GE Healthcare Discovery MR750 3T MRI System

GE Healthcare Discovery MR750 3T MRI 系统

• 批准号: 7839772
• 负责人: Frank Korosec
• 金额: $ 284.87万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-05-06 至 2012-05-05
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7839772
• 关键词: Adult; Alzheimer' s Disease; Anatomy; Arts; Basic Science; Biological Markers; Biomedical Engineering; Blood; Blood Vessels; Brain Mapping; Breast; Cardiovascular system; Cartilage; Cerebrospinal Fluid Pressure; Child; Clinic; Clinical; Collaborations; Commercial Sectors; Deglutition; Development; Diagnosis; Diagnostic; Engineering; Environment; Epilepsy; Exercise; Faculty; Fatty acid glycerol esters; Funding; Future; Gases; Goals; Health Care Costs; Healthcare; Hepatic; Hospitals; Human; Image; Injury; Institutes; Kidney; Kinetics; Lead; Magnetic Resonance Imaging; Malignant Neoplasms; Malignant neoplasm of liver; Maps; Mathematics; Medical; Medical Imaging; Medical Research; Methods; Morphology; Muscle; Names; Occupations; Physics; Radiology Specialty; Recording of previous events; Recycling; Research; Research Activity; Research Personnel; Research Project Grants; Resolution; Resources; Science; Solutions; Stroke; Students; System; Technology; Tongue; Translations; Universities; Water; Wisconsin; cancer imaging; cancer therapy; computer science; human disease; image guided therapy; imaging modality; improved; novel; operation; programs; public health relevance; radiofrequency; reconstruction; research facility; response; treatment planning; treatment response

DESCRIPTION (provided by applicant): The specific aim of this proposal is to obtain funding to purchase a GE Healthcare Discovery MR750 3T Human Whole-Body Magnetic Resonance Imaging (MRI) system to be installed in the Imaging Sciences Center of a newly-constructed, state-of-the-art medical research facility named the Wisconsin Institutes for Medical Research (WIMR) located on the campus of the University of Wisconsin-Madison (UW-Madison). Currently, MRI is the main research focus of more than 70 UW investigators. These investigators comprise a multi-disciplinary group, including faculty, staff, and students from the departments of Medical Physics, Radiology, Biomedical Engineering, Physics, Engineering, Mathematics, Computer Science, and others. The main emphasis of the research is developing new acquisition and reconstruction methods for enhancing the diagnostic capabilities of clinical medical MR imaging in order to improve healthcare worldwide. Current projects focus on rapid imaging, non-Cartesian acquisition trajectories, anatomic vascular imaging, flow imaging of blood and cerebrospinal fluid (CSF), pressure mapping, high temporal resolution imaging of contrast material kinetics, functional brain mapping, primary and secondary liver cancer imaging, hepatic storage imaging, hyperpolarized gas imaging, high spatial resolution breast imaging, high spatial resolution cartilage degradation biomarker imaging, MRI-guided therapy, radiofrequency (RF) transmit/receive coil development, parallel imaging for non-Cartesian acquisition trajectories, anatomic and functional renal imaging, fat and water separation, as well as a host of other topics. In addition to the investigators who perform MR imaging research, there are more than 25 investigators whose research projects rely partially on MRI. These investigators study topics such as treatment planning for cancer, treatment response of cancer, multi-modality image fusion for cardiovascular interventional applications, progression of Alzheimer's disease and its response to therapy, progression of epilepsy in adults and children and its response to therapy, the impact of stroke on swallowing and response to tongue exercises, the effects of injury on muscle morphology and function, and many other medical issues. At UW-Madison, there is a long-standing tradition of inter-departmental and inter-disciplinary collaborations that are necessary for advancing clinical and basic science. The availability of the GE Healthcare Discovery MR750 3T MRI system, conveniently located in a research facility, connected to the hospital, and devoted strictly to research activities, will provide a valuable and necessary resource for the rapid advancement of MRI research projects that will lead to enhanced understanding of human diseases and advances in MR imaging methods and technologies that will provide greater diagnostic capabilities. The goal of the MRI research activities that will be performed on this system is to improve healthcare for all humankind. PUBLIC HEALTH RELEVANCE: Researchers at the University of Wisconsin-Madison have a history of developing novel magnetic resonance imaging (MRI) methods that have led to advances in modern medical imaging and improvements in diagnosing human diseases. Availability of a 3T MRI scanner that is dedicated solely to medical imaging research will: i) accelerate the translation of these methods from the lab to the clinic, ii) permit completion and continuation of existing projects permitting retention of UW faculty, staff, and students, iii) facilitate the acquisition of future funding, making possible retention of current, and recruitment of future, researchers, and iv) lead to the development of new features for medical imaging that will provide increased jobs in the commercial sector and may even lead to reductions in healthcare costs. Acquisition of the MR750 has positive impact on the environment, since GE has several "green" solutions such as a refurbishment and recycling program where 94% of materials are reused, redeployed, or recycled, and during operation, the MR750 has low energy requirements and requires very few consumables.

