University of Washington Developmental AIDS Research Center for Mental Health (UW ARCH)

华盛顿大学心理健康发展艾滋病研究中心 (UW ARCH)

• 批准号: 10260314
• 负责人: Jane M. Simoni
• 金额: $ 74.97万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-04-01 至 2025-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10260314
• 关键词: AIDS prevention; Acquired Immunodeficiency Syndrome; Address; Behavioral Sciences; Caring; Clinical; Communities; Complex; Consultations; Country; County; Development; Discrimination; Disease Management; Dissemination and Implementation; Epidemic; Epidemiology; Geography; Goals; HIV; HIV risk; Healthcare; High Prevalence; Incidence; Infrastructure; Intervention; Leadership; Learning; Measurement; Medical; Mental Depression; Mental Health; Mental Health Services; Mental disorders; Mentors; Mentorship; Methods; Mission; Modeling; Pathway interactions; Patients; Poverty; Practice based research; Prevention; Prevention strategy; Primary Health Care; Process; Provider; Research; Research Design; Research Methodology; Research Personnel; Research Support; Resources; Risk; Science; Services; Statistical Methods; Strategic Planning; Substance Use Disorder; Substance abuse problem; Symptoms; Technology; Testing; Training; Training Programs; Trauma; Underrepresented Populations; United States; Universities; Vulnerable Populations; Washington; Work; antiretroviral therapy; base; collaborative care; comorbidity; disparity reduction; driving force; effective therapy; evidence base; experience; health care delivery; healthcare community; implementation science; innovation; marginalized population; mortality; multidisciplinary; next generation; novel; person centered; psychologic; scale up; social science research; social stigma; socioeconomic disadvantage; theories; therapy development; traumatic stress; treatment strategy; user centered design

OVERALL ABSTRACT The proposed University of Washington (UW) Developmental AIDS Research Center (D-ARC) responds to the global HIV epidemic at a critical stage. Though more than 21 million people around the world receive antiretroviral therapy, the most marginalized populations continue to experience high incidence, less access to effective prevention and care, and greater mortality. Unmet needs persist in high-prevalence countries as well as “geographic hotspots” in the US such as Seattle's King County. Intersecting stigma, trauma, poverty, and substance abuse increase risk for mental illnesses, yet the effective treatments available are rarely implemented. The proposed D-ARC aims to address these challenges by catalyzing research that helps end the epidemic, with a focus on integrating care for mental disorders into HIV prevention and treatment strategies. Furthermore, Center investigators will support and apply the science of dissemination and implementation, with the overall goal of bringing such interventions to scale. The D-ARC aims to fill a gap in HIV behavioral science research at UW by capitalizing on the considerable strengths of UW's HIV expertise and bridging this with UW's longstanding leadership in the development and delivery of models of integrated mental health care. By combining UW expertise in (a) HIV research and (b) mental health care—now siloed geographically, programmatically, and conceptually—the Center will be a synergistic force capable of realizing is mission of Implementing Innovative Impactful Integrated Interventions. The proposed infrastructure capitalizes on the strengths of local expertise and broad ties with global collaborative networks, adding value to UW through the Center's administration, research support, and training missions, buttressed through additional institutional commitments of $762,296. Cross-cutting themes of the D-ARC are (a) leveraging local and global bidirectional pathways to learning and innovation by engaging communities of providers and (b) addressing inequities by testing research solutions that reduce disparities. Four proposed Cores address the Overall specific aims: 1) Catalyze and support innovative and impactful research to curb the HIV epidemic, with a focus on integrated intervention strategies (Administrative Core); 2) Provide needed technical assistance and training on research design, measurement, theory and novel statistical methods relevant to mental health and HIV research (Methods Core); 3) Stimulate practice-based research that promotes effective integrated mental health services in HIV care settings and disseminate findings broadly (Integrated Care Core); and 4) Nurture the Next Generation of diverse, multidisciplinary HIV researchers through training and innovative mentorship of early stage investigators and mentors (Developmental Core).

总体抽象 拟议的华盛顿大学（UW）发展艾滋病研究中心（D-ARC）对 全球艾滋病毒在关键阶段流行。虽然世界上有超过2100万人接受抗逆转录病毒 治疗，最边缘化的人群继续遭受高昂的事件，更少获得有效的机会 预防和关怀，以及更大的死亡率。在高额阳性国家以及 美国的“地理热点”，例如西雅图的金县。相交的污名，创伤，贫穷和 滥用药物会增加精神疾病的风险，但很少实施可用的有效治疗方法。 拟议的D-ARC旨在通过催化研究来解决这些挑战 流行病，重点是将精神疾病的护理整合到预防HIV和治疗中 策略。此外，中心调查人员将支持并运用传播科学和 实施，其总体目标是将这种干预措施扩展。 D-ARC旨在填补空白 在UW的艾滋病毒行为科学研究中，通过利用UW艾滋病毒专业知识的考虑优势 并与UW在开发和交付综合模型中的长期领导层桥接这一点 心理保健。通过（a）HIV研究和（b）心理保健的UW专业知识 - 现在是孤立的 从地理上，编程和概念上讲，该中心将是一种能够实现的协同力量 是实施创新有影响力的综合干预措施的使命。拟议的基础设施资本化 关于本地专业知识的优势以及与全球协作网络的广泛联系，从而为UW增值 该中心的政府，研究支持和培训任务，通过其他机构支持 承诺为$ 762,296。 D-ARC的跨切割主题是（a）利用本地和全球双向 通过吸引提供者的社区以及（b）解决不平等的学习和创新途径 测试减少分布的研究解决方案。提出的四个核心解决了总体特定目的：1） 催化和支持创新和有影响力的研究以遏制艾滋病毒的流行，重点是综合 干预策略（行政核心）； 2）提供了研究的技术帮助和培训 与心理健康和艾滋病毒研究有关的设计，测量，理论和新型统计方法（方法） 核）; 3）刺激基于实践的研究，以促进艾滋病毒中有效的综合心理健康服务 护理环境和广泛传播发现（综合护理核心）； 4）培育下一代 潜水员，多学科的艾滋病毒研究人员通过培训和早期研究人员的创新心态 和导师（发展核心）。