 项目：肌肉骨骼再生工程 组织：融合博士培训计划，提供跨学科研究领域 康涅狄格大学 (UConn) 结合了生物医学科学和工程学院。 再生工程被定义为先进材料科学、干细胞的融合 复杂组织再生的科学、物理学、发育生物学和临床转化 和器官系统。 T32项目将招收博士生3名。每年候选人并支持每人 2 研究生院的年数。这些学生将从康涅狄格大学（康涅狄格大学）的研究生课程中选拔。 医学院和工程学院）。学生将在年底申请 T32 支持 1 研究生院 2-3 年级获得支持。他们都将获得博士学位。来自研究生 学校在康涅狄格大学。 T32 计划将为学员提供广泛的研究和专业知识水平 基于生物医学和医学领域的研究、教育和临床经验的指导 担任导师的工程教师。学员将成为再生工程专家 及其致力于减轻人类疾病和肌肉骨骼损伤的基金会 组织再生的手段。肌肉骨骼再生是一个适合创新方法的领域 基于融合来解决具有挑战性的问题，推进技术和进一步的基础 治疗应用的知识。融合方法的核心是 了解再生的新解决方案将通过“非孤立”方法实现。因此， 再生工程欢迎跨学科的想法和研究。 T32 康涅狄格大学 20 名杰出教师（代表 生物医学工程、细胞生物学、计算机科学、遗传学和基因组科学、材料 科学、机械工程、分子生物学和生物物理学、口腔健康、骨科 外科手术）。这个杰出的研究小组资金充足，并发表了论文，以提供主要的研究成果 研究培训并成为博士生的榜样。 T32 计划的目标是 教育、支持和加强对致力于独立临床职业的个人的培训 再生工程领域的转化和基础科学家。我们的计划优势包括 生物医学科学与工程的跨学科和协作研究，与 多样化的学员和教师，接受当代研究方法的培训，并取得成功 导师。 T32 项目通过康涅狄格翻译融合研究所进行管理 再生工程博士将提供招募不同学员的经验，包括 少数民族，实施课程，并培养一支新的融合科学家骨干队伍。