The Feasibility and Acceptability of the Mediational Intervention for Sensitizing Caregivers for Mothers with Borderline Personality Disorder

提高边缘性人格障碍母亲照顾者敏感性的调解干预的可行性和可接受性

• 批准号: 10240286
• 负责人: Kiana Cano
• 金额: $ 3.67万
• 依托单位: UNIVERSITY OF HOUSTON
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-01 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10240286
• 关键词: Attitude; Behavior; Borderline Personality Disorder; Caregivers; Child; Child Rearing; Code; Communities; Data; Development; Elements; Exhibits; Feedback; Feeling suicidal; Fellowship; Focus Groups; Future; Goals; Grant; Interruption; Intervention; Interview; Measures; Mental disorders; Mentors; Mentorship; Methods; Modeling; Mothers; National Institute of Mental Health; Outcome; Participant; Pathology; Patient Self-Report; Personality; Persons; Phase; Population; Prevention; Psychopathology; Qualitative Research; Quality of life; Research; Research Personnel; Risk; Sampling; Secure; Structure; Suicide attempt; Testing; Time; TimeLine; Training; Translational Research; acceptability and feasibility; base; completed suicide; design; experience; high risk population; improved; intergenerational; offspring; preference; programs; psychologic; psychosocial; scaffold; targeted delivery; transmission process

Project Summary/Abstract Extant data suggest that the children of mothers with Borderline Personality Disorder (BPD) are at particular risk for a variety of poor psychosocial outcomes, in part because research has demonstrated that mothers with BPD have difficulty forming secure attachment relationships with their children. One avenue for interrupting the intergenerational transmission of psychopathology from mothers to offspring is through scaffolding parenting in mothers. While parenting programs have been developed for most psychiatric disorders, personality pathology has lagged behind. The Mediational Intervention for Sensitizing Caregivers (MISC) has been used in other high-risk populations impacted by attachment disruptions and holds promise for use with mothers with BPD. However, before MISC can be adapted for mothers with BPD, it is first important to evaluate the feasibility and acceptability of MISC for this population. The objective of this application is to use the ADAPT-ITT model to evaluate the feasibility and acceptability of MISC for mothers with BPD and to identify key elements that should be integrated in a future adaptation of MISC for mothers with BPD. The approach of this application will execute the first three steps of the ADAPT-ITT model. Aim 1 (Step 1 of ADAPT-ITT). Quantitative Assessment (phase 1) of attachment and related mechanisms will be conducted with 100 mothers with BPD and 100 mothers without BPD. Qualitative Assessment (phase 2) of parenting and intervention needs will be conducted with 15 mothers with BPD, from phase 1. Aim 2 (Step 2 of ADAPT-ITT model). The Decision to adapt MISC for mothers with BPD will be made by examining the feasibility of MISC for mothers with BPD. Aim 3 (Step 3 of ADAPT-ITT model). Specific intervention targets and delivery features for future Adaptation of MISC will be identified by having the 15 participants from Aim 1-phase 2 participate in theatre testing of MISC. The applications central hypotheses are as follows. Aim 1: Mothers with BPD will exhibit parenting factors which put their children at risk for poor psychosocial outcomes, will have a perceived need for a parenting intervention, and will have specific preferences for treatment targets and delivery. Aim 2: MISC is feasible for mothers with BPD and appropriate for adaptation. Aim 3: MISC is acceptable for mothers with BPD and feedback focus groups will identify specific refinements to MISC’s content, materials and delivery that will need to be incorporated into a future adaptation of MISC. The proposed research is in line with the third strategic objective of the NIMH, the prevention of mental illness. This fellowship will serve as preliminary data for a future F32 or K granted to the PI to adapt MISC materials for use with mothers with BPD. Successful adaptation of MISC- BPD would allow a practical attachment-based intervention to be introduced to the field of personality pathology, potentially improving the quality of life of mothers struggling with BPD and their children. Finally, receiving this fellowship will strengthen the training of a junior researcher as she develops an independent line of translational research, regardless of whether she pursues MISC in particular.

项目摘要/摘要 现有的数据表明，有边缘人格障碍（BPD）的母亲的孩子尤其是 出现各种糟糕的社会心理结局的风险，部分原因是研究表明 BPD很难与孩子建立安全的依恋关系。中断的途径 从母亲到后代的心理病理学的代际传播是通过脚手架的育儿 母亲。在为大多数精神疾病开发了育儿计划时，人格病理学 落后了。敏化护理人员的中介干预措施（MISC）已用于其他 受依恋破坏影响的高风险人群和与BPD母亲一起使用的希望。 但是，在将MISC适应BPD的母亲之前，首先要评估可行性和 杂项对这个人群的可接受性。此应用程序的目的是使用Adapt-Itt模型 评估BPD母亲的MISC的可行性和可接受性，并确定应 将BPD的母亲的杂项改编成未来的改编。该应用程序的方法将 执行Adapt-Itt模型的前三个步骤。 AIM 1（Autapt-Itt的步骤1）。定量评估 （第1阶段）将与100位具有BPD的母亲和100个母亲进行附着和相关机制 没有BPD的母亲。育儿和干预需求的定性评估（第2阶段）将进行 有15位具有BPD的母亲，来自第1阶段。AIM 2（Autapt-Itt模型的步骤2）。改编Misc的决定 患有BPD的母亲将通过检查BPD母亲的MISC的可行性来制作。目标3（步骤3的步骤3 Adapt-Itt模型）。将来适应MISC的具体干预目标和交付功能将是 通过让AIM 1相2的15名参与者参加MISC戏剧测试的参与者来确定。 应用中心假设如下。目标1：BPD的母亲将存在育儿因素 他们的孩子面临不良的社会心理结局的风险，将需要育儿干预的需求， 并将对治疗目标和交付具有特定的偏好。 AIM 2：MISC对有母亲的母亲是可行的 BPD，适合适应。 AIM 3：MISC对于BPD和反馈重点是可以接受的 小组将确定MISC的内容，材料和交付的具体改进，需要 纳入未来的MISC改编。拟议的研究符合第三个战略目标 NIMH，预防精神疾病。该奖学金将作为未来F32或 K授予PI以适应MISC材料，以与BPD的母亲一起使用。成功适应杂项 BPD将允许将基于实用的依恋干预引入个性领域 病理学，有可能改善与BPD及其子女斗争的母亲的生活质量。最后， 接受这项奖学金将加强初级研究人员的培训 转化研究，无论她是否特别追求MISC。