Definition and Caregiver Appraisal of Paradoxical Lucidity in Dementia

痴呆症中矛盾清醒的定义和护理人员评估

基本信息

批准号：
10266123
负责人：
JOAN M. GRIFFIN
金额：
$ 22.79万
依托单位：
MAYO CLINIC ROCHESTER
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-09-30 至 2022-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10266123
关键词：
Address Advocacy Affect Age Alzheimer&apos s Disease Alzheimer&apos s disease related dementia Anecdotes Awareness Behavior Bereavement Brain Health Registry Caregiver well-being Caregivers Case Study Cessation of life Characteristics Clinical Cognitive Communication Conflict (Psychology)Consensus Data Dementia Dementia caregivers Development Dimensions Disease Education Ensure Ethical Issues Event Family Family Caregiver Family member Future Geography Goals Grief reaction Health Impaired cognition Incidence Individual Internet Intervention Interview Knowledge Link Long-Term Care Longitudinal Surveys Measures Memory Methodology Methods Minnesota Mission Moods Nonprofit Organizations Outcome Outcome Study Pattern Persons Pharmaceutical Preparations Phase Prevalence Prognosis Registries Reporting Research Structure Surveys Testing Time Typology Universities Work advocacy organizations base care giving burden caregiver bereavement caregiver interventions caregiving clinical practice cognitive capacity demographics education resources epidemiology study evidence base experience innovation longitudinal analysis novel perceived stress psychoeducation response sex

项目摘要

PROJECT SUMMARY Alzheimer’s disease and related dementias are typically thought of in terms of progressive cognitive decline, and relatively little is known about episodes of lucidity that occur among people with dementia. Paradoxical lucidity is defined as spontaneous, relevant communication or connectedness in a person with dementia. Few studies have focused on paradoxical lucid episodes, and little is known about what may cause paradoxical lucidity, how common lucid events are, and how lucidity impacts family caregivers of persons with dementia. The broad goal of this study is to define paradoxical lucidity, determine the prevalence and predictors of paradoxical lucidity, and assess the impact that lucidity has on family caregivers. Our proposal will establish a definition of paradoxical lucidity based on survey data and interviews with caregivers, as well as input from a panel of clinical experts in Alzheimer’s disease and related dementias. Next, we will administer an online survey to 8,000 dementia caregivers across three time periods (baseline, 6-months, and 12-months) to measure how frequently paradoxical lucidity occurs across time. We will analyze survey data to establish what may predict paradoxical lucidity and how paradoxical lucidity is linked to caregiver well-being. The results of this work will help inform clinical practice, build capacity for Alzheimer’s Disease education and advocacy, and build knowledge on an understudied aspect of dementia.

项目摘要通常，阿尔茨海默氏病和相关痴呆症是从进行性认知能力下降的角度来考虑的关于痴呆症患者中发生的清醒情节的知识相对较少。悖论清晰度定义为痴呆症患者的赞助，相关的交流或联系。很少研究的重点是矛盾的清晰发作，对可能导致悖论的原因知之甚少清醒，清醒事件的常见以及清醒性如何影响痴呆症患者的家庭护理人员。这项研究的广泛目的是定义矛盾的清晰度，确定的患病率和预测因素自相矛盾的清晰度，并评估清醒对家庭护理人员的影响。我们的建议将建立一个根据调查数据和对看护者的访谈以及来自阿尔茨海默氏病和相关痴呆症的临床专家小组。接下来，我们将在线管理在三个时期（基线，6个月和12个月）之间对8,000名痴呆症护理人员进行调查测量矛盾的清晰度在整个时间内发生的频率。我们将分析调查数据以确定什么可以预测矛盾的清晰度，以及矛盾的清除与照料者的福祉有关。结果这项工作将有助于为临床实践提供信息，为阿尔茨海默氏病教育和倡导增强能力，以及建立知识知识的痴呆症方面。