Nicaraguan Emerging and Endemic Diseases (NEED) Training Program

尼加拉瓜新发和地方病 (NEED) 培训计划

• 批准号: 10117048
• 负责人: Sylvia Irene Becker-Dreps
• 金额: $ 24.6万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-05-10 至 2023-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10117048
• 关键词: Accreditation; Address; Affect; Bilateral; Biomedical Research; Calicivirus; Caribbean region; Chikungunya virus; Childhood; Dengue; Diarrhea; Disease Outbreaks; Doctor of Philosophy; Endemic Diseases; Enrollment; Ensure; Faculty; Fostering; Growth; Infectious Disease Epidemiology; Influenza; Institution; Interdisciplinary Study; Latin America; Lung diseases; Mentors; Microbiology; Morbidity - disease rate; Nicaragua; Nicaraguan; North Carolina; Pattern; Prevalence; Public Health; Research; Research Personnel; Research Project Grants; Research Training; Respiratory syncytial virus; Risk; Science; Scientist; Serotyping; Training; Training Programs; Universities; Viral Epidemiology; Virus; Virus Diseases; Yellow fever virus; Zika Virus; biomedical scientist; burden of illness; cohort; design; evidence base; faculty research; innovation; laboratory experience; low and middle-income countries; mortality; pathogen; pathogenic virus; population health; pre-doctoral; programs; skill acquisition; skills; success

Contact PD/PI: Becker-Dreps, Sylvia Abstract t The growing, global impact of emerging and endemic viral diseases is a critical public health issue. The explosive spread of zika virus throughout Latin America and the Caribbean in 2015 followed only two years after a similar pattern of spread of chikungunya virus. In 2017, yellow fever virus from Amazon regions emerged in Rio de Janeiro, underscoring the risk of a major urban outbreak. In addition to these emerging and reemerging viruses, endemic viruses continue to cause a high burden of disease. Caliciviruses are now the leading causes of childhood diarrhea in Nicaragua, influenza and respiratory syncytial virus continue to cause a high burden of respiratory disease, and all four dengue serotypes are now endemic. We have designed a program to train a cadre of innovative scientists in Nicaragua to confront these emerging and endemic pathogens of high priority to the LMIC institution. The rationale for this program is to protect the public health of populations by increasing the numbers and expertise of local scientists to 1) describe the epidemiology of these viral pathogens, 2) understand their impact on morbidity and mortality, and 3) identify evidence-based approaches to reduce their prevalence and burden of disease. The Nicaraguan Emerging and Endemic Diseases (NEED) Training Program takes advantage of the convergence of a longstanding relationship between Universidad Nacional Autónoma de Nicaragua, León (UNAN-León) and the University of North Carolina at Chapel Hill (UNC), existing collaborative research for trainee projects, and strong bilateral institutional support. The program’s objectives include: 1) Provide long-term, pre-doctoral training in infectious disease epidemiology at UNC to two young investigators from UNAN-León. These graduates will contribute to the core research faculty at UNAN-León to address pressing local research agendas; 2) Create a sustainable supply of well-trained biomedical scientists in the region by establishing an accredited PhD program in Biomedical Sciences at UNAN- León; we will enroll five pre-doctoral candidates in the initial cohort. This program builds upon a successful Master’s program of Microbiology in place at UNAN-León and fills a huge need in Nicaragua for rigorous PhD- level biomedical research training. We further support five of these pre-doctoral trainees for one-month long laboratory trainings at UNC. 3) Foster professional growth and research skills development among 140 trainees of all levels, including local faculty, to ensure academic and research success. Robust short-term trainings in professional and research skills needed to become an independent investigator and successful academician are provided to both trainees and local faculty to ensure that the program’s impacts extend more broadly. This program will result in a multidisciplinary research team at UNAN-Leon to confront the emerging and endemic viral diseases that affect public health both regionally and globally. Our approach is made feasible by leveraging an existing successful Master’s program at UNAN-León and by providing trainees the opportunity to partner with mentors at both UNC and UNAN-León on a growing array of collaborative research projects.

联系PD/PI：Sylvia Becker-Dreps 抽象的 t 新兴和内在病毒疾病的日益增长的全球影响是一个关键的公共卫生问题。爆炸性 Zika病毒在2015年在拉丁美洲和加勒比海地区的传播之后仅两年 基孔肯雅病毒的传播模式。 2017年，亚马逊地区的黄热病病毒出现在里约热内卢 Janeiro强调了重大城市爆发的风险。除了这些新兴和重新出现的病毒外， 内在病毒继续引起疾病的高燃烧。鞘病毒现在是 尼加拉瓜的儿童腹泻，影响者和呼吸系统病毒继续引起高燃烧 呼吸道疾病和所有四种登革热血清型现在都是内在的。我们设计了一个程序来训练A 尼加拉瓜的创新科学家的干部面对这些新兴和高度优先的内在病原体 LMIC机构。该计划的理由是通过增加人口的公共健康 当地科学家的数字和专业知识至1）描述这些病毒病原体的流行病学，2）了解 它们对发病率和死亡率的影响，以及3）确定基于证据的方法来降低其患病率 和疾病烧伤。尼加拉瓜新兴和地方性疾病（需要）培训计划 NacionalAutónomade大学长期关系的融合的优势 尼加拉瓜，莱昂（Unan-León）和北卡罗来纳大学教堂山（UNC），现有合作 学员项目的研究和强大的双边机构支持。该计划的目标包括：1） 向UNC提供长期的传染病流行病学培训，向两个年轻人提供 Unan-León的调查人员。这些毕业生将为Unan-León的核心研究学院做出贡献 解决当地研究议程的问题； 2）创建可持续训练的生物医学供应 该地区的科学家在Unan-An- 莱昂；我们将在初始队列中注册五名博士前候选者。该程序以成功的方式建立 在Unan-León制定了硕士学校的微生物学计划，并满足了尼加拉瓜的巨大需求 水平生物医学研究培训。我们进一步支持其中的五个预科学员长达一个月 UNC的实验室培训。 3）促进140的专业成长和研究技能发展 包括当地教师在内的各个层面的学员，以确保学术和研究成功。强大的短期 专业和研究技能的培训需要成为独立研究者和成功的培训 向学员和地方教师提供院士，以确保该计划的影响扩大了更多 广泛。该计划将导致Un-Leon的多学科研究团队与新兴 以及在区域和全球影响公共卫生的内在病毒疾病。我们的方法是可行的 通过利用Unan-León的现有成功硕士课程，并为学员提供机会 与UNC和Unan-León的导师合作，共同越来越多的合作研究项目。