Data Coordinating and Operations Center for the ECHO IDeA States Pediatric Clinical Trials Network

ECHO IDeA 州儿科临床试验网络数据协调和运营中心

• 批准号: 10240720
• 负责人: Jeannette Y. Lee
• 金额: $ 787.91万
• 依托单位: UNIV OF ARKANSAS FOR MED SCIS
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-23 至 2025-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10240720
• 关键词: Address; Affect; Age; Airway Disease; Area; Arkansas; Award; Biomedical Research; Biometry; Biostatistics Core; Caring; Centers of Research Excellence; Child; Child Care; Child Health; Childhood; Clinical; Clinical Investigator; Clinical Research; Clinical Sciences; Clinical Trials; Clinical Trials Cooperative Group; Clinical Trials Network; Clinical and Translational Science Awards; Conduct Clinical Trials; Data; Data Coordinating Center; Development; Diagnosis; Disease; Dissemination and Implementation; Doctor of Philosophy; Eligibility Determination; Environment; Functional disorder; Funding; Future; Grant; Health; Informatics; Infrastructure; Leadership; Logistics; Medical; Medicine; Mentors; Methodology; Multi-Institutional Clinical Trial; Multicenter Studies; Nebraska; Obesity; Outcome; Patients; Pediatric Research; Physicians; Pilot Projects; Population; Population Distributions; Population Heterogeneity; Prevention; Principal Investigator; Publishing; Randomized Controlled Trials; Recording of previous events; Reporting; Research; Research Activity; Research Institute; Research Personnel; Research Project Grants; Rural; Science; Scientist; Site; Training and Education; Translational Research; United States National Institutes of Health; Universities; Work; base; college; community engagement; data management; design; drug metabolism; evidence base; experience; improved; interest; medically underserved; medically underserved population; member; neurodevelopment; operation; pediatric department; pediatric patients; programs; research and development; rural area; rural underserved; skill acquisition

PROJECT SUMMARY Eligibility for the Institutional Development Award (IDeA) program is based on historically low levels of NIH funding. IDeA states differ from non-IDeA states with respect to the rural/urban distributions of the population and access to medical care. Compared to children in non-IDeA states, children in IDeA states are more likely to live in rural areas and are less likely to have access to or receive medical care. Since multi-center pediatric clinical trial networks are concentrated in centers in non-IDeA states, there are limited opportunities for children living in IDeA states to participate in clinical research activities. The ECHO IDeA States Clinical Trials Network (ISPCTN) was established in 2016 with 17 clinical awardee sites and the Data Coordinating and Operations Center (DCOC) at the University of Arkansas for Medical Sciences (UAMS) in Little Rock, Arkansas. The objectives of the Network are to develop and implement clinical research in the IDeA states in the ECHO priority areas: upper and lower airway disease; obesity; neurodevelopment; pre-, peri-, and post-natal outcomes; and positive child health; and to develop capacity within the IDeA states to conduct clinical trial research. This proposal is for UAMS to continue to serve as the DCOC for the ECHO ISPCTN. The specific aims of the Data Coordination and Operations Center are to 1) Provide scientific, operational, administrative and logistical infrastructure support to the ECHO IDeA States Pediatric Clinical Trials Network (ISPCTN) to facilitate the development, implementation and dissemination of clinical research activities in the ISPCTN; and 2) Build pediatric clinical research capacity in the IDeA states to enhance the potential for conducting clinical trials that address health issues of relevance to children in IDeA states. We will work collaboratively with clinical investigators at the ISPCTN sites, Project Scientists and Project Officers at the NIH ECHO Office, and other participating NIH staff, and collaborating multicenter clinical trials groups to design and implement studies that will address health issues that disproportionately affect rural and medically underserved children.

项目摘要 资格获得机构发展奖（IDEA）计划是基于历史上低水平的NIH 资金。思想状态与非爱德华州在人口的农村/城市分布方面有所不同 并获得医疗服务。与非爱德华州的儿童相比，想法状态中的儿童更有可能 住在农村地区，不太可能获得或接受医疗服务。由于多中心儿科 临床试验网络集中在非IDEA州的中心，儿童的机会有限 生活在思想状态中，参加临床研究活动。 Echo Ideas状态临床试验网络（ISPCTN）于2016年成立，有17个临床获奖者 阿肯色大学医学院的网站以及数据协调与运营中心（DCOC） 阿肯色州小石城的科学（UAMS）。网络的目标是开发和实施 回声优先领域的想法状态的临床研究：上和下气道疾病；肥胖; 神经发育；前，周期和产后结局；和积极的儿童健康；并发展能力 在想法中进行临床试验研究。 该提议是为了使UAM继续充当Echo ISPCTN的DCOC。具体目的 数据协调和运营中心将 1）为回声构想提供科学，运营，行政和后勤基础架构支持 国家小儿临床试验网络（ISPCTN）促进开发，实施和 在ISPCTN中传播临床研究活动；和 2）在想法状态下建立小儿临床研究能力，以增强进行的潜力 临床试验解决了与想法状态中儿童相关的健康问题。 我们将与ISPCTN站点，项目科学家和项目的临床研究人员合作 NIH Echo办公室的官员和其他参与的NIH员工，并合作多中心临床试验 设计和实施研究的小组将解决对农村和农村影响不成比例的健康问题的研究 医疗服务不足的孩子。