(2/2) TUFCCC/HC Regional Comprehensive Cancer Health Disparity Partnership

(2/2) TUFCCC/HC 区域综合癌症健康差异伙伴关系

• 批准号: 10248416
• 负责人: Joel Erblich
• 金额: $ 100.87万
• 依托单位: HUNTER COLLEGE
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-18 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10248416
• 关键词: Advanced Malignant Neoplasm; African; African American; Area; Asian Pacific American; Asians; Behavioral; Bioinformatics; Biomedical Research; Biometry; Cancer Burden; Cancer Center; Cancer Control; Clinical; Collaborations; Colorectal Cancer; Communities; Community Networks; Community Outreach; Core Facility; Development; Doctor of Philosophy; Early Diagnosis; Early treatment; Education; Evaluation; Faculty; Fox Chase Cancer Center; Funding; Goals; Hispanic Americans; Human Resources; Incidence; Infrastructure; Institution; Joints; Leadership; Malignant Neoplasms; Malignant neoplasm of liver; Malignant neoplasm of lung; Malignant neoplasm of prostate; Mentors; Minority; Minority Groups; New Jersey; New York City; Not Hispanic or Latino; Outreach Research; Peer Review; Pennsylvania; Phase; Pilot Projects; Population; Positioning Attribute; Prevalence; Program Development; Publications; Recording of previous events; Regional Cancer; Research; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Scientist; Series; Special Population; Students; Training Programs; Underrepresented Minority; Underrepresented Students; Underserved Population; Universities; anticancer research; cancer health disparity; cancer prevention; cancer therapy; cancer type; career; career development; cohesion; college; community based participatory research; education planning; education research; experience; faculty mentor; graduate student; health disparity; health equity; innovation; interest; malignant breast neoplasm; member; mortality; multidisciplinary; organizational structure; programs; racial and ethnic; racial and ethnic disparities; recruit; translational scientist; treatment research; undergraduate student; underrepresented minority student; underserved minority

PROJECT SUMMARY Overall TUFCCC: Grace X. Ma, PhD (Contact PI) and Jean-Pierre Issa, MD (MPI) HC: Olorunseun O. Ogunwobi, MD, PhD (Contact PI) and Joel Erblich, PhD, MPH (MPI) Despite advances in early detection and treatment of cancer, significant racial/ethnic disparities exist in African, Asian-Pacific, and Hispanic Americans, bearing disproportionate cancer burden. These cancer health disparities are particularly salient in the Pennsylvania-New Jersey-New York City (PNN) region, where there is a high concentration of minority populations compared to elsewhere in the U.S. Moreover, despite numerous academic institutions conducting biomedical research in PNN region, there is a critical dearth of underrepresented minorities (URMs) involved in cancer research, who bring unique scientific and cultural strengths necessary to conquer cancer health disparities. Building on collaborative history, successful and synergistic planning activities/accomplishments between TUFCCC and HC, and NCI-funded cancer disparities research networks (CNPC), we propose to establish TUFCCC/HC Regional Comprehensive Cancer Health Disparities Partnership to reduce cancer health disparities in PNN region. The goals of this Partnership are to: a) develop a strong and sustainable collaborative cancer health equity research infrastructure, b) support the development of outstanding URM students and ESIs who are committed to careers in cancer research, and c) collaboratively engage the community in enhancing quality and feasibility of these efforts. These goals will be achieved through the following specific aims: Aim 1. Create and enhance sustainable cancer disparity research collaborations in URM populations between TUFCCC and HC. Aim 1a. Enhance institutional cancer research capacity at HC in basic, behavioral and clinical cancer research and provide HC researchers with access to cancer core facilities, resources and expertise at TUFCCC. Aim 1b. Increase the number of research projects at TUFCCC that focus on cancer health disparities in underserved populations throughout the PNN region. Aim 2. Provide research education opportunities in cancer disparities to support a pipeline of diverse and URM undergraduate and graduate students at HC and TUFCCC. Aim 3. Establish a sustainable career development program to increase the number and diversity of investigators/ESIs to conduct cancer and cancer disparity research at both HC and TUFCCC. Aim 4. Use a Community-Based Participatory Research approach to engage researchers, students and community leaders to develop and implement culturally appropriate collaborative cancer outreach, research and education initiatives to increase access to, and utilization of cancer prevention, early detection and treatment in underserved disparity populations. To achieve U54 goals/aims, the Partnership includes two innovative and rigorous full research projects, a pilot project and a series of integrated cores, including Research Education, Planning and Evaluation, Community Outreach, and Biostatistics/Bioinformatics. Administrative Core will provide oversight and cohesion to the Partnership. Finally, the Partnership has a high level of institutional commitments from both TUFCCC and HC and is well positioned to make significant contributions to advancing cancer health equity in PNN region and beyond.

项目摘要 全面的 TUFCCC：Grace X. MA，博士（联系PI）和Jean-Pierre Issa，医学博士（MPI） HC：Olorunseun O. Ogunwobi，医学博士，博士（联系PI）和Joel Erblich，PhD，MPH（MPI） 尽管在癌症的早期发现和治疗方面取得了进步，但在非洲仍存在明显的种族/种族差异， 亚洲太平洋和西班牙裔美国人，承受不成比例的癌症负担。这些癌症健康 在宾夕法尼亚州 - 新泽西纽约市（PNN）地区，差距尤为明显 而且，与美国其他地方相比，尽管有很多 在PNN地区进行生物医学研究的学术机构，严重缺乏 参与癌症研究的代表性不足的少数民族（URM），他们带来了独特的科学和文化 征服癌症健康差异所需的优势。以协作历史为基础，成功和 TUFCCC和HC之间的协同计划活动/成就，以及NCI资助的癌症差异 研究网络（CNPC），我们建议建立TUFCCC/HC区域综合癌症健康 减少PNN地区癌症健康差异的差异伙伴关系。这种伙伴关系的目标是： a）开发强大，可持续的协作癌症健康公平研究基础设施，b）支持 致力于从事癌症研究职业的杰出URM学生和ESI的发展，C） 协作使社区提高这些努力的质量和可行性。这些目标将是 通过以下特定目的实现：目标1。创造和增强可持续的癌症差异 TUFCCC和HC之间的URM人群的研究合作。目标1a。增强制度癌 HC在基本，行为和临床癌症研究中的研究能力，并为HC研究人员提供 在TUFCCC获得癌症核心设施，资源和专业知识。目标1B。增加数量 TUFCCC的研究项目集中在整个人群中服务不足的癌症健康差异 PNN区域。目标2。提供癌症差异的研究教育机会，以支持 HC和TUFCCC的多元化和URM本科生和研究生。目标3。建立可持续性 职业发展计划，以增加调查人员/ESI的数量和多样性，以进行癌症和 HC和TUFCCC的癌症差异研究。目标4。使用基于社区的参与性研究 吸引研究人员，学生和社区领袖以在文化上发展和实施的方法 适当的合作癌症宣传，研究和教育计划，以增加获得和 在服务不足的差异人群中利用癌症预防，早期检测和治疗。实现 U54目标/目标，合作伙伴关系包括两个创新和严格的完整研究项目，一个试点项目和 一系列综合核心，包括研究教育，计划和评估，社区外展， 和生物统计学/生物信息学。行政核心将为伙伴关系提供监督和凝聚力。 最后，伙伴关系具有TUFCCC和HC的高度机构承诺，并且很好 在PNN地区及其他地区的促进癌症健康公平方面做出了重大贡献。