Nicaraguan Emerging and Endemic Diseases (NEED) Training Program

尼加拉瓜新发和地方病 (NEED) 培训计划

• 批准号: 9884834
• 负责人: Sylvia Irene Becker-Dreps
• 金额: $ 24.62万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-05-10 至 2023-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9884834
• 关键词: Accreditation; Address; Affect; Bilateral; Biomedical Research; Calicivirus; Caribbean region; Chikungunya virus; Childhood; Dengue; Diarrhea; Disease Outbreaks; Doctor of Philosophy; Endemic Diseases; Enrollment; Ensure; Faculty; Fostering; Growth; Infectious Disease Epidemiology; Influenza; Institution; Interdisciplinary Study; Latin America; Lung diseases; Mentors; Microbiology; Morbidity - disease rate; Nicaragua; Nicaraguan; North Carolina; Pattern; Prevalence; Public Health; Research; Research Personnel; Research Project Grants; Research Training; Respiratory syncytial virus; Risk; Science; Scientist; Serotyping; Training; Training Programs; Universities; Viral Epidemiology; Virus; Virus Diseases; Yellow fever virus; Zika Virus; biomedical scientist; burden of illness; cohort; design; evidence base; faculty research; innovation; laboratory experience; low and middle-income countries; mortality; pathogen; pathogenic virus; population health; pre-doctoral; programs; skill acquisition; skills; success

Contact PD/PI: Becker-Dreps, Sylvia Abstract t The growing, global impact of emerging and endemic viral diseases is a critical public health issue. The explosive spread of zika virus throughout Latin America and the Caribbean in 2015 followed only two years after a similar pattern of spread of chikungunya virus. In 2017, yellow fever virus from Amazon regions emerged in Rio de Janeiro, underscoring the risk of a major urban outbreak. In addition to these emerging and reemerging viruses, endemic viruses continue to cause a high burden of disease. Caliciviruses are now the leading causes of childhood diarrhea in Nicaragua, influenza and respiratory syncytial virus continue to cause a high burden of respiratory disease, and all four dengue serotypes are now endemic. We have designed a program to train a cadre of innovative scientists in Nicaragua to confront these emerging and endemic pathogens of high priority to the LMIC institution. The rationale for this program is to protect the public health of populations by increasing the numbers and expertise of local scientists to 1) describe the epidemiology of these viral pathogens, 2) understand their impact on morbidity and mortality, and 3) identify evidence-based approaches to reduce their prevalence and burden of disease. The Nicaraguan Emerging and Endemic Diseases (NEED) Training Program takes advantage of the convergence of a longstanding relationship between Universidad Nacional Autónoma de Nicaragua, León (UNAN-León) and the University of North Carolina at Chapel Hill (UNC), existing collaborative research for trainee projects, and strong bilateral institutional support. The program’s objectives include: 1) Provide long-term, pre-doctoral training in infectious disease epidemiology at UNC to two young investigators from UNAN-León. These graduates will contribute to the core research faculty at UNAN-León to address pressing local research agendas; 2) Create a sustainable supply of well-trained biomedical scientists in the region by establishing an accredited PhD program in Biomedical Sciences at UNAN- León; we will enroll five pre-doctoral candidates in the initial cohort. This program builds upon a successful Master’s program of Microbiology in place at UNAN-León and fills a huge need in Nicaragua for rigorous PhD- level biomedical research training. We further support five of these pre-doctoral trainees for one-month long laboratory trainings at UNC. 3) Foster professional growth and research skills development among 140 trainees of all levels, including local faculty, to ensure academic and research success. Robust short-term trainings in professional and research skills needed to become an independent investigator and successful academician are provided to both trainees and local faculty to ensure that the program’s impacts extend more broadly. This program will result in a multidisciplinary research team at UNAN-Leon to confront the emerging and endemic viral diseases that affect public health both regionally and globally. Our approach is made feasible by leveraging an existing successful Master’s program at UNAN-León and by providing trainees the opportunity to partner with mentors at both UNC and UNAN-León on a growing array of collaborative research projects.

联系PD/PI：Sylvia Becker-Dreps 抽象的 t 新兴和特有病毒疾病的全球影响是爆炸性的关键。 Zika病毒在2015年在拉丁美洲和加勒比海地区的传播之后仅在类似之后仅在Twoyears之后 2017年的基孔肯雅病毒的传播模式，来自亚马逊地区的黄热病病毒出现在里约热内卢。 Janeiro除了这些新兴和恢复Viruse之外，还强调了重大城市爆发的风险。 特有病毒计数会导致疾病的高负担。 尼加拉瓜，流感和呼吸同步病毒的儿童腹泻继续造成高负担 呼吸道疾病，现在所有四个四个登革热血清型现在都发出了信号。 尼加拉瓜创新的科学家的干部面对高度兴趣的新兴和流行病原体。 LMIC机构。该计划的理由是通过增加人口 当地科学家的数字和专业知识至1）描述这些病毒病原体的流行病学，2）了解 它们对病人和死亡率的影响，以及3）确定基于证据的方法来降低其患病率 和疾病负担。 NacionalAutónomade De大学长期关系的融合的优势 尼加拉瓜，莱昂（Unan-León）和北卡罗来纳大学教堂山（UNC），Exsting合作 对学员项目的研究和强大的双边机构支持。 在UNC的传染病流行病学上提供长期的，博士前的培训，向两个年轻人提供 这些毕业生的调查人员将为Unan-León的核心研究教师做出贡献 提出当地研究议程； 2）创建可持续的训练生物医学 该地区的科学家在Unan-An- 莱昂（León）;我们将在最初的同类中注册五个前候选人。 在Unan-León制定了微生物学硕士课程，并满足了尼加拉瓜的巨大需求 级别的生物医学研究培训。 实验室培训。3）140 各个层次的学员，包括当地的教师，以确保短期的学术和研究成功 专业和研究技能的培训需要成为独立研究者和成功的培训 向培训和当地人提供院士，以确保该计划的影响延伸 广泛地。 以及对公共卫生的流行病毒疾病在军事上和全球性上都影响公共卫生。 通过利用Unan-León的Exsting成功硕士课程，并提供培训的机会 与UNC和UN-León的导师合作，共同越来越多的合作研究项目。