Optimizing the Pulse Physiology Engine to Meet Medical Simulation Community Needs

优化脉冲生理学引擎以满足医学模拟社区的需求

基本信息

批准号：
10609281
负责人：
Rachel Clipp
金额：
$ 36.28万
依托单位：
KITWARE, INC.
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-09-01 至 2025-05-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10609281
关键词：
Address Administrative Supplement Adverse event Anatomy Architecture Area Benchmarking Cholecystectomy Code Communities Computer Models Computer software Data Development Disease Documentation Educational workshop Effectiveness Ensure Environment Equipment Malfunction Event Feedback Funding Opportunities Goals Government Grant Human Resources Industry Injury Java Language Machine Learning Medical Methods Minor Modeling Operative Surgical Procedures Outcome Assessment Patient Care Patients Performance Physiologic pulse Physiological Physiology Publications Pythons Running Software Tools Source Code Speed Surgeon Surgical Error System Technology Testing Time Training Visualization base bile duct care providers computing resources design haptics improved interest medical specialties models and simulation open data open source parent grant physiologic model resilience response simulation skill acquisition skills software development symposium technology development tool verification and validation virtual virtual reality simulator virtual surgery

项目摘要

1 Project Summary 2 The objective of our current R01 project, “Surgical Simulator for Improving Skill Proficiency and Resilience”, is 3 to design, develop, and validate methods by which simulation technologies can be used by practicing surgeons. 4 This project is extending the interactive Medical Simulation Toolkit (iMSTK) by developing software templates 5 for rare and adverse event simulation including physiological modeling, automating skill assessment, and 6 performance management in surgical simulations, which are critical for building powerful simulation applications 7 for practicing surgeons. Physiology remains an aspect of interactive real-time simulation that is rarely dealt with. 8 In most instances physiological models are developed separately without coordination with interactive surgical 9 simulation. In our current grant, we are integrating Kitware’s open source Pulse Physiology Engine with iMSTK 10 to build a closed-loop physiology model that handles local physiology changes and global, systemic physiological 11 responses. We are demonstrating these new developments by building a virtual surgical simulator for 12 cholecystectomy with bile duct injury and other rare complications that occur in this type of surgery. The goals 13 of our supplement are to 1) improve the computational efficiency of Pulse, 2) advance the external interfaces for 14 Pulse, including the Unity Asset, and 3) engage and promote Pulse to expand the user community. These goals 15 will support the parent grant by 1) improving computational efficiency to ensure that Pulse does not engage 16 critical computational resources required for graphical render, displacement and force calculations, and haptic 17 interface integration and 2) making Pulse more readily accessible via external interfaces, such as Unity, which 18 is the simulator environment for our parent grant. The supplement will also have a significant impact on medical 19 simulation in general by improving the accessibility of the Pulse via additional external interfaces, such as an 20 Unreal Plugin and interface language support, including Python, C#, and Java. We plan to engage the community 21 via publications, software releases, blog posts, and a workshop at a computational modeling conference. We 22 will engage Kitware’s well-respected software development team with the Key Personnel of the parent grant to 23 advance the Pulse platform and engage with our community of users. 24 25

1 项目概要 2 我们当前的 R01 项目“提高技能熟练程度和复原力的手术模拟器”的目标是 3 设计、开发和验证执业外科医生可以使用模拟技术的方法。 4 该项目通过开发软件模板来扩展交互式医疗模拟工具包 (iMSTK) 5 用于罕见和不良事件模拟，包括生理建模、自动化技能评估和 6 手术模拟中的性能管理，这对于构建强大的模拟应用程序至关重要 7 对于执业外科医生来说，生理学仍然是交互式实时模拟中很少涉及的一个方面。 8 在大多数生理情况下，模型是单独开发的，没有与交互式手术协调 9 模拟在我们当前的资助中，我们正在将 Kitware 的开源脉冲生理学引擎与 iMSTK 集成。 10 建立闭环生理学模型，处理局部生理学变化和全局、系统生理学 11 回应我们正在通过构建虚拟手术模拟器来展示这些新进展。 12 胆囊切除术伴有胆管损伤和此类手术中出现的其他罕见并发症。我们的13个补充是1）提高Pulse的计算效率，2）改进外部接口 14 Pulse，包括 Unity 资产，以及 3) 参与并推广 Pulse 以扩大用户社区这些目标。 15 将通过 1) 提高计算效率来支持家长拨款，以确保 Pulse 不会参与图形渲染、位移和力计算以及触觉所需的 16 个关键计算资源 17 接口集成，2) 使 Pulse 更容易通过外部接口访问，例如 Unity， 18是我们家长补助金的模拟器环境，也会对医疗产生重大影响。 19 一般通过额外的外部接口（例如 20 个虚幻插件和界面语言支持，包括 Python、C# 和 Java 我们计划让社区参与进来。 21 通过出版物、软件发布、博客文章和计算建模会议上的研讨会。 22 将让 Kitware 备受尊敬的软件开发团队与母公司的关键人员合作， 23 推进 Pulse 平台并与我们的用户社区互动。 24 二十五