PCORE (Partnership Community Outreach, Research, and Education Core)

PCORE（合作伙伴社区外展、研究和教育核心）

• 批准号: 10250473
• 负责人: Jennifer CF Leng
• 金额: $ 15.12万
• 依托单位: SLOAN-KETTERING INST CAN RESEARCH
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-26 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10250473
• 关键词: Address; American Cancer Society; Area; Behavior; Cancer Center Support Grant; Cardiovascular Diseases; Centers for Disease Control and Prevention (U.S.); Chinese People; Chronic Disease; Clinical; Communities; Community Health; Community Health Education; Community Outreach; Diagnosis; Diet; Doctor of Philosophy; Early Diagnosis; Education; Education and Outreach; Face; Faculty; Funding; Galanin; Health; Health Information System; Health Services Accessibility; Home; Human Papilloma Virus-Related Malignant Neoplasm; Human Papillomavirus; Immigrant; Incidence; Infrastructure; Latino; Lead; Life Style; Linguistics; Malignant Neoplasms; Medical; Memorial Sloan-Kettering Cancer Center; Methodology; Mexican; Minority; Modeling; Needs Assessment; New York City; Obesity; Occupational Groups; Occupations; Outcome; Outreach Research; Patients; Physical activity; Play; Policies; Policy Research; Population; Population Heterogeneity; Poverty; Prevention; Primary Prevention; Provider; Quality of Care; Recommendation; Research; Research Activity; Research Personnel; Resource Sharing; Risk; Risk Factors; Role; Screening for Prostate Cancer; Secondary Prevention; Services; Social Medicine; South Asian; Students; Tobacco; Translational Research; Translations; Treatment outcome; Underrepresented Minority; Work; anticancer research; cancer health disparity; cancer prevention; cancer risk; clinical trial enrollment; colorectal cancer screening; community engaged research; community engagement; community partnership; disparity reduction; education research; evidence base; health care availability; health disparity; high school; improved; improved outcome; individualized prevention; medical schools; medically underserved; member; outreach; personalized immunotherapy; physical conditioning; precision medicine; precision oncology; professor; program dissemination; programs; ranpirnase; recruit; screening; socioeconomics; stem; underserved community; working group

One in three U.S. residents, over 100 million people, are minorities. Over 39 million are foreign-born. New York City (NYC) is home to 3 million foreign-born. Among foreign-born New Yorkers, 48.8% are limited English proficient (LEP), 27.8% did not graduate from high school, and 19.8% are living in poverty. This large and diverse population faces significant disparities in cancer incidence, diagnosis, treatment, and outcomes. These disparities are fueled by health information and systems access barriers, and by an inadequate evidence-base, which stems from insufficient representation in research and program implementation. These factors limit the bi-directional translation of discoveries between bench, patient, community, and policy levels. Over the past 10 years, the PCORE (Partnership Community Outreach-Research-Education) Core has implemented trailblazing community-engaged outreach and research, and addressed socioeconomic determinants of health and gaps in cancer outcomes and quality of care for large underserved communities, including the CCNY community, the Harlem community in which CCNY is embedded, and the broader NYC community. Through partnerships and model program dissemination, PCORE has also extended its activities across the U.S., and is a vital member of several NCI and American Cancer Society Committees addressing the inclusion of diverse populations in research. Over the next 5 years, PCORE will further grow the robust community-academic U54 partnership and infrastructure for community-engaged outreach and translational research. PCORE has the following two Specific Aims: AIM 1. To build upon and strengthen PCORE's community-academic partnership assets to further develop, implement, systematically disseminate and sustain effective community-engaged cancer disparities reduction outreach, community and provider education, service, policy, and research activities to address socioeconomic determinants (centering on health care access) of cancer outcomes and decrease disparities in five priority areas (determined by community-engaged needs assessments and guided by the NCI Blue Ribbon Panel): a) Clinical trials enrollment, including in precision medicine/precision prevention and immunotherapy activities; b) Colorectal cancer screening, and treatment access and completion; c) HPV prevention, and screening for HPV-associated cancers; d) Prostate cancer screening, treatment access and completion; and e) Cancer risk factors including tobacco, obesity, diet, physical activity, and occupation. AIM 2. To build the capacity of researchers and community members to engage the community in the conduct of translational research to reduce cancer disparities, working in concert with the Linguistic and Cultural Responsiveness Shared Resource Core: a) To facilitate community engagement to further enhance and sustain community capacity building, utilizing the extensive network developed by PCORE; b) To support the U54 Partnership Cores, working groups, and projects and to collaborate with the MSK P30 CCSG to engage limited English proficient (LEP) and other diverse populations in their programs and studies.

美国居民超过一亿，三分之一是少数族裔。超过 3900 万人是在外国出生的。纽约 纽约市 (NYC) 拥有 300 万外国出生人口。在外国出生的纽约人中，48.8% 的英语水平有限 精通（LEP），27.8% 没有高中毕业，19.8% 生活贫困。这个大而 不同的人群在癌症发病率、诊断、治疗和结果方面面临着巨大差异。这些 卫生信息和系统获取障碍以及证据基础不足加剧了差异， 这是由于研究和计划实施方面的代表性不足。这些因素限制了 在工作台、患者、社区和政策层面之间双向转化发现。过去10年 多年来，PCORE（伙伴社区外展-研究-教育）核心实施了开创性的 社区参与的外展和研究，并解决健康的社会经济决定因素和差距 大型服务不足社区的癌症结果和护理质量，包括 CCNY 社区、 CCNY 所在的哈莱姆社区以及更广泛的纽约市社区。通过合作伙伴关系和 作为示范计划传播，PCORE 还将其活动扩展到了美国各地，并且是重要成员 多个 NCI 和美国癌症协会委员会致力于将不同人群纳入其中 研究。未来 5 年，PCORE 将进一步发展强大的社区学术 U54 合作伙伴关系 以及社区参与的外展和转化研究的基础设施。 PCORE有以下两种 具体目标： AIM 1. 建立并加强 PCORE 的社区学术伙伴关系资产，以 进一步制定、实施、系统传播和维持有效的社区参与癌症 减少差异的外展活动、社区和提供者的教育、服务、政策和研究活动 解决癌症结果的社会经济决定因素（以医疗保健的获取为中心）并减少 五个优先领域的差异（由社区参与的需求评估确定并由 NCI 指导） 蓝带小组）：a）临床试验注册，包括精准医学/精准预防和 免疫治疗活动； b) 结直肠癌筛查以及治疗的获得和完成； c) HPV HPV 相关癌症的预防和筛查； d) 前列腺癌筛查、治疗获取和 完成； e) 癌症风险因素，包括烟草、肥胖、饮食、体力活动和职业。目标2。 培养研究人员和社区成员的能力，让社区参与到 与语言和文化领域合作，减少癌症差异的转化研究 响应性共享资源核心：a) 促进社区参与，以进一步增强和 利用 PCORE 开发的广泛网络维持社区能力建设； b) 支持 U54 合作伙伴核心、工作组和项目，并与 MSK P30 CCSG 合作，参与 英语水平有限 (LEP) 和其他不同人群的项目和研究。