Dermatology Consultation Service

皮肤科咨询服务

基本信息

批准号：
10262802
负责人：
Edward Cowen
金额：
$ 1.09万
依托单位：
DIVISION OF BASIC SCIENCES - NCI
依托单位国家：
美国
项目类别：
财政年份：
资助国家：
美国
起止时间：
至
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10262802
关键词：
Academy Adverse reactions American Angiogenesis Inhibitors Atrial myxoma with lentigines Award Behcet Syndrome Birt-Hogg-Dube Syndrome Bronchiolitis Obliterans Catalogs Chronic Granulomatous Disease Clinical Clinical Research Clinical Research Protocols Clinical Trials Collaborations Communities Congresses Consult Consultations Country Cutaneous Dermatofibrosarcoma Dermatologic Dermatology Diagnosis Disease Dose Enrollment Epidermal Growth Factor Receptor Erlotinib Etiology Fever Folliculitis Goals Hamartoma Hereditary Malignant Neoplasm Heritability Homologous Transplantation Immune Immunologic Deficiency Syndromes Inflammatory Inherited Institutes Interdisciplinary Study Interleukin-1 Interleukin-1 Receptors Interleukin-12 Job&apos s Syndrome Leiomyoma Lesion Lymphoma Malignant Neoplasms Manuscripts Medicine Modality National Human Genome Research Institute National Institute of Allergy and Infectious Disease National Institute of Arthritis and Musculoskeletal and Skin Diseases National Institute of Neurological Disorders and Stroke Natural History Nurse Practitioners Palmar-plantar erythrodysesthesia syndrome Patients Pennsylvania Periodicity Phase Principal Investigator Protocols documentation Publishing Reaction Renal Cell Carcinoma Research Personnel Research Support Rest Rheumatology Services Skin Societies Syndrome Systemic disease Text Therapeutic Therapeutic Trials Transplantation United States National Institutes of Health Variant Wiskott-Aldrich Syndrome adenosine deaminase deficiency anakinra autoinflammatory base bevacizumab chronic graft versus host disease congenital immunodeficiency experience graft vs host disease interest lectures leukemia/lymphoma montelukast pomalidomide response side effect skin disorder skin lesion therapeutic evaluation

项目摘要

The Consult Service Staff consists primarily of myself, Dr. John DiGiovanna and a Nurse Practitioner, Olanda Hathaway, who joined the Branch in 2011. As mentioned above, providing clinical expertise in the assessment and management of the cutaneous disease is a highly valued service to the NIH community which was recognized by the NIH Director's Award in 2007. In addition to seeing patients in Consultation, I am an Associate Investigator on several other protocols initiated by other branches as well as a Principal Investigator on three therapeutic protocols (to be discussed separately). The current non-Dermatology Branch protocols in which I am an Associate Investigator include Natural History of GVHD; Reduced intensity transplants for malignant lymphomas/leukemias; Immune-depleting therapy and reduced intensity transplant using unrelated donors; Allogeneic transplant for DOCK8 Immunodeficiency; Pomalidomide for chronic GVHD; Phase II Montelukast for bronchiolitis obliterans; Erlotinib and bevacizumab for renal cell carcinoma; Natural history of auto-inflammatory diseases; Anakinra for Behcet's disease; Rilonacept for deficiency of the IL-1 antagonist. The chronic graft versus host disease (GVHD) collaborative effort is a major multidisciplinary collaboration with several NCI and non-NCI investigators studying the Natural history of GVHD. Based on my experience with this group, I have published several text chapters and clinical manuscripts on cutaneous GVHD and have been honored to lecture to various groups around the country (Harvard, Tufts, U. of Pennsylvania, the American Academy of Dermatology, regional dermatologic societies, and the World Congress of Dermatology.) Collaborative clinical research is extremely active via the busy consultation service.

咨询服务人员主要由我自己组成，约翰·迪戈瓦纳（John Digiovanna）博士和护士从业者奥兰达·海瑟薇（Olanda Hathaway）于2011年加入该分支机构。 NIH社区在2007年获得NIH董事奖的认可。除了见到咨询患者外，我还是其他分支机构发起的其他几项协议的副研究员，以及针对三种治疗方案的首席研究员（要分别讨论））。当前我是副研究人员的当前非疾病分支方案包括GVHD的自然历史；恶性淋巴瘤/白血病的强度移植降低；免疫缺乏治疗和使用无关供体的强度移植降低； DOCK8免疫缺陷的同种异体移植；慢性GVHD的Pomalidomide；第三阶段的蒙特鲁克斯特（Montelukast）用于细支气管炎；用于肾细胞癌的厄洛替尼和贝伐单抗；自动炎症疾病的自然史；阿纳基纳（Behcet）疾病； Rilonacept缺乏IL-1拮抗剂。慢性移植与宿主疾病（GVHD）的合作努力是与研究GVHD自然历史的几位NCI和非NCI研究人员进行的主要多学科合作。根据我在这个小组的经验，我在皮肤GVHD上发表了几章和临床手稿，并很荣幸向全国各个小组（哈佛，塔夫特，宾夕法尼亚州，美国皮肤病学学院，地区皮肤病学学院）讲授社会和世界皮肤病学大会。）通过繁忙的咨询服务，协作临床研究非常活跃。