DCISR for Adaptive Intervention Models in Children's Mental Health

DCISR 儿童心理健康适应性干预模型

• 批准号: 7880970
• 负责人: GERALD J AUGUST
• 金额: $ 88.76万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-24 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7880970
• 关键词: DCISR; Adaptive; Intervention; Models; Children

DESCRIPTION (provided by applicant): This Developing Center for Intervention and/or Services Research (DCISR) will develop capacity to support an innovative collaborative partnership comprised of developmental science and prevention science investigators at the University of Minnesota and community leaders representing a network of systems of care serving children's mental health in underserved urban populations. This community-academic partnership will advance a program of translational research to inform the design of adaptive models of evidence-based preventive interventions for children and youth at-risk for conduct disorder and associated psychiatric comorbidities. The mission of the DC is to improve implementation of evidence-based programs to diverse consumer populations through the development of personalized decision-making technology that uses empirical data on the needs and preferences of clients to tailor interventions. The scientific aims of the DC are to: (1) identify tailoring variables and corresponding measurement tools that will be used to adapt an evidence-based program to make it more acceptable and effective in real-world practice; (2) conduct pragmatic intervention trials to inform the construction of decision rules and decision aids for design of adaptive intervention models; and (3) conduct confirmatory randomized controlled trials to evaluate the effectiveness of adaptive intervention models relative to standard models of the evidence-based programs. Infrastructure and capacity-building aims are to: (1) fully develop four DC cores that support an integrative program of adaptive intervention science; (2) infuse of culture of scientific inquiry into the settings of community stakeholders that fosters consensus about where interventions are designed, deployed, and evaluated; and (3) develop an education and training program that fosters opportunities for the next generation of prevention and community mental health scientists. Two developmental projects are proposed to generate pilot data that will inform the design of future more definitive investigations. Developmental Study #1 will employ a pragmatic intervention trial using a SMART design to derive decision rules that will inform adaptation of an early-age targeted conduct disorders prevention program for high-risk children attending urban elementary schools. Developmental Study #2 will employ a randomized preference trial to elucidate factors that influence family decisions to select one of five intervention options for an adolescent-targeted conduct disorder prevention program. The research conducted by this DC will determine how provider and consumer choices impact effective consumer engagement and outcomes in prevention programs. The accumulated body of work will guide program users in tailoring evidence-based programs for their specific needs, populations, and settings.

描述（由申请人提供）：该干预和/或服务研究发展中心 (DCISR) 将发展能力，以支持由明尼苏达大学的发展科学和预防科学研究人员以及代表系统网络的社区领导者组成的创新合作伙伴关系为服务水平低下的城市人口中的儿童心理健康提供护理服务。这种社区-学术伙伴关系将推进一项转化研究计划，为有行为障碍和相关精神合并症风险的儿童和青少年设计基于证据的预防干预措施的适应性模型提供信息。 DC 的使命是通过开发个性化决策技术，利用有关客户需求和偏好的经验数据来定制干预措施，从而改善针对不同消费者群体的循证计划的实施。 DC 的科学目标是： (1) 确定定制变量和相应的测量工具，用于调整循证计划，使其在现实世界实践中更容易被接受和更有效； （2）进行务实的干预试验，为构建决策规则和决策辅助工具以设计适应性干预模型提供信息； (3) 进行验证性随机对照试验，以评估适应性干预模型相对于循证计划标准模型的有效性。基础设施和能力建设的目标是：(1) 充分开发四个 DC 核心，支持适应性干预科学的综合计划； (2) 将科学探究文化融入社区利益相关者的环境中，从而就干预措施的设计、部署和评估达成共识； (3) 制定教育和培训计划，为下一代预防和社区心理健康科学家创造机会。提出了两个开发项目来生成试点数据，为未来更明确的调查设计提供信息。发展研究#1将采用实用的干预试验，采用SMART设计来得出决策规则，为城市小学高危儿童调整早期有针对性的行为障碍预防计划提供信息。发展研究#2将采用随机偏好试验来阐明影响家庭决策的因素，以选择针对青少年的行为障碍预防计划的五种干预选项之一。该 DC 进行的研究将确定提供者和消费者的选择如何影响消费者的有效参与和预防计划的结果。积累的工作将指导项目用户根据其特定需求、人群和环境定制基于证据的项目。