Statistics and Data Coordinating Center

统计和数据协调中心

• 批准号: 8266897
• 负责人: LLOYD A MANCL
• 金额: $ 21.62万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8266897
• 关键词: Address; Adherence; Adverse event; Alaska; Anesthesia procedures; Area; Biometry; Childhood; Clinical; Clinical Research; Clinical Trials; Clinical Trials Data Monitoring Committees; Collaborations; Communication; Conduct Clinical Trials; Data; Data Analyses; Data Coordinating Center; Dental Research; Development; Enrollment; Ensure; Epidemiology; Funding; Goals; Hawaii; Housing; Human Resources; Information Technology; Institutional Review Boards; Internet; Intervention Studies; Lead; Leadership; Location; Manuals; Manuscripts; Masks; Monitor; National Institute of Dental and Craniofacial Research; Online Systems; Oral health; Patients; Performance; Preparation; Procedures; Process; Protocols documentation; Randomized; Registries; Reporting; Research; Research Contracts; Research Infrastructure; Research Methodology; Research Personnel; Research Project Grants; Role; Sample Size; Scheme; School Dentistry; Site; Support System; System; Technology; Training; Training Programs; Universities; Washington; Web communication; Work; abstracting; base; data management; design; experience; follow-up; health application; health disparity; member; operation; practice-based research network; programs; quality assurance; research study; response; statistics; success

Statistics and Data Coordinating Center (S&DCC) Abstract The overall goal of the proposed research project is to establish the Statistics and Data Coordinating Center (S&DCC) for the Northwest/Alaska/Hawaii Center to Reduce Oral Health Disparities. Both the S&DCC and the Research Program Administrative Center (RPAC) will be based at the University of Washington School of Dentistry. The S&DCC will build on the strengths of an existing Biostatistics group that has a successful long-term track record in biostatistical methodologic research and collaboration in clinical dental research, as well as the expertise and extensive experience of Axio Research, a Contract Research Organization nearby in Seattle. In response to RFA-DE-08-008 issued by the NIDCR, the S&DCC will provide the scientific leadership in design and implementation of interventional research and the infrastructure needed for the conduct of multiple intervention studies and developmental research studies to address important oral health disparities. Five specific aims will be achieved: 1) Establish the infrastructure and develop Standard Operating Procedures for the S&DCC; 2) Create a reliable and customizable Web portal for communications throughout the Center; 3) Participate with the RPAC in training programs; 4) Assist the RPAC and Center investigators in the design and initiation of two core intervention studies and three developmental research projects, and ensure that IRB approvals are obtained before any patients are enrolled; and 5) Provide all biostatistical support for the implementation of all approved research studies, including the coordination of the Data and Safety Monitoring Boards. These specific aims will be achieved by a team of investigators with complementary sets of expertise and experience. The Director of the S&DCC will be Dr. Lloyd Mancl, who is currently the lead Biostatistician of the Data Coordinating Center of NW PRECEDENT PBRN and an active member of the Biometry Core for the Northwest/Alaska Center to Reduce Oral Health Disparities. The Data Management and Information Technology Support Unit of the S&DCC will be led by Ms. Alice Birnbaum, who is currently Deputy Director of the Data Management Unit of the data coordinating center of NW PRECENDENT and Director of data management for the Pediatric Anesthesia Quality Improvement registry. Together, these investigators have the necessary expertise and experience in all areas that are critical for the success of the Statistics and Data Coordinating Center for support of oral health research in the Northwest/Alaska/Hawaii Center to Reduce Oral Health Disparities.

统计和数据协调中心（S&DCC） 抽象的 拟议研究项目的总体目标是建立统计和数据协调中心 (S&DCC) 西北/阿拉斯加/夏威夷中心减少口腔健康差异。 S&DCC 和 研究计划管理中心 (RPAC) 将设在华盛顿大学医学院 牙科。 S&DCC 将建立在现有生物统计小组的优势之上，该小组拥有长期成功的经验 在生物统计方法学研究和临床牙科研究合作方面的跟踪记录，以及 Axio Research（西雅图附近的合同研究组织）的专业知识和丰富经验。 为了响应 NIDCR 发布的 RFA-DE-08-008，S&DCC 将在以下方面提供科学领导： 设计和实施介入研究以及进行多项研究所需的基础设施 干预研究和发展研究，以解决重要的口腔健康差异。五 将实现的具体目标： 1) 建立基础设施并制定标准操作程序 S&DCC； 2) 创建一个可靠且可定制的门户网站，用于整个中心的通信； 3） 参与 RPAC 培训计划； 4) 协助RPAC和中心研究者设计和 启动两项核心干预研究和三个发展研究项目，并确保IRB 在招募任何患者之前获得批准； 5) 提供所有生物统计支持 实施所有批准的研究，包括数据和安全监测的协调 董事会。这些具体目标将由具有​​互补专业知识的研究团队来实现 和经验。 S&DCC 的主任将是 Lloyd Mancl 博士，他目前是 NW PRECEDENT PBRN 的数据协调中心，也是生物测定核心的活跃成员 西北/阿拉斯加减少口腔健康差异中心。数据管理和信息 S&DCC 技术支持部门将由 Alice Birnbaum 女士领导，她现任 S&DCC 副主任 NW PRECENDENT 数据协调中心数据管理组兼数据总监 儿科麻醉质量改进登记处的管理。这些研究人员共同拥有 对统计和数据的成功至关重要的所有领域的必要专业知识和经验 支持西北/阿拉斯加/夏威夷口腔健康研究协调中心减少口腔疾病中心 健康差异。