Optimization of a new adaptive intervention to increase COVID-19 testing among people at high risk in an urban community

优化新的适应性干预措施，以增加城市社区高危人群的 COVID-19 检测

基本信息

批准号：
10258796
负责人：
Ellen Benoit
金额：
$ 123.91万
依托单位：
UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-05-16 至 2023-11-12
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10258796
关键词：
AIDS prevention Address Adherence Administrative Supplement Age COVID-19 COVID-19 mortality COVID-19 prevention COVID-19 testing COVID-19 treatment COVID-19 vaccination Caring Cessation of life Client Communities Contact Tracing Counseling County Data Development Ethnic Origin Evidence based intervention Exposure to Gender Guidelines HIV Hospitalization Housing Human immunodeficiency virus test Imprisonment Income Individual Intervention Knowledge Low income Medical Neighborhoods New Jersey Occupations Outcome Pamphlets Parents Participant Population Poverty Prevention Prevention Guidelines Provider Public Health Quarantine Race Randomized Recommendation Recording of previous events Research Personnel SARS-CoV-2 infection Sampling Science Sequential Multiple Assignment Randomized Trial Services Sex Bias Site Social Distance Structure Testing United States Urban Community Vulnerable Populations Work adaptive intervention adherence rate base community based participatory research comorbidity cost effective effective intervention ethnic minority population evidence base experience follow-up high risk high risk population housing instability innovation member men multiphase optimization strategy parent grant predictive test prevention service primary outcome public health relevance racial and ethnic racism randomized trial recruit reduced substance use service providers social social health determinants social stigma social vulnerability standard of care substance use success treatment services vaccine access

项目摘要

Project Summary COVID-19 has disproportionately impacted medically or socially vulnerable populations in marginalized urban communities across the United States (e.g., people with co-morbidities, working in high risk settings, those refusing or unable to adhere to the State of New Jersey (NJ) prevention guidelines). Social determinants of health (SDH) such as stigma, incarceration, and poverty are associated with increased exposure to COVID-19 and increased deaths. In the absence of effective, potent, and widely available vaccines and treatments, prevention – i.e., testing, social distancing, contact tracing, and quarantine -- is essential. Little is known about acceptability of COVID-19 testing in low-income and racial/ethnic minority neighborhoods, where residents experience increased barriers to prevention (e.g., inadequate housing, high-risk jobs). However, we have knowledge of cost-effective, evidence-based, and culturally appropriate interventions that have been successfully used to engage people in HIV prevention and treatment. These interventions can be adapted and tested to help address COVID-19. Navigation services (NS) increase HIV testing and adherence to treatment while addressing structural barriers that deter treatment engagement in high-risk communities. Brief counseling increases HIV treatment engagement. This study uses a Sequential, Multiple Assignment Randomized Trial (SMART) with 582 COVID-19 medically/socially vulnerable people. Guided by the COVID-19 Continuum of Prevention, Care, and Treatment, analysis will explore factors associated with testing and adherence to public health recommendations. The study aims include: Aim 1: To optimize an adaptive intervention that will increase rates of testing and adherence to NJ COVID-19 recommendations (testing, social distancing, quarantine, hospitalization, contact tracing and acceptance of COVID-19 vaccination) among high-risk populations. Aim 2: To identify predictors of testing completion and adherence to NJ recommendations. This study is innovative in its application of existing evidence-based interventions to address COVID-19 and the use of SMART following Community Based Participatory Research principles. It has

项目摘要 Covid-19在边缘化的城市中对医学或社会脆弱人群的影响不成比例美国各地的社区（例如，有合并症的人，在高风险环境中工作，拒绝或无法遵守新泽西州（NJ）预防指南）。社会决定者健康（SDH），例如污名，进化和贫困与COVID-19的暴露有关并增加了死亡。在没有有效，潜力和广泛可用的疫苗和处理的情况下预防 - 即测试，社会距离，接触跟踪和隔离 - 至关重要。对在低收入和种族/族裔少数民族社区中的Covid-19测试可接受性，居民经验增加了预防障碍（例如住房不足，高风险工作）。但是，我们有了解经济高效，基于证据和文化适当的干预措施成功用来吸引人们进行艾滋病毒预防和治疗。这些干预措施可以适应，并且经过测试以帮助解决Covid-19。导航服务（NS）增加艾滋病毒测试和遵守治疗同时解决确定高风险社区治疗参与的结构性障碍。简短的咨询增加艾滋病毒治疗参与。本研究使用顺序的多个分配随机试验（智能）与582 Covid-19在医学/社会上脆弱的人。在COVID-19的指导下预防，护理和治疗，分析将探索与公众测试和遵守相关的因素健康建议。该研究的目的包括：目标1：优化适应性干预措施提高测试率和遵守NJ Covid-19的建议（测试，社会疏远，高风险中的隔离，住院，接触跟踪和接种疫苗接种）人群。目标2：确定测试完成的预测指标，并遵守NJ建议。这项研究是针对现有的基于证据的干预措施来解决Covid-19和-19和使用智能的基于社区的参与研究原则。它有