描述（由申请人提供）：该提案的具体目的是获得资金，以购买GE Healthcare Discovery MR750 3T人类全身磁共振成像（MRI）系统，该系统将安装在一个新近建造的，最先进的，最先进的医学研究设施的成像科学中心，名为WISCONTUTES（WIMR），该学院名为Wimr camp camp coucks of the Wimr campus of the Wimr的研究（UW-Madison）。目前，MRI是70多名UW研究人员的主要研究重点。这些研究人员组成了一个多学科小组，包括医学物理学，放射学，生物医学工程，物理，工程，数学，计算机科学等的教职员工和学生。该研究的主要重点是开发新的采集和重建方法，以增强临床医学MR成像的诊断能力，以改善全球医疗保健。当前的项目着重于快速成像，非 - 牙龈习得轨迹，解剖学血管成像，血液和脑脊液的流动成像（CSF），压力映射，对比度材料动力学的高时间分辨率成像，功能性脑映射，功能性大脑映射，一级和次级肝脏癌成像，高度旋转成像，高度旋转量化，高度旋转量化，高度旋转量化，定期固定量，高度旋转量化，定期固定，旋转量化，定期固定，旋转量化，旋转量化，旋转高度固定，定期固定，旋转量化软骨降解生物标志物成像，MRI引导疗法，射频（RF）传输/接收线圈开发，非现行习得轨迹的平行成像，解剖和功能性的肾脏成像，脂肪和水分分离，以及其他主题的宿主。除了进行MR成像研究的研究人员外，还有25多个研究人员的研究项目部分依赖于MRI。这些研究者研究了诸如癌症治疗计划，癌症治疗反应，心血管干预应用的多模式图像融合，阿尔茨海默氏病的进展及其对治疗的反应，成人和儿童癫痫的进展及其对治疗的反应，对吞咽的影响以及对舌头锻炼的影响以及对舌头锻炼的影响，对医学锻炼的影响以及对肌肉的影响以及肌电疗法的影响，并在效果上造成了许多作用，并在效果上造成了摩擦，并在效果上受到了损害。在威斯康星大学麦迪逊分校（UW-Madison），有一种长期以来的部门间和跨学科合作的传统，这些传统对于促进临床和基础科学的前进是必要的。 GE Healthcare Discovery的可用性MR750 3T MRI系统（方便地位于研究机构）与医院相关，并严格致力于研究活动，将为MRI研究项目的快速发展提供有价值的和必要的资源，从而可以增强对人类疾病的了解，并在MR成像方法和技术方面提高了更大的疗法疗法，这些方法将提供更大的疗法。将在该系统上进行的MRI研究活动的目标是改善所有人类的医疗保健。 公共卫生相关性：威斯康星大学 - 麦迪逊分校的研究人员有开发新型磁共振成像（MRI）方法的史，这导致了现代医学成像的进步和诊断人类疾病的改善。仅专门用于医学成像研究的3T MRI扫描仪的可用性将：i）加速这些方法从实验室到诊所的翻译，ii）允许在UW教职员工，员工和学生中保留现有项目的现有项目，允许对未来的资金进行医学领域的发展，并促进未来的领导者，并促进了未来的研究，并促进了未来的招聘者，并促进了未来的招聘人员，并促进了招聘者的发展。成像将为商业部门提供增加的就业机会，甚至可能导致医疗保健成本降低。由于GE具有多种“绿色”解决方案，例如翻新和回收计划，其中94％的材料被重复使用，重新部署或回收，因此MR750的能源需求较低，需要很少的消耗品。