Advancing Standardization of Neurophysiology Data Through Dissemination of NWB

通过 NWB 的传播推进神经生理学数据的标准化

• 批准号: 10573260
• 负责人: Benjamin K Dichter
• 金额: $ 117.35万
• 依托单位: UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-04-01 至 2026-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10573260
• 关键词: Address; Adopted; Area; Award; BRAIN initiative; Behavior; Brain; Catalogs; Communities; Computer software; Conscious; Data; Data Analyses; Data Set; Documentation; Ecosystem; Emerging Technologies; Esthesia; Event; Goals; Imaging technology; Incentives; Institution; Investments; Laboratories; Learning; Measures; Memory; Metadata; Methods; Neurons; Neurosciences; Neurosciences Research; Perception; Persons; Process; Protocols documentation; Publications; Reproduction; Research; Research Personnel; Resources; Science; Scientist; Services; Standardization; Structure; Technology; Testing; Thinking; Time; Training; United States National Institutes of Health; Work; cost; data acquisition; data integration; data management; data pipeline; data reuse; data sharing; data standards; data tools; design; experimental study; improved; neurophysiology; new technology; support tools; tool; training opportunity; working group

PROJECT SUMMARY Lack of standards for neurophysiology data and related metadata is the single greatest impediment to fully extracting return on investment from neurophysiology experiments. One of the greatest questions in science today is understanding how the brain works and gives rise to thoughts, memories, perception, and consciousness. To address this challenge, neurophysiologists within the NIH BRAIN initiative and around the world perform experiments that measure neuronal activity from different parts of the brain and relate that activity to sensation and behavior. A key component of the BRAIN Initiative is to support sharing of these rich datasets and extend their value by enabling reuse of data within and across labs. The goal of this proposal is to disseminate Neurodata Without Borders (NWB) neurophysiology technologies developed as part of the NIH BRAIN Initiative broadly to the neuroscience research community. NWB is an award-winning, community-driven data standard and software ecosystem for neurophysiology. To facilitate data sharing and reuse, the NWB format standardizes how neurophysiology data and associated metadata are stored, and the NWB software enables researchers to access and save data in the NWB format easily and efficiently. Several leading neuroscience labs and institutions now produce data in NWB; however, a substantial energy barrier remains for labs to standardize their data. To lower the barrier of adopting NWB, we propose a multifaceted plan to make NWB easier to use by focusing on the needs of 1) neuroscience researchers and laboratories by enhancing user training, support, and coverage of new technologies and 2) neuroscience tools and technologies by maintaining core NWB technologies and integrating with a wide array of powerful data tools and technologies. With NWB data as a target, scientists can access, manage, and share data using common protocols, while developers have a common format on top of which to build tools. By targeting these two areas simultaneously, we aim to reduce cost, time, and effort for analysis; improve quality, reliability, and accuracy of results; and enable scientists to access new scientific capabilities. Successful completion of the proposed work will enable broad dissemination of NWB to neuroscience labs and researchers and integration of NWB with neuroscience tools, providing the research community with an accessible data standard and software ecosystem that enhances utilization, sharing, quality, reliability, and analysis of neurophysiology data.

项目概要 缺乏神经生理学数据和相关元数据的标准是充分利用神经生理学数据的最大障碍。 从神经生理学实验中获取投资回报。科学中最伟大的问题之一 今天的主题是了解大脑如何工作并产生思想、记忆、感知和 意识。为了应对这一挑战，NIH BRAIN 计划和周围的神经生理学家 世界各地进行实验来测量大脑不同部位的神经元活动并将其联系起来 活动到感觉和行为。 BRAIN 计划的一个关键组成部分是支持分享这些丰富的信息 数据集并通过在实验室内部和跨实验室重复使用数据来扩展其价值。该提案的目标是 传播作为 NIH 一部分开发的神经数据无国界 (NWB) 神经生理学技术 BRAIN Initiative 广泛应用于神经科学研究界。 NWB 是一家屡获殊荣的 社区驱动的神经生理学数据标准和软件生态系统。为了促进数据共享和 重用，NWB 格式标准化了神经生理学数据和相关元数据的存储方式，以及 NWB 软件使研究人员能够轻松高效地访问和保存 NWB 格式的数据。一些 领先的神经科学实验室和机构现在在 NWB 中生成数据；然而，巨大的能量壁垒 实验室仍有待标准化其数据。为了降低采用 NWB 的障碍，我们提出了多方面的建议 计划通过关注 1) 神经科学研究人员和实验室的需求，使 NWB 更易于使用 加强新​​技术的用户培训、支持和覆盖；2) 神经科学工具和 通过维护核心 NWB 技术并与各种强大的数据工具集成 和技术。以 NWB 数据为目标，科学家可以使用通用的方法访问、管理和共享数据 协议，而开发人员有一个通用的格式，可以在此基础上构建工具。针对这两个领域 同时，我们的目标是减少分析成本、时间和精力；提高质量、可靠性和准确性 结果;并使科学家能够获得新的科学能力。成功完成拟议工作 将使 NWB 广泛传播给神经科学实验室和研究人员，并将 NWB 与 神经科学工具，为研究界提供可访问的数据标准和软件 增强神经生理学数据的利用、共享、质量、可靠性和分析的生态系统。