Administrative Core

行政核心

• 批准号: 10589642
• 负责人: Leonidas Stamatatos
• 金额: $ 16.34万
• 依托单位: FRED HUTCHINSON CANCER CENTER
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-01-30 至 2027-12-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10589642
• 关键词: Accounting; Achievement; Agreement; Antigens; B-Cell Activation; B-Cell Antigen Receptor; Budgets; Clinical; Clinical Investigator; Collaborations; Communication; Data; Dedications; Development Plans; Ensure; Expenditure; Funding; Goals; Grant; HIV-1; IACUC; Individual; Infrastructure; Institution; Leadership; Legal; Messenger RNA; Monitor; National Institute of Allergy and Infectious Disease; Participant; Policies; Policy Compliance; Preparation; Principal Investigator; Protocols documentation; Publications; RNA vaccine; Regulation; Regulatory Affairs; Reporting; Research; Research Activity; Research Project Grants; Resolution; Scientific Evaluation; Self-Examination; Site; Structure; United States National Institutes of Health; clinical development; cohesion; design; inter-institutional; material transfer agreement; meetings; product development; programs; repository; research clinical testing; success; tool

ABSTRACT ADMINISTRATION CORE The Administrative Core will support the scientific and programmatic activities of our IPCAVD Program and provide the necessary infrastructure for the Program to achieve its overall research objectives and milestones in the most efficient and effective manner. This Core has the following specific aims: (1) to provide scientific leadership and coordination of the IPCAVD’s activities, assuring achievement of our scientific goals while maximizing scientific collaboration; (2) to optimize communication among the participating Scientific and Clinical investigators; between Project Leaders, the external Scientific Advisory Board, the NIAID and our Clinical Partners; and (3) to provide fiscal oversight, administrative support, and ensure regulatory and grant policy compliance. It will be led by the Principal Investigator, Dr. Leonidas Stamatatos, who will manage, oversee and coordinate the efforts of each participant in the Program, with the assistance of the Project Manager, Dr. Mingchao Shen. A group of external Scientific Advisors will be formed to oversee the scientific activities of the IPCAVD and provide advice and support. This Core will oversee and integrate the execution of the Research Plans, Product Development Plan, and Clinical Development Plan. This Core oversees all aspects of this Program including scientific issues, regulatory affairs, finance, communication, coordination and administration of each of the Cores and Projects. This Core will ensure that expenditures and projections are commensurate with the goals of the overall project; monitor the fiscal and functional aspects of all subcontracts; and coordinate with the Offices of Sponsored Research at participating Institutions for the disbursement, expenditure and accounting of grant funds. This Core will coordinate the preparation and submission of scientific and financial reports, facilitate the establishment of regulatory protocols and ensure regulatory compliance. Communications will be facilitated utilizing a variety of tools, including a dedicated, external IPCAVD SharePoint site, which will serve as a centralized repository for Program data, regulatory compliance documents, inter-institutional and material transfer agreements and relevant publications, abstracts and presentations.

摘要管理核心 行政核心将支持我们IPCAVD的科学和程序化活动 计划并为该计划提供必要的基础架构，以实现其整体 以最有效的方式进行研究目标和里程碑。这个核心有 以下具体目的：（1）提供IPCAVD的科学领导和协调 活动，确保实现我们的科学目标，同时最大程度地提高科学合作； （2）优化参与的科学和临床研究人员之间的交流； 在项目领导者，外部科学顾问委员会，NIAID和我们的临床上 合作伙伴； （3）提供财政监督，行政支持，并确保监管和 授予政策合规性。它将由首席调查员Leonidas Stamatatos博士领导， 谁将管理，监督和协调每个参与该计划的努力， 项目经理Mingchao Shen博士的协助。一群外部​​科学顾问 将成立以监督IPCAVD的科学活动并提供建议和支持。 该核心将监督和整合研究计划的执行，产品开发 计划和临床发展计划。该核心监督该程序的所有方面，包括 科学问题，监管事务，财务，沟通，协调和管理 每个核心和项目。该核心将确保支出和项目是 与整个项目的目标相称；监控财政和功能方面 所有分包合同；并与参与的赞助研究的办公室协调 支付，支出和贷款基金的支出，支出和会计机构。这个核心将 协调科学和财务报告的准备和提交，促进 建立监管方案并确保法规遵守。通信将 使用多种工具做好准备，包括专用的外部Ipcavd SharePoint网站， 它将作为计划数据，监管合规文件的集中式存储库， 机构间和物质转移协议以及相关出版物，摘要和 演讲。