Implementation Science and Health Outcomes Core

实施科学与健康成果核心

• 批准号: 10090641
• 负责人: Denis Nash
• 金额: $ 23.17万
• 依托单位: NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC
• 依托单位国家: 美国
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-09-30 至 2023-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10090641
• 关键词: AIDS clinical trial group; AIDS prevention; AIDS/HIV problem; Address; Adherence; Affinity; Africa South of the Sahara; Area; Biomedical Technology; Caring; Cities; Clinical Research; Clinical effectiveness; Collaborations; Community Health Systems; Consultations; Continuity of Patient Care; Diagnosis; Discipline; Doctor of Medicine; Doctor of Philosophy; Effectiveness; Epidemic; Epidemiologist; Epidemiology; Evidence based intervention; Fostering; Funding; Gap Junctions; Geographic Locations; HIV; HIV diagnosis; Health; Health Policy; Healthcare Systems; Institutes; Intervention; Link; Mental Health; Mental disorders; Mentors; Modeling; New York; Outcome; Policies; Policy Analysis; Policy Maker; Population Analysis; Prevention; Prophylactic treatment; Psychiatrist; Psychiatry; Public Health; Research; Research Design; Research Infrastructure; Research Personnel; Science; Scientist; Structure; Testing; Time; Translations; United States National Institutes of Health; Universities; Viral; Vulnerable Populations; behavioral study; behavioral/social science; career; clinical center; comorbidity; economic evaluation; effectiveness implementation study; effectiveness research; evidence base; health disparity; implementation intervention; implementation research; implementation science; improved; innovation; interdisciplinary collaboration; interest; low and middle-income countries; novel strategies; population based; population health; practice setting; pre-exposure prophylaxis; prevent; programs; research study; scale up; screening; substance use; uptake; working group

Although millions of lives have been saved by new biomedical technologies and expansion of prevention and treatment in low- and middle-income countries, many vulnerable people – including in the US – are not benefiting from these advances. Implementation science (IS) research can maximize public health impact by addressing suboptimal implementation of evidence-based strategies; identifying ways in which health care systems and policies fail to adequately address the HIV prevention and care continua; and identifying population-based strategies to improve HIV outcomes in the US and globally. The Implementation Science and Health Outcomes (ISHO) Core will address the HIV Center's overall theme by catalyzing innovative IS research that identifies and tests strategies to optimize “real-world” uptake and impact of effective HIV prevention and care continua interventions at scale. The Core has three Specific Aims: (1) to stimulate new IS research and collaborations to improve key outcomes along the HIV prevention and care continua; (2) to advance new IS research to prevent or reduce HIV-related health disparities that are driven by suboptimal intervention implementation or by psychiatric and other comorbidities; and (3) to promote the use of health policy analysis, policy modeling, and economic evaluation to bridge the evidence-practice and evidence-policy gaps that drive suboptimal population-based implementation and disparities. The ISHO Core will accomplish its Aims through functions that include (1) providing expert consultation to HIV Center researchers on conducting IS research that (a) both tests new approaches to improve HIV-related programmatic outcomes and assesses causes of successful and un-successful implementation of interventions and policies at scale, and (b) incorporates the perspectives of policy translation, policy modeling, and economic evaluation into their research; (2) developing Scientific Working Groups to provide structured and focused guidance to (and collaboration with) Center investigators interested in or embarking on IS through dynamic small groups organized around specific themes (e.g., PrEP implementation, psychiatric comorbidities); (3) facilitating access to linked networks for HIV Center investigators addressing IS-related research questions; and (4) sponsoring seminars to stimulate the use of IS approaches in research. The proposed Core Director, Denis Nash, Ph.D., is an epidemiologist and Director of the Institute for Implementation Science in Population Health (ISPH) at the City University of New York. Core Co-Director, Milton Wainberg, M.D., is a research psychiatrist at the New York State Psychiatric Institute and Columbia University Department of Psychiatry. Together they have extensive expertise in NIH-funded research and capacity building for HIV and mental health treatment and prevention. The Core brings together early stage, mid-career, and established investigators in the areas of IS, health-disparities, and economic evaluation with policy-makers and program implementers to provide an infrastructure for research collaboration.

尽管新的生物医学技术已经挽救了数百万的生命和预防的扩展 以及低收入和中等收入国家的治疗，包括美国在内的许多脆弱人物不是 从这些进步中受益。实施科学（IS）研究可以通过 解决基于证据的策略的次优实施；确定医疗保健的方式 系统和政策无法充分解决艾滋病毒的预防和护理仍在继续；并确定 基于人群的策略，以改善美国和全球的艾滋病毒结局。实施科学 健康结果（ISHO）核心将通过催化创新性来解决艾滋病毒中心的整体主题 确定和测试策略以优化“现实世界”的吸收和有效艾滋病毒的影响的研究 预防和护理继续大规模干预。核心具有三个特定的目标：（1）刺激新的是 研究和合作，以改善HIV预防和护理Continua的关键结果； （2）至 Advance New是预防或减少由次优驱动的与HIV相关的健康差异的研究 干预实施或精神病和其他合并症； （3）促进健康的使用 政策分析，政策建模和经济评估，以弥合证据实践和证据策略 驱动基于人群的实施和分布的差距。 Isho Core将通过包括（1）提供专家咨询的功能来实现其目标 HIV中心的进行进行的研究是（a）两种测试的新方法以改善与HIV相关的相关方法 成功实施干预措施的程序成果和评估原因 和大规模的政策，（b）结合了政策翻译，政策建模和 经济评估他们的研究； （2）开发科学工作组以提供结构化和 专注的指导（并与）有兴趣或开始的中心调查员是通过 围绕特定主题组织的动态小组（例如，准备实施，精神病学 合并症）； （3）支持访问与艾滋病毒中心调查人员有关的链接网络的访问 研究问题； （4）赞助半手赛，以刺激研究中的使用方法。 拟议的核心主任丹尼斯·纳什（Denis Nash）博士是该研究所的流行病学家兼董事 纽约市城市大学的人口健康科学（ISPH）。核心联合导演， 医学博士Milton Wainberg是纽约州精神病学研究所和哥伦比亚的研究精神病医生 大学精神病学系。他们在NIH资助的研究和 艾滋病毒和心理健康治疗和预防的能力建设。核心汇集了早期舞台， 职业中期，并在IS，健康区域和经济评估领域的研究人员与 政策制定者和计划实施者为研究合作提供基础架构。