Core D: Special Populations

核心 D：特殊人群

• 批准号: 10256007
• 负责人: CURT G BECKWITH
• 金额: $ 32.02万
• 依托单位: RHODE ISLAND HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-01 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10256007
• 关键词: Accident and Emergency department; Address; Area; Centers of Research Excellence; Certificate of Confidentiality; Clinical Research; Clinical Trials Data Monitoring Committees; Clinics and Hospitals; Communities; Consultations; Course Content; Criminal Justice; Disadvantaged; Education and Outreach; Ethics; Evidence based treatment; Face; Faculty; Goals; Healthcare Systems; Hospitals; Imprisonment; Individual; Infrastructure; Institution; Institutional Review Boards; Interdisciplinary Study; Jail; Mediation; Medical; Mentors; Mission; Opioid; Overdose; Participant; Perinatal; Perinatal Care; Persons; Pharmaceutical Preparations; Population; Pregnant Women; Preparation; Prisoner; Prisons; Protocols documentation; Public Health; Research; Research Assistant; Research Design; Research Personnel; Resources; Rhode Island; Services; Special Population; Stigmatization; Structure; Study Subject; Substance Use Disorder; System; Training; Training Activity; Translational Research; Underserved Population; Universities; Vulnerable Populations; follow-up; human subject protection; illicit opioid; operation; opioid overdose; opioid treatment program; opioid use disorder; opioid user; overdose prevention; patient population; recruit; research study; substance use; webinar

PROJECT SUMMARY The goal of this proposal is to establish a multi-disciplinary research Center focused on the theme of opioids and overdose. This will necessarily include vulnerable and underserved populations. To support this general goal, the proposed Special Populations Core (SPC) will build infrastructure to recruit and retain vulnerable and underserved individuals, build capacity in the ethical conduct of research with vulnerable populations, and serve as a centralized resource for training and outreach regarding the conduct of research among individuals most impacted by overdose and opioid-related harms. The near-term, primary mission of the SPC is to support Project Leaders to recruit and retain opioid-involved individuals through multiple venues including emergency departments, opioid treatment programs (OTPs), hospital/perinatal offices and criminal justice (CJ) facilities; navigate the ethical considerations of engaging vulnerable populations, apply for Institutional Review Board approval and convene data safety monitoring boards. The long-term goal of the SPC is to build a sustainable resource to support the practical challenges posed when working with vulnerable and underserved populations across Rhode Island hospital networks and Brown and other local Universities and research institutions. The SPC will provide an array of services and expertise including: facilitating access to patient populations, providing research staff trained in best practices of recruitment and retention and negotiating various recruitment settings, guidance in human subjects protection and regulatory oversight of research conducted among vulnerable populations, and broaden the community of researchers addressing this critical public health issue through outreach and training in these topics, including the critical overlap of CJ involved populations, opioid use disorders and overdose. Dr. Curt Beckwith and Dr. Timothy Flanigan will be the faculty leaders of this Core. They will provide area expertise in working with CJ and substance using populations. Dr. Janette Baird, Scientific Advisor, will provide area expertise in research conducted among individuals with substance use disorders (SUD) in hospital Emergency Departments and Dr. Caron Zlotnick, Scientific Advisor, will provide area expertise in working with pregnant women with SUD. Michelle McKenzie, MPH, Core Manager, will oversee routine operations, manage Core resources, and provide area expertise in recruitment, tracking and follow-up of SUD populations. Ms. Martino, Training Coordinator, will focus on developing educational forum specific to the incarcerated setting. Two Research Assistants will provide recruitment and retention support for Project Leaders.

项目摘要 该建议的目的是建立一个以阿片类药物为主题的多学科研究中心 和用药过量。这必然包括脆弱和服务不足的人群。支持这一将军 目标，拟议的特殊人群核心（SPC）将建立基础架构，以招募和保留脆弱的人和 服务不足的人，在脆弱人群的研究道德行为中建立能力，以及 作为有关个人进行研究的培训和推广的集中资源 受到过量和阿片类药物相关的危害的影响最大。 SPC的近期主要任务是支持 通过多个地点在内 部门，阿片类药物治疗计划（OTP），医院/围产期办公室和刑事司法（CJ）设施； 涉及参与脆弱人群的道德考虑，申请机构审查委员会 批准并召集数据安全监控板。 SPC的长期目标是建立可持续性 资源以支持与脆弱和服务不足的人群合作时提出的实际挑战 整个罗德岛医院网络以及布朗以及其他当地大学和研究机构。这 SPC将提供一系列服务和专业知识，包括：促进患者人群的访问， 为研究人员提供培训，以招募和保留的最佳实践和谈判各种 招聘环境，人类受试者的指导和对进行研究的监管监督 在弱势群体中，扩大了研究人员的社区，以解决这一关键的公共卫生 通过在这些主题中进行的宣传和培训问题，包括CJ的关键重叠涉及人群， 阿片类药物使用障碍和过量。 Curt Beckwith博士和Timothy Flanigan博士将成为该核心的教职员工。他们将提供区域 使用人群使用CJ和物质方面的专业知识。科学顾问Janette Baird博士将提供 在医院中有药物使用障碍（SUD）进行研究的领域专业知识 紧急部门和科学顾问Caron Zlotnick博士将提供与领域的专业知识 有SUD的孕妇。 MPH，核心经理Michelle McKenzie将监督常规操作，管理 核心资源，并提供领域的专业知识，以招募，跟踪和随访SUD人群。多发性硬化症。 培训协调员马蒂诺（Martino）将着重于开发针对被监禁环境的教育论坛。 两名研究助理将为项目负责人提供招聘和保留支持。