Core G: Research Education Component (RL5)

核心 G：研究教育部分 (RL5)

基本信息

批准号：
10264502
负责人：
PATRICIA A BOYLE
金额：
$ 5.99万
依托单位：
RUSH UNIVERSITY MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-09-01 至 2026-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10264502
关键词：
Address Aging Alzheimer disease prevention Alzheimer&apos s Disease Area Biochemical Biological Biology Clinical Collaborations Complement Complex Data Dementia Development Diagnosis Discipline Educational Activities Epidemiology Etiology Faculty Future Goals Home Institution Interdisciplinary Study Internships Knowledge Language Learning Link Mentors Mentorship Methodology Molecular Neuroepidemiology Neurology Neuropsychology Neurosciences Pathogenesis Research Research Personnel Research Priority Resources Scientist Structure Talents Techniques Training Work base design education research ethnic diversity experience health disparity innovation interdisciplinary collaboration knowledge base multi-ethnic multidisciplinary neuroimaging neuropathology novel novel strategies personalized approach preference racial diversity symposium

Address Aging Alzheimer disease prevention Alzheimer&apos s Disease Area Biochemical Biological Biology Clinical Collaborations Complement Complex Data Dementia Development Diagnosis Discipline Educational Activities Epidemiology Etiology Faculty Future Goals Home Institution Interdisciplinary Study Internships Knowledge Language Learning Link Mentors Mentorship Methodology Molecular Neuroepidemiology Neurology Neuropsychology Neurosciences Pathogenesis Research Research Personnel Research Priority Resources Scientist Structure Talents Techniques Training Work base design education research ethnic diversity experience health disparity innovation interdisciplinary collaboration knowledge base multi-ethnic multidisciplinary neuroimaging neuropathology novel novel strategies personalized approach preference racial diversity symposium

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项目摘要

ABSTRACT – RESEARCH EDUCATION COMPONENT The overall goal of the Research Education Component (REC) is to develop high quality investigators engaged in transformative interdisciplinary research on the etiology, pathogenesis, diagnosis, treatment, and prevention of Alzheimer’s dementia and related dementias (AD/ADRD). Recent advances, particularly the application of high throughput biochemical and molecular techniques and novel approaches to integrate multilevel and multiethnic data, offer an unprecedented opportunity for scientific progress but also pose unique challenges for investigators engaged in aging research. Optimization of emerging methodologies in high impact research requires talented scientists capable of sharing knowledge and methodologies across disciplines. Truly interdisciplinary research can be difficult to accomplish, however. Barriers include limited shared knowledge among investigators from diverse disciplines and changing dynamics in the field; junior investigators increasingly hold expertise in emerging methodologies but may lack a full appreciation of their potential to address critical gaps in knowledge, and senior investigators with a deep understanding of these gaps may be unfamiliar with emerging methodologies. New integrative and multidirectional learning opportunities (i.e., learning flows from investigators of all levels across disciplines and institutions) are needed to facilitate efficient knowledge transfer and productive partnership among diverse investigators. The REC will capitalize on a highly multidisciplinary faculty and implement an integrative and multidirectional approach to facilitate truly interdisciplinary aging research with a focus on emerging methodologies and high priority areas such as health disparities. Toward this end, the REC will provide cross-disciplinary training in key disciplines relevant to aging and link this to new training in emerging methodologies and health disparities research using the highly unique clinical, biologic and biospecimen data generated at Rush. The REC will work with all other Rush ADRC Cores to implement and oversee a variety of educational activities, including 1) a monthly Neuroepidemiology of Aging Seminar; 2) intensive mini-internship training in emerging methodologies and health disparities, 3) individualized mentoring, and 4) participation in the RADC annual Aging Research Forum. Via careful integration with the other Rush ADRC Cores, the REC will develop highly skilled interdisciplinary investigators capable of leveraging contemporary approaches in high impact and innovative AD/ADRD research.

摘要 - 研究教育部分研究教育部分（REC）的总体目标是培养参与的高质量研究人员关于病因，发病机理，诊断，治疗和预防的变革性跨学科研究阿尔茨海默氏症的痴呆症和相关痴呆症（AD/ADRD）。最近的进步，特别是应用高通量生化和分子技术以及整合多级和的新方法多民族数据，为科学进步提供了前所未有的机会，但也对研究人员从事衰老研究。高影响研究中新兴方法的优化需要有才华的科学家，能够跨学科共享知识和方法。真的但是，跨学科研究可能很难完成。障碍包括有限的共同知识在潜水员学科的研究人员中，该领域的动态变化；初级调查员越来越多地拥有新兴方法的专业知识，但可能缺乏对其潜力的全面认识解决知识的关键差距，高级调查人员对这些差距有深刻的了解可能是不熟悉新兴方法。新的综合和多向学习机会（即需要从学科和机构跨各个层面的研究人员学习流动），以促进高效潜水员调查员之间的知识转移和产品伙伴关系。 Rec将大写高度多学科的教职跨学科的衰老研究，重点是新兴方法和高优先级领域，例如健康差异。为此，REC将在与衰老有关的关键学科中提供跨学科培训并将其链接到新兴方法和健康差异研究中的新培训 Rush产生的临床，生物学和生物测量数据。 REC将与所有其他Rush ADRC核心一起工作实施和监督各种教育活动，包括1）衰老研讨会； 2）在新兴方法和健康差异方面进行密集的小型工程培训，3）个性化的心理，4）参加RADC年度老化研究论坛。小心与其他Rush ADRC核心的集成，REC将开发高技能的跨学科研究人员能够利用当代方法进行高影响力和创新的AD/ADRD研究。