Core A: Administrative and Professional Development Core

核心 A：行政和专业发展核心

• 批准号: 10246818
• 负责人: Lucy Liaw
• 金额: $ 61.46万
• 依托单位: MAINEHEALTH
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-01 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10246818
• 关键词: Accounting; Administrator; Advisory Committees; Ants; Area; Benchmarking; Biochemical Pathway; Biomedical Research; Cellular biology; Centers of Research Excellence; Clinical; Collaborations; Communication; Contracts; Core Facility; Counseling; Development; Disease; Doctor of Philosophy; Educational workshop; Ensure; Evaluation; Faculty; Fostering; Goals; Grant; Hand; Health; Histopathology; Information Services; Infrastructure; Institutes; Lead; Leadership; Link; Maine; Medical center; Mentors; Mentorship; Mesenchymal; Mesenchymal Stem Cells; Metabolic; Metabolic Diseases; Methods; Monitor; Neurobiology; Nursing Homes; Obesity; Osteocytes; Osteoporosis; Outcome; Pathway interactions; Pharmaceutical Preparations; Physiology; Pilot Projects; Policies; Principal Investigator; Procedures; Productivity; Program Development; Program Evaluation; Proteomics; Rattus; Regulation; Research; Research Infrastructure; Research Methodology; Research Personnel; Research Project Grants; Resource Development; Resources; Role; Scientist; Services; Signal Transduction; Strategic Planning; Structure; Tissue Differentiation; Tissues; Training; bone loss; career; experience; fracture risk; innovation; insight; lipid biosynthesis; lipidomics; neuroregulation; neurotransmission; novel; organizational structure; programs; relating to nervous system; skeletal; success; tool

The Administrative and Professional Development Core is led by Lucy Liaw and Clifford Rosen, the Principal Investigators of this COBRE program. Our goals as leaders of this COBRE program are to foster and support scientific productivity and collaboration, enhance and coordinate our research infrastructure, seek out and expand scientific expertise, and actively oversee and monitor a professional development program. To accomplish these goals, this Core will 1) provide leadership and scientific expertise in the area of mesenchymal tissue differentiation and signaling and neural interactions in metabolic health and disease, 2) establish a core research group consisting of junior investigators supported by scientific and career mentors, 3) enhance scientific core facilities to support state-of-the-art research methodologies, and 4) administer a collaborative pilot project program. The COBRE consists of four thematically linked projects, and each project leader has two senior research mentors who are experts in the field. Additional advisory networks include an External Advisory Committee consisting of scientific experts and experienced program leaders, and a Steering Committee composed of scientific experts and stakeholders in biomedical research in Maine. Our clinical colleagues at Maine Medical Center will provide translational opportunities and important perspective and guidance on clinical challenges in the areas of metabolic health and disease. To support the advancement of our junior investigators and core facility leaders, we have dedicated professional development resources to support courses, workshops, and an innovative scientist leave program to foster collaboration and training. All of these strategies will support project and core leaders in achieving the benchmarks that are clearly defined within our Center. A robust evaluation program will help promote positive long-term outcomes. The specific aims of this Core and the overall program are: Specific Aim 1. Provide the leadership, governance, and advisory network to establish a new scientific program in mesenchymal progenitor cell biology and neural signaling to gain novel insights into the mechanisms underlying metabolic health and disease. Specific Aim 2. Provide project and mentorship support to launch the careers of promising junior investigators within this scientific program and help ensure their long-term scientific success as independent researchers. Specific Aim 3. Enhance the capabilities of our core facilities to support our COBRE investigators and other institutional and external researchers, and to stimulate innovative research methodologies and new collaborations. Specific Aim 4. Enhance our existing, COBRE-supported pilot project programs to focus on translational opportunities related to metabolic disease.

行政和专业发展核心由露西·利亚（Lucy Liaw）和克利福德·罗森（Clifford Rosen）领导 该山cor计划的主要研究人员。我们作为该山cor计划的领导者的目标是促进 并支持科学生产力和协作，增强和协调我们的研究基础设施， 寻求并扩大科学专业知识，并积极监督和监控专业发展 程序。为了实现这些目标，该核心将为1）在该地区提供领导和科学专业知识 代谢健康和疾病中间充质组织分化，信号传导以及神经相互作用的 2）建立一个由科学和职业支持的初级研究人员组成的核心研究小组 导师，3）增强科学核心设施以支持最先进的研究方法，4） 管理协作试点项目计划。该鞋底由四个主题链接的项目组成， 每个项目负责人都有两名高级研究导师，他们是该领域的专家。其他建议 网络包括由科学专家和经验丰富计划组成的外部咨询委员会 领导者以及由科学专家和生物医学研究利益相关者组成的指导委员会 在缅因州。我们在缅因州医疗中心的临床同事将提供转化机会和 关于代谢健康和疾病领域的临床挑战的重要观点和指导。到 支持我们的初级调查员和核心设施领导者的进步，我们已经致力于 专业发展资源以支持课程，研讨会和创新科学家离开 培养协作和培训的计划。所有这些策略将支持项目和核心领导者 实现我们中心中明确定义的基准。强大的评估计划将有所帮助 促进积极的长期结果。该核心和整体计划的具体目的是： 特定目标1。提供领导，治理和咨询网络来建立新的科学 间充质祖细胞生物学和神经信号传导的程序，以获得对该的新见解 代谢健康和疾病的基础机制。 特定目标2。提供项目和指导支持以启动有前途的初级职业生涯 该科学计划中的研究人员，并有助于确保他们作为独立的长期科学成功 研究人员。 特定目标3。增强我们核心设施的能力支持我们的毛绒调查员和 其他机构和外部研究人员，刺激创新的研究方法和新的方法 协作。 特定目的4。增强我们现有的毛绒支持试点项目计划，以专注于翻译 与代谢疾病有关的机会。