Center for Clinical and Translational Science and Training

临床和转化科学与培训中心

基本信息

批准号：
10613549
负责人：
JESSICA A KAHN
金额：
$ 452.02万
依托单位：
UNIVERSITY OF CINCINNATI
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-08-14 至 2025-03-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10613549
关键词：
Abbreviations Address Adult Area Award Basic Science Biometry Body mass index Center for Translational Science Activities Child Clinical Clinical Investigator Clinical Research Clinical Sciences Clinical Trials Clinical and Translational Science Awards Collaborations Communities Data Data Science Development Dissemination and Implementation Education Educational process of instructing Elderly Environment Epidemiology Ethics Ethnic Origin Family Foundations Gender Genomics Goals Grant Health Health system Healthcare Individual Informatics Information Technology Institution Knowledge Learning Longevity Measurable Medical center Medicine Methodology Methods Mission Outcome Participant Patient Care Patient Recruitments Patients Pediatric Hospitals Population Provider Race Research Research Design Research Personnel Resources Science Site Special Population System Time Training Translating Translational Research Translations Underrepresented Minority Universities Workforce Development biomedical informatics clinical center clinical implementation college community engagement data infrastructure data management disparity reduction drug development empowerment experience health care delivery health disparity health outcome disparity improved innovation learning community medical specialties member metropolitan multidisciplinary novel population health practice-based research network programs pyrolytic carbon recruit research to practice success synergism technology development translational engagement translational pipeline translational scientist

项目摘要

Contact PD/PI: Heubi, James E OVERALL ABSTRACT The Center for Clinical and Translational Science and Training (CCTST) was established at the University of Cincinnati (UC) in 2005 and awarded an institutional Clinical and Translational Science Award (CTSA) in 2009. Since that time, basic science research, genomics, technology, and drug development have made remarkable progress, warranting new solutions for translating research to practice. Concurrent with these discoveries, the CCTST has created innovative solutions for our program functions, including biomedical informatics, biostatistics and study design, regulatory and ethics, community engagement and team science, recruitment and support for clinical trials, patient care interactions, pilot grants, and translational workforce development. With the competitive renewal application and the current revision and creation of CCTST 3.0, we will continue to utilize the guiding principles of learning health systems to develop stronger bidirectional relationships with our community and expeditiously bring discoveries to application. Indeed, we intend to capture this tremendous opportunity to better align the clinical/operational mission of the health system with the research mission of the University and its affiliates. The overarching goal of the CCTST is to maximize the impact of clinical and translational research to improve individual and population health locally and nationally, through 1) engaging stakeholders to collaboratively translate research into improved health care practice and community wellness across the lifespan; 2) developing a diverse, multidisciplinary workforce to conduct innovative, team-based, community-engaged translational research and to disseminate and implement findings that will improve health outcomes and reduce disparities; and 3) optimizing the use of biomedical data across the translational research continuum using innovative data science methods to advance discovery, dissemination, and implementation. For each of the programs and optional functions, these aims serve as the basis for planned innovative activities and to facilitate cross-core integration. We specifically target learning health systems as an optional module for this application because of the expertise available at Cincinnati Children's Hospital Medical Center that can be leveraged across the CCTST and its health care affiliates. In fulfilling these aims, CCTST 3.0 will catalyze the translation of discoveries into improved health outcomes locally and nationally. Page 307 Project Summary/Abstract Contact PD/PI: Heubi, James E NARRATIVE The CTSA consortium has matured to the point that 57 sites are working together to advance science with the goal to improve the health of the nation. The University of Cincinnati Center for Clinical and Translational Science and Training has become a portal of entry for clinical and translational investigators to obtain support for the completion of their studies across the spectrum of translational science, from the bench to population health. With this revised renewal application, we will develop additional innovative methods to produce high quality research, share these discoveries, collaborate with other CTSA hubs, and have a measurable impact on the health of our community using the principles of a learning health system. Page 308

联系PD/PI：Heubi，James E 全面的抽象的临床与转化科学与培训中心（CCTST）是在大学的辛辛那提（UC）于2005年颁发了2009年的机构临床和转化科学奖（CTSA）。自那时以来，基础科学研究，基因组学，技术和药物开发变得非凡进步，保证将研究转化为实践的新解决方案。与这些发现同时发生 CCTST为我们的计划功能创建了创新的解决方案，包括生物医学信息学，生物统计学和研究设计，监管和道德，社区参与和团队科学，招聘并支持临床试验，患者护理互动，试点赠款和转化劳动力发展。随着竞争性更新应用以及CCTST 3.0的当前修订和创建，我们将继续利用学习卫生系统的指导原则，与我们的社区，并迅速将发现提出应用。确实，我们打算捕捉这一巨大的更好地使卫生系统的临床/运营使命与研究使命大学及其分支机构。 CCTST的总体目标是最大化临床和翻译研究以通过1）参与来改善本地和全国范围内的个人和人口健康利益相关者合作将研究转化为改进的医疗保健实践和社区健康整个生命周期； 2）开发多样化的多学科劳动力，以开展创新的，基于团队的劳动力社区参与转化研究并传播和实施将改善健康的发现结果并减少差异； 3）优化在翻译中的生物医学数据的使用使用创新数据科学方法进行研究，以提高发现，传播和执行。对于每个程序和可选功能，这些目标是计划的基础创新活动并促进跨核心整合。我们专门针对学习卫生系统作为该应用程序的可选模块是因为辛辛那提儿童医院提供的专业知识可以在CCTST及其医疗保健分支机构中利用的中心。在实现这些目标时，CCTST 3.0将催化发现在当地和全国范围内改善健康结果的转化。第307页项目摘要/摘要联系PD/PI：Heubi，James E 叙述 CTSA财团已经成熟到57个地点正在共同努力，以推进科学改善国家健康的目标。辛辛那提大学临床与翻译中心科学和培训已成为临床和转化调查人员获得支持的入口为了完成他们在翻译科学领域的研究，从板凳到人口健康。通过此修订的续订应用，我们将开发其他创新方法来产生高质量研究，分享这些发现，与其他CTSA枢纽合作，并具有可衡量的影响关于我们社区的健康，使用学习卫生系统的原则。第308页