Pilot Projects Program

试点项目计划

基本信息

批准号：
10263339
负责人：
Joseph J Crisco
金额：
$ 11.04万
依托单位：
RHODE ISLAND HOSPITAL
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
起止时间：
2017-09-01 至 2024-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10263339
关键词：
Area Basic Science Biomedical Engineering Biomedical Research Biotechnology Cartilage Centers of Research Excellence Clinical Collaborations Demography Development Diagnostic Economic Development Education Environment Extramural Activities Feasibility Studies Fostering Funding Grant Health Hospitals Human Institutes Joints Knowledge Learning Mentors Motion Musculoskeletal Orthopedics Outcome Measure Patient Care Patients Phase Pilot Projects Prevention strategy Preventive Principal Investigator Research Research Infrastructure Research Personnel Resources Rheumatology Rhode Island Science Scientist Side Source Strategic Planning Structure Students Therapeutic Training Translational Research Translations United States National Institutes of Health Universities Vision arthropathies base career human disease improved innovation interdisciplinary approach interdisciplinary collaboration programs recruit repaired skeletal success tool translational approach undergraduate student

Area Basic Science Biomedical Engineering Biomedical Research Biotechnology Cartilage Centers of Research Excellence Clinical Collaborations Demography Development Diagnostic Economic Development Education Environment Extramural Activities Feasibility Studies Fostering Funding Grant Health Hospitals Human Institutes Joints Knowledge Learning Mentors Motion Musculoskeletal Orthopedics Outcome Measure Patient Care Patients Phase Pilot Projects Prevention strategy Preventive Principal Investigator Research Research Infrastructure Research Personnel Resources Rheumatology Rhode Island Science Scientist Side Source Strategic Planning Structure Students Therapeutic Training Translational Research Translations United States National Institutes of Health Universities Vision arthropathies base career human disease improved innovation interdisciplinary approach interdisciplinary collaboration programs recruit repaired skeletal success tool translational approach undergraduate student

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项目摘要

Pilot Projects Program R&R Other Project Info 7. Project Summary/Abstract The specific aims for the Pilot Projects Program are 1) to provide support for proof-of-concept and feasibility studies in the translation of discoveries for improving and repairing skeletal, cartilage and joint health, 2) to mentor early stage basic science investigators in the field of skeletal health and repair for their development and attainment of independent status using their ability to obtain significant extramural funding (NIH RO1 or equivalent) as an outcome measure, and 3) to mentor early stage clinician-scientists in orthopaedics and rheumatology and related fields for developing an academic career through collaborations with basic science investigators using their ability to obtain extramural funding as a Co-Investigator and Principal Investigator as an outcome measure. The significance of the proposed pilot projects program is its alignment with this University-based strategic plan providing focus and an aggregation of resources that will accelerate discoveries and translations. We will accomplish these aims with an innovative approach of fostering collaborative teams of scientists and clinicians with the specific focus on translational strategies for discoveries aimed at improving and repairing skeletal, cartilage and joint health. In addition to supporting and promoting feasibility studies in the translation of discoveries for improving and repairing skeletal, cartilage and joint health, we will provide mentoring for the both the basic scientists and clinician-scientists. This will be accomplished with direct mentoring and with a didactic program. The pilot program itself will be supported by a mentoring council that will assist project mentors and coordinate mentoring efforts across the program. Given the high success of the Pilot Projects supported under our Phase I & II, we are extremely enthusiastic the Phase III pilot projects endpoint on the continuum is the translation of discoveries into real world, marketable therapies or diagnostic tools that help patients.

试点项目计划 R＆R其他项目信息 7。项目摘要/摘要试点项目计划的具体目标是1）为概念证明和可行性提供支持在改善和修复骨骼，软骨和关节健康的发现翻译中的研究，2）导师早期阶段的基础科学研究者在骨骼健康领域的发展和维修领域的发展并使用其获得大量壁外资金的能力（NIH RO1或等效）作为结果指标，3）指导早期阶段临床医生在骨科和风湿病学和相关领域通过与基础科学合作发展学术生涯调查人员利用他们作为共同投资者和首席研究员获得壁外资金的能力结果度量。拟议的试点项目计划的重要性在于它的一致性基于大学的战略计划提供重点和资源的汇总，这些资源将加速发现和翻译。我们将通过促进的创新方法来实现这些目标科学家和临床医生的合作团队，特别关注发现的转化策略旨在改善和修复骨骼，软骨和关节健康。除了支持和促进在改善和修复骨骼，软骨和关节健康的发现翻译中的可行性研究，我们将为基础科学家和临床医生科学家提供指导。这将完成通过直接指导和教学计划。试点计划本身将由指导支持理事会将协助项目导师并协调整个计划的指导工作。给定高在我们的第一阶段和II期间支持的飞行员项目的成功，我们非常热情连续性的项目端点是将发现转化为现实世界，可销售疗法或诊断工具可以帮助患者。