Enrichment and Research Administration Core

浓缩和研究管理核心

• 批准号: 10241579
• 负责人: DEAN R MADDEN
• 金额: $ 21.04万
• 依托单位: DARTMOUTH COLLEGE
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-07-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10241579
• 关键词: Achievement; Address; Advisory Committees; Ally; Applications Grants; Area; Award; Basic Science; Biology; Biomedical Research; Clinical; Collaborations; Communication; Communities; Core Facility; Cystic Fibrosis; Data; Decision Making; Doctor of Philosophy; Education; Educational Activities; Educational workshop; Electronic Mail; Ensure; Environment; Epithelial; Expenditure; Extramural Activities; Faculty; Faculty Recruitment; Feedback; Fostering; Foundations; Funding; Goals; Health; Immune response; Immunity; Individual; Infrastructure; Intellectual Property; Interdisciplinary Study; Laboratories; Leadership; Mission; Monitor; National Institute of Diabetes and Digestive and Kidney Diseases; Outcome; Patient-Focused Outcomes; Performance; Pilot Projects; Probability; Process; Productivity; Program Development; Progress Reports; Reporting; Research; Research Activity; Research Personnel; Research Project Grants; Research Support; Research Technics; Resources; Role; Schedule; Series; Services; Structure; Technology Transfer; Therapeutic; Time; Training Activity; Translating; Translational Research; Translations; United States National Institutes of Health; Validation; conflict resolution; cystic fibrosis patients; experience; flexibility; forging; gastrointestinal; gut dysbiosis; high standard; improved; innovation; interest; liver function; meetings; member; microbial colonization; microbial community; novel therapeutic intervention; peer; programs; quality assurance; ranpirnase; recruit; research and development; skills; social media; success; symposium; translational pipeline; web site

The overarching goal of the Enrichment & Research Administration Core (ERAC) is to support the scientific mission of the Dartmouth Cystic Fibrosis Research Center (DartCF): to foster a superior environment for discovery of new principles of CF biology, epithelial function, microbial colonization, and host responses, and their translation into clinical outcomes, in areas of interest to NIDDK. Launched in 2018, DartCF will continue to support three Biomedical Research Cores. It will expand its pilot program to recruit new investigators and fund new research directions, including CF gut dysbiosis, GI microbial communities, and liver function. It will also support an intensive research development program and will leverage institutional resources for program enrichment, including annual symposia and new training modules in best research practices. Working across the basic and translational spectrum, these components will advance the identification and validation of new therapeutic strategies in CF. Scientific leadership will be provided by Director Dean Madden, PhD, the DartCF leadership team, Internal and External Advisory Committees, and an inclusive Faculty Council. The role of the ERAC is to provide efficient scientific leadership, organizational support, and fiscal oversight for all Center components. Building on strategies developed for other programmatic awards and deployed in year one of funding, the ERAC will achieve the following Specific Aims: (1) To provide scientific leadership supporting all DartCF members as they explore new high-impact research directions; (2) To support strategic research development opportunities; (3) To facilitate robust scientific communication; (4) To offer streamlined administrative and fiscal support, providing timely and accurate reporting to DartCF and institutional leadership and NIDDK Program staff; and (5) To enrich the scientific and research environment by deploying institutional resources. Each of these aims will advance the DartCF mission. Inclusive, experienced leadership will identify and create new opportunities for Center faculty to pursue basic and translational research projects in CF, with a goal of improving therapeutic options and patient outcomes. The education program will provide expert guidance to our faculty, enhancing their research productivity and generating additional extramural support for CF research. A weekly research-in-progress series, interspersed with invited seminars and an annual Dartmouth CF Retreat, will sustain a highly integrated, interactive scientific community and stimulate the exploration of new research directions. Together with the Biomedical Research Cores, pilot and core funding will both recruit faculty to the Center and increase their ability to compete for extramural funding. Program leadership has a strong track record of scientific collaboration and two decades' experience with multiproject awards. Leveraging these skillsets, we have developed an Administrative Core committed to providing excellent organizational support to the investigators of DartCF and to advancing its success as an NIDDK-supported CF Research Center.

丰富与研究管理局核心（ERAC）的总体目标是支持科学 达特茅斯囊性纤维化研究中心（DARTCF）的任务：促进一个卓越的环境 发现CF生物学，上皮功能，微生物定殖和宿主反应的新原理以及 他们转化为NIDDK感兴趣领域的临床结果。 DARTCF于2018年推出 支持三个生物医学研究核心。它将扩大其试点计划，以招募新的调查员并资助 新的研究方向，包括CF肠道营养不良，GI微生物群落和肝功能。它也会 支持密集的研究开发计划，并将利用机构资源为计划 充实，包括年度研讨会和最佳研究实践中的新培训模块。工作 基本和翻译频谱，这些组件将推进新的识别和验证 CF的治疗策略。科学领导将由DARTCF院长Dean Madden博士提供 领导团队，内部和外部咨询委员会以及包容性的教职委员会。角色 ERAC将为所有中心提供有效的科学领导，组织支持和财政监督 成分。建立在其他计划奖励的策略的基础上，并在第一年中部署 资金，ERAC将实现以下具体目标：（1）提供支持所有人的科学领导 DARTCF成员在探索新的高影响力研究方向时； （2）支持战略研究 发展机会； （3）促进强大的科学交流； （4）提供精简的 行政和财政支持，向DARTCF和机构领导层提供及时，准确的报告 和NIDDK计划人员； （5）通过部署机构来丰富科学和研究环境 资源。这些目标中的每一个都将推进DARTCF任务。包容性，经验丰富的领导将确定 并为中心教师创造新的机会，以在CF中从事基础和翻译研究项目 改善治疗选择和患者预后的目标。教育计划将为专家提供 对我们教师的指导，提高他们的研究生产力，并为 CF研究。每周进行的研究系列，散布在邀请的研讨会和每年的达特茅斯 CF务虚会，将维持一个高度融合的互动科学界，并刺激对新的探索 研究方向。与生物医学研究核心一起，飞行员和核心资金都将招募教师 到中心，并提高他们争夺校外资金的能力。计划领导力很强 科学合作的记录和二十年的多项目奖励经验。利用这些 技能集，我们已经开发了一个行政核心，致力于提供出色的组织支持 DARTCF的调查人员并促进其作为NIDDK支持的CF研究中心的成功。