KL2 Training Program

KL2培训计划

• 批准号: 10086537
• 负责人: JESSICA A KAHN
• 金额: $ 83.03万
• 依托单位: UNIVERSITY OF CINCINNATI
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-14 至 2025-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10086537
• 关键词: 3-Dimensional; Abbreviations; Active Learning; Address; American Heart Association; Appointment; Biomedical Research; Biometry; Clinical; Clinical Investigator; Clinical Research; Clinical Sciences; Collaborations; Department of Defense; Development Plans; Direct Costs; Discipline; Educational workshop; Ensure; Faculty; Fostering; Foundations; Funding; Grant; Health; Individual; Inosine Diphosphate; International; Journals; K-Series Research Career Programs; Longevity; Manuscripts; Measures; Medical center; Medicine; Mentors; NCI Scholars Program; Outcome; Pediatric Hospitals; Principal Investigator; Program Development; Program Evaluation; Publishing; Research; Research Design; Research Ethics; Research Personnel; Research Project Grants; Science; Secure; Site; Sum; Training; Training Programs; Translational Research; Translations; Underrepresented Minority; Universities; Woman; Work; Workforce Development; burnout; career; career development; clinical center; college; design; epidemiology study; evidence base; experience; improved; innovation; meetings; method development; next generation; programs; recruit; scale up; skill acquisition; skills; success; translational scientist; translational study

Contact PD/PI: Heubi, James E Inst-Career-Dev-001 (001) I. INSTITUTIONAL CAREER DEVELOPMENT CORE (KL2 PROGRAM) ABSTRACT The University of Cincinnati Center for Clinical and Translational Science and Training (CCTST) has an excellent record of accomplishment in training KL2 Scholars. The KL2 program has appointed 24 Scholars (50% women, 12.5% underrepresented) from diverse disciplines since 2009 (2 per year, for 2- to 3-year appointments). Scholars have published a total of 674 manuscripts and presented 792 abstracts and workshops at national and international scientific meetings. Of the 20 graduates, 95% are still conducting Clinical and Translational Research (CTR) and 100% have served as Principal Investigator (PI) or Co- Investigator (Co-I) of an externally-funded CTR grant: 20% have transitioned to PI of a career development award (CDA), 65% to PI of a federal independent grant, 75% to PI of a CDA or federal independent grant, and 95% to PI or Co-I of a federal independent grant. Graduates have served as PI of 7 R01s, 3 independent Department of Defense grants, 4 R21s, 1 R03, 2 R40s, 1 R25, 1 R15, 1 U19, 2 K23s, 1 K25, and 1 American Heart Association CDA. They have served as site PI of 3 U01s. The sum of direct costs generated by Scholars’ grants is $109,286,934. Our team has increasingly appreciated the need to address the challenges to developing junior researchers, including: 1) recruiting and developing diverse investigators; 2) training them to be competent in a broad spectrum of core CTR skills; 3) preparing them to successfully conduct team science; 4) ensuring that they achieve sustainable and independent careers; 5) fostering vitality (professionally engaged, committed, and fulfilled) despite increasing levels of burnout among academic faculty; and 6) encouraging them to integrate stakeholder priorities in research and disseminate research to improve health outcomes. As a result, we have designed our KL2 Scholars program to address these challenges using evidence-based strategies, to achieve the following Specific Aims: 1) Train the next generation of clinical and translational investigators through mentored research experiences, core methods and skills development, and tailored experiential learning opportunities; 2) Develop engaged, diverse junior investigators who have sustainable translational research careers; and 3) Promote the translation of Scholar research into improved health outcomes across the lifespan. We have planned several new collaborations across CTSA hubs and a number of innovations that can be scaled up to include other hubs, using the 3D (develop, demonstrate and disseminate) approach. We have designed a rigorous program evaluation plan including NCATS common metrics, have incorporated broad training in research ethics, and have developed a comprehensive plan to increase the recruitment and retention of investigators who are underrepresented in biomedical research. Success will be measured by the following outcomes: 1) we recruit diverse, vibrant Scholars, 2) Scholars secure grants and publish work in high-impact journals; 3) Scholars develop sustained, independent research careers; and 4) Scholars’ research results in improved health outcomes. Commonly-Used Abbreviations: AHC – Academic Health Center; BERD – Biostatistics, Epidemiology, and Research Design; CCHMC – Cincinnati Children’s Hospital Medical Center; CCTST – Center for Clinical and Translational Science and Training; CDA – Career Development Award; CIS – Center for Improvement Science; CTR – Clinical and Translational Research; IDP – Individual Development Plan; OAACD – Office of Academic Affairs and Career Development; PTC – Pilot Translational and Clinical Studies Core; TWD – Translational Workforce Development; UCCOM – University of Cincinnati College of Medicine; URM – Underrepresented Minority Page 915 Project Summary/Abstract Contact PD/PI: Heubi, James E Inst-Career-Dev-001 (001) Narrative The NCATS KL2 career development programs are foundational to developing the next generation of clinical and translational researchers and ensuring that they achieve career success and research independence. The University of Cincinnati Center for Clinical and Translational Science and Training has a strong record of accomplishment in training KL2 Scholars: of the 20 graduates, 95% are still conducting clinical and translational research, 100% have served as Principal Investigator or Co-Investigator of an externally-funded grant, and the sum of direct costs generated by Scholars’ grants I $109,286,934. We propose to 1) train the next generation of clinical and translational investigators through mentored research experiences, core methods and skills development, and tailored experiential learning opportunities; 2) develop engaged, diverse junior investigators who have sustainable translational research careers; and 3) promote the translation of Scholar research into improved health outcomes across the lifespan, through innovative training strategies. Page 916

