Enrichment and Research Administration Core

浓缩和研究管理核心

• 批准号: 10001760
• 负责人: DEAN R MADDEN
• 金额: $ 21.04万
• 依托单位: DARTMOUTH COLLEGE
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-07-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10001760
• 关键词: Achievement; Address; Advisory Committees; Ally; Applications Grants; Area; Award; Basic Science; Biology; Biomedical Research; Clinical; Collaborations; Communication; Communities; Core Facility; Cystic Fibrosis; Data; Decision Making; Doctor of Philosophy; Education; Educational Activities; Educational workshop; Electronic Mail; Ensure; Environment; Epithelial; Epithelium; Expenditure; Extramural Activities; Faculty; Faculty Recruitment; Feedback; Fostering; Foundations; Funding; Goals; Health; Immune response; Immunity; Individual; Infrastructure; Intellectual Property; Interdisciplinary Study; Laboratories; Leadership; Mission; Monitor; National Institute of Diabetes and Digestive and Kidney Diseases; Outcome; Patient-Focused Outcomes; Performance; Pilot Projects; Probability; Process; Productivity; Program Development; Progress Reports; Reporting; Research; Research Activity; Research Personnel; Research Project Grants; Research Support; Research Technics; Resources; Role; Schedule; Series; Services; Structure; Technology Transfer; Therapeutic; Time; Training Activity; Translating; Translational Research; Translations; United States National Institutes of Health; Validation; conflict resolution; cystic fibrosis patients; dysbiosis; experience; flexibility; forging; gastrointestinal; high standard; improved; innovation; interest; liver function; meetings; member; microbial colonization; microbial community; novel therapeutic intervention; peer; programs; quality assurance; ranpirnase; recruit; research and development; skills; social media; success; symposium; translational pipeline; web site

The overarching goal of the Enrichment & Research Administration Core (ERAC) is to support the scientific mission of the Dartmouth Cystic Fibrosis Research Center (DartCF): to foster a superior environment for discovery of new principles of CF biology, epithelial function, microbial colonization, and host responses, and their translation into clinical outcomes, in areas of interest to NIDDK. Launched in 2018, DartCF will continue to support three Biomedical Research Cores. It will expand its pilot program to recruit new investigators and fund new research directions, including CF gut dysbiosis, GI microbial communities, and liver function. It will also support an intensive research development program and will leverage institutional resources for program enrichment, including annual symposia and new training modules in best research practices. Working across the basic and translational spectrum, these components will advance the identification and validation of new therapeutic strategies in CF. Scientific leadership will be provided by Director Dean Madden, PhD, the DartCF leadership team, Internal and External Advisory Committees, and an inclusive Faculty Council. The role of the ERAC is to provide efficient scientific leadership, organizational support, and fiscal oversight for all Center components. Building on strategies developed for other programmatic awards and deployed in year one of funding, the ERAC will achieve the following Specific Aims: (1) To provide scientific leadership supporting all DartCF members as they explore new high-impact research directions; (2) To support strategic research development opportunities; (3) To facilitate robust scientific communication; (4) To offer streamlined administrative and fiscal support, providing timely and accurate reporting to DartCF and institutional leadership and NIDDK Program staff; and (5) To enrich the scientific and research environment by deploying institutional resources. Each of these aims will advance the DartCF mission. Inclusive, experienced leadership will identify and create new opportunities for Center faculty to pursue basic and translational research projects in CF, with a goal of improving therapeutic options and patient outcomes. The education program will provide expert guidance to our faculty, enhancing their research productivity and generating additional extramural support for CF research. A weekly research-in-progress series, interspersed with invited seminars and an annual Dartmouth CF Retreat, will sustain a highly integrated, interactive scientific community and stimulate the exploration of new research directions. Together with the Biomedical Research Cores, pilot and core funding will both recruit faculty to the Center and increase their ability to compete for extramural funding. Program leadership has a strong track record of scientific collaboration and two decades' experience with multiproject awards. Leveraging these skillsets, we have developed an Administrative Core committed to providing excellent organizational support to the investigators of DartCF and to advancing its success as an NIDDK-supported CF Research Center.

浓缩与研究管理核心 (ERAC) 的总体目标是支持科学 达特茅斯囊性纤维化研究中心 (DartCF) 的使命：为 发现 CF 生物学、上皮功能、微生物定植和宿主反应的新原理，以及 它们在 NIDDK 感兴趣的领域转化为临床结果。 DartCF 于 2018 年推出，将继续 支持三个生物医学研究核心。它将扩大试点计划，招募新的研究人员并提供资金 新的研究方向，包括 CF 肠道菌群失调、胃肠道微生物群落和肝功能。它还将 支持密集的研究开发计划，并将利用机构资源来开展该计划 丰富内容，包括年度研讨会和最佳研究实践的新培训模块。跨界工作 基本谱和转化谱，这些组件将促进新的识别和验证 CF 的治疗策略。 DartCF 主任 Dean Madden 博士将提供科学领导 领导团队、内部和外部咨询委员会以及包容性的教师委员会。的作用 ERAC 将为所有中心提供高效的科学领导、组织支持和财政监督 成分。以其他计划奖项制定并在第一年部署的策略为基础 在资金的支持下，ERAC 将实现以下具体目标： (1) 提供科学领导力支持所有 DartCF 成员探索新的高影响力研究方向； （二）支持战略研究 发展机会； (3) 促进强有力的科学交流； (4) 报价精简 行政和财政支持，向 DartCF 和机构领导层提供及时、准确的报告 和 NIDDK 项目工作人员； (5)通过部署机构来丰富科研环境 资源。这些目标中的每一个都将推进 DartCF 的使命。具有包容性、经验丰富的领导力将确定 并为中心教师创造新的机会，在 CF 中开展基础和转化研究项目， 改善治疗选择和患者结果的目标。该教育计划将提供专家 为我们的教师提供指导，提高他们的研究生产力，并为我们的教师提供额外的校外支持 CF 研究。每周一次的正在进行的研究系列，其中穿插着受邀研讨会和一年一度的达特茅斯会议 CF Retreat，将维持一个高度整合、互动的科学社区，并刺激对新事物的探索 研究方向。与生物医学研究核心一起，试点和核心资金都将招募教师 中心并提高他们竞争外部资金的能力。项目领导力有很强的跟踪能力 科学合作的记录和二十年多项目奖项的经验。利用这些 我们开发了一个行政核心，致力于为以下人员提供出色的组织支持： DartCF 的研究人员，并推动其作为 NIDDK 支持的 CF 研究中心的成功。