Administrative Core

行政核心

• 批准号: 10540725
• 负责人: Leonidas Stamatatos
• 金额: $ 6.42万
• 依托单位: FRED HUTCHINSON CANCER CENTER
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-12-06 至 2024-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10540725
• 关键词: Accounting; Achievement; Affinity; Agreement; Anti-Idiotypic Antibodies; Antibodies; Antigens; B-Cell Antigen Receptor; B-Lymphocytes; Budgets; Collaborations; Communication; Data; Dedications; Development; Ensure; Evolution; Expenditure; Frequencies; Funding; Generations; Goals; Grant; HIV-1; Human; IACUC; Immune system; Immunization; Individual; Infrastructure; Institution; Knock-in Mouse; Leadership; Legal; Monitor; Mus; Participant; Policies; Policy Compliance; Preparation; Principal Investigator; Progress Reports; Protocols documentation; Publications; Quality Control; Reagent; Regulation; Regulatory Affairs; Reporting; Research; Research Activity; Research Personnel; Research Project Grants; Resolution; Resources; Scheme; Scientific Evaluation; Site; Structure; Structure of germinal center of lymph node; Testing; United States National Institutes of Health; cohesion; design; experimental study; in vivo; inter-institutional; material transfer agreement; meetings; neutralizing antibody; programs; receptor; recruit; repository; success; tool; Accounting; Achievement; Affinity; Agreement; Anti-Idiotypic Antibodies; Antibodies; Antigens; B-Cell Antigen Receptor; B-Lymphocytes; Budgets; Collaborations; Communication; Data; Dedications; Development; Ensure; Evolution; Expenditure; Frequencies; Funding; Generations; Goals; Grant; HIV-1; Human; IACUC; Immune system; Immunization; Individual; Infrastructure; Institution; Knock-in Mouse; Leadership; Legal; Monitor; Mus; Participant; Policies; Policy Compliance; Preparation; Principal Investigator; Progress Reports; Protocols documentation; Publications; Quality Control; Reagent; Regulation; Regulatory Affairs; Reporting; Research; Research Activity; Research Personnel; Research Project Grants; Resolution; Resources; Scheme; Scientific Evaluation; Site; Structure; Structure of germinal center of lymph node; Testing; United States National Institutes of Health; cohesion; design; experimental study; in vivo; inter-institutional; material transfer agreement; meetings; neutralizing antibody; programs; receptor; recruit; repository; success; tool

PROJECT SUMMARY / ABSTRACT The Administrative Core (Core A) will support the scientific and programmatic activities of our HIVRAD Program and provide the necessary infrastructure for the Program to achieve its overall research objectives and milestones in the most efficient and effective manner. Core A has the following specific aims: (1) to provide scientific leadership and coordination of the HIVRAD’s activities, assuring achievement of our scientific goals while maximizing scientific collaboration; (2) to optimize communication among the participating scientific investigators; and between Project Leaders, the Scientific Advisory Board, and the NIH Program Officer; and (3) to provide fiscal oversight, administrative support, and ensure regulatory and grant policy compliance. Core A will be led by the Principal Investigator, Dr. Leonidas Stamatatos, who will manage, oversee and coordinate the efforts of each participant in the Program, with the assistance of the Project Manager. A group of external Scientific Advisors will be formed to oversee the scientific activities of the HIVRAD and provide advice and support. This Core will oversee and integrate the execution of the research Projects and Scientific Core. Core A oversees all aspects of this Program including scientific issues, regulatory affairs, finance, communication, coordination and administration of each of the Cores and Projects. This Core will ensure that expenditures and projections are commensurate with the goals of the overall project; monitor the fiscal and functional aspects of all subcontracts; and coordinate with the Offices of Sponsored Research at participating Institutions for the disbursement, expenditure and accounting of grant funds. This Core will coordinate the preparation and submission of scientific and financial reports, facilitate the establishment of regulatory protocols and ensure regulatory compliance. Communications will be facilitated utilizing a variety of tools, including a dedicated, external SharePoint site, which will serve as a centralized repository for Program data, regulatory compliance documents, inter-institutional and material transfer agreements and relevant publications, abstracts and presentations.

项目摘要 /摘要 行政核心（核心A）将支持Hivrad的科学和程序化活动 计划并为该计划提供必要的基础架构，以实现其整体研究目标 和里程碑以最有效的方式。核心A具有以下特定目标：（1）提供 科学领导力和Hivrad活动的协调，确保实现我们的科学目标 同时最大程度地提高科学合作； （2）优化参与科学的沟通 调查人员；在项目负责人，科学顾问委员会和NIH计划官员之间；和 （3）提供财政监督，行政支持，并确保监管和授予政策合规性。 A将由首席调查员Leonidas Stamatatos博士领导，他将管理，监督和协调 在项目经理的协助下，每个参与计划的努力。一组外部 将成立科学顾问来监督希夫拉德的科学活动，并提供建议和 支持。该核心将监督和整合研究项目和科学核心的执行。 a跨该计划的各个方面，包括科学问题，监管事务，财务，沟通， 每个核心和项目的协调和管理。该核心将确保支出和 项目与整个项目的目标相称；监控财政和功能方面 所有分包合同；并与参与机构的赞助研究办公室协调 拨款资金的支出，支出和会计。该核心将协调准备工作，并且 提交科学和财务报告，促进建立监管方案并确保 法规合规性。通过各种工具，包括专用的， 外部SharePoint网站将作为计划数据的集中存储库，监管合规性 文件，机构间和物质转移协议以及相关出版物，摘要和 演讲。