THE CONTRIBUTION OF INFLAMMATION AND INSULIN RESISTANCE

炎症和胰岛素抵抗的作用

• 批准号: 7719318
• 负责人: MARK A CREAGER
• 金额: $ 0.05万
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-04-01 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7719318
• 关键词: Atherosclerosis; Blood Vessels; Cells; Computer Retrieval of Information on Scientific Projects Database; Development; Funding; Glucose; Grant; Inflammation; Institution; Insulin Resistance; Muscle; Pain in lower limb; Purpose; Research; Research Personnel; Resources; Source; Symptoms; United States National Institutes of Health; Vascular blood supply; Walking; irritation

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to determine whether inflammation, an irritation of the blood vessel wall and the inability of cells to properly use glucose for energy promote the development of atherosclerosis and worsen symptoms of muscular leg pain with walking because the blood supply to these muscles is inadequate.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 本研究的目的是确定炎症、血管壁刺激以及细胞无法正确利用葡萄糖获取能量是否会促进动脉粥样硬化的发展，并加重步行时肌肉腿部疼痛的症状，因为这些肌肉的血液供应不足是不够的。