Intravitreal Corticosteroid for Macular Edema Study

玻璃体内皮质类固醇治疗黄斑水肿研究

基本信息

批准号：
7616915
负责人：
BARBARA A BLODI
金额：
$ 33.19万
依托单位：
UNIVERSITY OF WISCONSIN-MADISON
依托单位国家：
美国
项目类别：
财政年份：
2003
资助国家：
美国
起止时间：
2003-06-01 至 2010-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7616915
关键词：
Adrenal Cortex Hormones Angiography Area Authorization documentation Blood Vessels Blood capillaries Chairperson Cities Classification Clinic Clinical Clinical Trials Design Collaborations Color Commit Condition Conduct Clinical Trials Data Data Coordinating Center Diabetes Mellitus Diabetic Retinopathy Disclosure Early treatment Eligibility Determination Enrollment Epidemiologic Studies Evaluation Extravasation Face Feedback Fluorescein Fluorescein Angiography Fluoresceins Fundus Fundus photography Human Resources Image Injection of therapeutic agent Instruction Last Name Leadership Letters Light Coagulation Manuscripts Multi-Institutional Clinical Trial Names Numbers Ophthalmology Optical Coherence Tomography Optics Outcome Participant Patient observation Patients Perfusion Pharmacotherapy Phase Preparation Principal Investigator Procedures Protocols documentation Publications Randomized Reading Reporting Research Personnel Research Project Grants Retinal Retinal Vein Occlusion Role Safety Scanning Score Secondary to Thick Tomogram Triamcinolone Acetonide United States Universities Visual Acuity Visual impairment Wisconsin capillary central retinal vein occlusion day density design diabetic experience fovea centralis macular edema programs prospective size stereoscopic vision science

项目摘要

The University of Wisconsin Fundus Photograph Reading Center (UW FPRC) proposes to serve as photograph reading center for the Intravitreal Corticosteroid for Macular Edema study. To accomplish this, we propose to: 1. Apply current procedures for documenting and grading macular edema. We can provide protocols for macular edema imaging (color stereoscopic fundus photographs, fluorescein angiograms, and optical coherence tomograms), and are experienced at orienting, certifying, and giving feedback to clinic photographers. By extending the Early Treatment Diabetic Retinopathy Study classification, we have protocols for evaluation/grading of macular edema from color photographs and fluorescein angiograms. We are developing a protocol for assessment of QCT scans. 2. Assist the study chair and study investigators in 1) the conduct of the clinical trial (for example, timely review of photographs and angiograms for eligibility), 2) the analysis of the resultant data and 3) the preparation of manuscripts for publication. The UW FPRC principal investigator and staff are experienced at participation in collaborative multi-center clinical trials and are strongly committed to the study of new treatments for macular edema due to diabetes mellitus and retinal vein occlusion.

威斯康星大学眼底照片阅读中心 (UW FPRC) 提议作为玻璃体内皮质类固醇治疗黄斑水肿研究的照片阅读中心。为了完成为此，我们建议： 1. 应用当前的黄斑水肿记录和分级程序。我们可以提供协议黄斑水肿成像（彩色立体眼底照片、荧光素血管造影和光学相干断层扫描），并且在定向、认证和向临床提供反馈方面经验丰富摄影师。通过扩展早期治疗糖尿病视网膜病变研究分类，我们制定了根据彩色照片和荧光素血管造影对黄斑水肿进行评估/分级的方案。我们正在开发 QCT 扫描评估协议。 2. 协助研究主席和研究研究者 1) 进行临床试验（例如，及时审查照片和血管造影的资格），2）分析结果数据，3）准备出版手稿。华盛顿大学 FPRC 首席研究员和工作人员在参与协作多中心临床试验方面拥有丰富的经验，并致力于研究黄斑水肿的新疗法由于糖尿病和视网膜静脉阻塞。