Life After Sport: Prior Injury and Sedentary Behavior as Mechanisms of Later Poor Health

运动后的生活：先前的受伤和久坐行为是后来健康状况不佳的机制

基本信息

批准号：
10253367
负责人：
Jacob J Capin
金额：
$ 39.76万
依托单位：
MARQUETTE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-09-22 至 2026-08-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10253367
关键词：
Adult Age American Athletic Behavior Therapy Body Composition Body fat Chronic Disease Clinical Counseling Data Degenerative polyarthritis Delaware Development Disease Doctor of Philosophy Equipment Exercise Faculty Female Funding Future General Population Goals Guidelines HRK gene Health Health Promotion Injury Intervention Intervention Studies Knee Injuries Laboratories Lead Life Longevity Longitudinal Studies Manuscripts Medical Mentors Methods Minority Musculoskeletal National Institute of Child Health and Human Development Outcome Participant Pattern Peer Review Physical activity Physical therapy Play Population Populations at Risk Positioning Attribute Procedures Publications Quality of life Recording of previous events Rehabilitation therapy Research Research Assistant Research Support Research Training Resources Risk Risk Factors Scientist Services Sports Testing Time Underrepresented Populations United States United States National Institutes of Health Universities Walking Work aging population cardiometabolism cardiovascular disorder risk career career development chronic pain cohort college cost design disability doctoral student early onset experience hamstring health related quality of life healthspan high school improved innovation longitudinal analysis male middle age moderate-to-vigorous physical activity mortality musculoskeletal injury novel peer physical therapist prevent professor programs quadriceps muscle sedentary sedentary lifestyle success

项目摘要

PROJECT SUMMARY/ABSTRACT Approximately 8.5 million high school and collegiate athletes engage annually in competitive sport. While competitive sport offers many benefits, it also poses underappreciated risks to long-term health. Competitive sport profoundly increases risk for injury (e.g., knee injury) and may position athletes for early onset of chronic diseases (e.g., osteoarthritis), chronic pain, poor health-related quality of life, and disability. Preliminary evidence indicates former athletes in mid-life (mean age 53) perform worse on functional tests than non-athlete peers, but did not account for prior injury status. Quantifying function in former athletes with and without a prior injury and non-athlete controls is therefore critical to informing targeted interventions and ultimately increasing healthspans and quality of life. One modifiable factor that may explain the association between sports participation and poor long-term health is physical activity (PA) patterns including prolonged sedentary behavior (SB). Even among adults who meet recommended PA guidelines, SB is strongly associated with a host of poor outcomes including chronic disease and all-cause mortality. Current male professional athletes are substantially more sedentary outside their practice times than non-athletes, but whether this harmful pattern of SB also exists in amateur (e.g., high school, collegiate) or female athletes or persists in former athletes is unknown. The long-term research goal is to improve musculoskeletal, cardiometabolic, and general health and function across the lifespan of male and female former athletes, emphasizing early behavioral interventions that prevent this underrepresented and at-risk population from developing chronic diseases by mid-life. The overarching hypothesis is that former athletes, especially those with a prior injury, will have poorer function and health in mid-life and that current and former athletes will engage in greater overall and longer bouts of SB compared to matched non-athletes. Using a cross-sectional design, Aim 1 will compare function, strength, and cardiometabolic indicators among former athletes with and without prior knee injury and non- athlete matched controls in mid-life (age 45-64). Hypothesis 1 is that former athletes with a prior injury will have the poorest (1a) function (30-second chair stand, 6-minute walk, stair climb), (1b) quadriceps and hamstring strength, and (1c) cardiometabolic indicators (body composition, cardiovascular disease risk). Aim 2 will compare SB and PA patterns in current (age 18-25) and mid-life former athletes to matched non-athlete controls. Hypothesis 2.1 is that current athletes will have greater SB, longer SB bouts, and higher levels of moderate-to-vigorous PA. Hypothesis 2.2 is that former athletes in mid-life will have greater SB, longer SB bouts, and lower PA levels. Identifying and ultimately intervening on risk factors for early chronic disease will not only benefit many millions of male and female former athletes—a group in which minorities are increasingly more represented than in the overall United States population—but also provide an efficient means to prevent or delay chronic disease development in the population at large, a recent NIH emphasis (e.g., PA-18-849).

项目摘要/摘要每年约有850万高中和大学运动员从事竞争运动。尽管竞争性运动提供了许多好处，它还给长期健康带来了不足的风险。竞争的运动深刻增加了受伤的风险（例如，膝盖受伤），可能会使运动员提早发作疾病（例如骨关节炎），慢性疼痛，与健康相关的生活质量差和残疾。初步的证据表明，在功能测试中，中年运动员的前期运动员（平均年龄53岁）的表现要比非运动员差同龄人，但没有考虑事先的伤害状况。有或没有先验的前运动员中的量化功能因此，伤害和非运动员控制对于告知目标干预措施并最终增加至关重要健康范围和生活质量。一个可修改的因素，可以解释运动之间的关联参与和长期健康不良是体育锻炼（PA）模式，包括长时间久坐的行为（SB）。即使在符合建议PA指南的成年人中，SB也与许多不良结果，包括慢性疾病和全因死亡率。目前的男性职业运动员与非运动员相比，在练习时间之外的久坐时间要大得多，但是这种有害 SB的模式也存在于业余（例如，高中，大学）或女运动员或形式的持续运动员是未知的。长期研究目标是改善肌肉骨骼，心脏代谢和一般在男性和女性前运动员的整个寿命中的健康和功能，强调早期行为防止这种人数不足和处于危险人群的干预措施受到慢性疾病的发展中年。总体假设是，前运动员，尤其是那些先前受伤的运动员，会较差中年的功能和健康，当前和前运动员将参与更大和更长的时间与匹配的非运动员相比，SB的回合。使用横截面设计，AIM 1将比较功能，有或没有事先膝盖损伤和非膝关节的前运动员的力量和心脏代谢指标运动员在中年（45-64岁）中匹配对照。假设1是，以前受伤的前运动员将有最贫穷（1A）功能（30秒椅子架，步行6分钟，堆叠器攀爬），（1B）股四头肌和腿筋强度和（1C）心脏代谢指标（身体成分，心血管疾病风险）。 AIM 2意志比较当前（18-25岁）和中年前运动员的SB和PA模式与非运动员相匹配控件。假设2.1是当前的运动员将具有更大的SB，更长的SB回合和更高的水平中度到vig的PA。假设2.2是中年的前运动员将具有更大的SB，更长的SB 回合，PA级别降低。确定并最终干预早期慢性病的危险因素不仅使数百万的男性和女性前运动员受益 - 少数群体越来越多比美国整体人口更有代表性，但也提供了一种有效的手段或者延迟慢性疾病的总体疾病发展，最近的NIH重点（例如PA-18-849）。