联系 PD/PI：Heubi, James E Inst-Career-Dev-001 (001) I. 机构职业发展核心（KL2 计划） 抽象的 辛辛那提大学临床和转化科学与培训中心 (CCTST) 在培养 KL2 学者方面取得了优异的成绩 KL2 计划已任命了 24 名学者。 （50% 为女性，12.5% 代表性不足）自 2009 年以来来自不同学科（每年 2 名，持续 2 至 3 年） 学者们共发表论文674篇，提交摘要792篇 在 20 名毕业生中，95% 仍在举办国家和国际科学会议的研讨会。 临床和转化研究 (CTR) 且 100% 曾担任首席研究员 (PI) 或联合研究员 外部资助的 CTR 资助的研究员 (Co-I)：20% 已转型为职业 PI 开发奖 (CDA)，65% 给予联邦独立资助的 PI，75% 给予 CDA 或联邦的 PI 独立资助，95% 授予联邦独立资助的 PI 或 Co-I 毕业生曾担任 PI。 7 架 R01、3 架独立国防部拨款、4 架 R21、1 架 R03、2 架 R40、1 架 R25、1 架 R15、1 架 U19、2 架 K23、1 架 K25 和 1 个美国心脏协会 CDA 担任 3 个 U01 的现场 PI 的直接成本总和。 我们的团队越来越认识到解决这一问题的必要性。 初级研究人员面临的挑战，包括：1）招募和培养多样化的研究人员； 2) 培训他们掌握广泛的核心 CTR 技能 3) 为他们的成功做好准备； 进行团队科学；4）确保他们实现可持续和独立的职业生涯；5）培养活力； （专业投入、奉献和成就感）尽管学术人员的倦怠程度不断增加； 6) 鼓励他们将利益相关者的优先事项纳入研究并传播研究成果以改进 因此，我们设计了 KL2 学者计划来应对这些挑战。 基于证据的策略，以实现以下具体目标：1）培训下一代临床和 通过指导研究经验、核心方法和技能发展来转化研究者，以及 量身定制的体验式学习机会； 2) 培养敬业、多元化的初级研究人员 可持续的转化研究事业；3) 促进学术研究转化为改进的成果 我们计划在 CTSA 中心和一个中心开展多项新的合作。 使用 3D（开发、演示和 我们设计了严格的计划评估计划，包括 NCATS 通用方法。 指标，纳入了广泛的研究伦理培训，并制定了一项全面的计划 增加生物医学研究中代表性不足的研究人员的招募和保留。 成功将通过以下结果来衡量：1）我们招募多元化、充满活力的学者，2）学者 获得资助并在高影响力期刊上发表作品；3) 学者开展持续、独立的研究； 4) 学者的研究成果改善了健康状况。 常用缩写：AHC – 学术健康中心；BERD – 生物统计学、流行病学和 研究设计；CCHMC – 辛辛那提儿童医院医疗中心；CCTST – 临床和治疗中心 转化科学与培训；CDA——职业发展奖；CIS——改进中心 科学；CTR – 临床和转化研究；IDP – 个人发展计划； 学术事务和职业发展；PTC – 试点转化和临床研究核心； 转化劳动力发展；UCCOM – 辛辛那提大学医学院 – 代表性不足的少数群体 第 915 页 项目概要/摘要 联系 PD/PI：Heubi, James E Inst-Career-Dev-001 (001) 叙述 NCATS KL2 职业发展计划是开发下一代临床医生的基础 和转化研究人员，并确保他们取得职业成功和研究独立性。 辛辛那提大学临床和转化科学与培训中心拥有良好的记录 KL2学者培养成果：20名毕业生中，95%仍在从事临床和 转化研究，100%曾担任外部资助的Principal Investigator或Co-Investigator 补助金，以及学者补助金产生的直接费用总和为 109,286,934 美元。我们建议 1) 培训 通过指导研究经验、核心技术培养下一代临床和转化研究人员 方法和技能发展，以及量身定制的体验式学习机会；2) 开发参与性、多样化的学习机会； 具有可持续转化研究生涯的初级研究人员；3) 促进转化 通过创新的培训策略来改善整个生命周期的健康结果的学者研究。 第 916 页