SEARCH: SMS Electronic Adolescent Reminders for Completion of HPV vaccination- Uganda
搜索:短信电子青少年提醒完成 HPV 疫苗接种 - 乌干达
基本信息
- 批准号:10057829
- 负责人:
- 金额:$ 32.3万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-08-01 至 2023-07-31
- 项目状态:已结题
- 来源:
- 关键词:AbsenteeismAchievementAdolescentAdoptedAfricaAfrica South of the SaharaAfricanCapitalCaregiversCellular PhoneChildChildhoodCitiesClinicCommunitiesDevelopmentDiagnosisDiseaseDoseEffectivenessEnrollmentEventFamilyFemaleFemale AdolescentsFoundationsFrightFutureGovernmentHealthHealth care facilityHouseholdHuman Papilloma Virus VaccinationHuman Papilloma Virus VaccineHuman PapillomavirusImmunizationIncomeInterventionInterviewKnowledgeLanguageLeadershipLogisticsMalignant NeoplasmsMalignant neoplasm of cervix uteriMeasuresMethodsNursesOutcomePaperParentsPatternPerceptionPerformancePhasePlayPolicy MakerPopulationPreventive measurePrimary PreventionProcessPublishingRandomizedRandomized Controlled TrialsResearchRoleSchoolsSeriesSiteSystemTarget PopulationsTelephoneText MessagingTimeTranslational ResearchUgandaVaccinatedVaccinationVaccinesVoiceWomanWorld Bankadolescent healthauthoritybasecontrol trialdesignfeasibility trialgirlsinformantliteracylow and middle-income countriesmembermortalityoutreachpilot trialpreadolescenceprogramsprototypepublic health relevancesuburbusual care armvaccine safety
项目摘要
Cervical cancer is the leading female cancer in Uganda. Many women are diagnosed with late-stage
disease, and 80% of women die within 5 years of diagnosis, making primary prevention critical. HPV is the
principal cause of cervical cancer, making vaccination the single most important primary preventive measure.
The national HPV vaccination program in Uganda began in November 2015 and focuses solely on
preteen/adolescent girls. Two strategies have been adopted for the multi-dose series: 1) school-based and 2)
community-based. However, in Kampala, only 29% of girls receive both needed doses. Reasons for under
vaccination include school absenteeism on special vaccination days for those receiving vaccination as part of a
school program, failing to remember to come to a health facility for a needed dose for those being vaccinated
in the community, and lack of knowledge regarding HPV and the vaccines including vaccine misperceptions.
While research regarding the use of text message vaccine reminders is strong in the U.S., their use has not
yet been demonstrated in a preteen/adolescent population in Sub-Saharan African or other low- and middle-
income countries (LMICs). According to the World Bank, currently 89.9% of urban households in Uganda have
a cell phone. This study will take place at three health centres and their affiliated schools and community
immunization centers overseen by the Kampala Capital City Authority (KCCA) as well as at the
Makerere/Mulago/Columbia Adolescent Health Clinic, also in Kampala. While text messages can be used in
populations with low literacy, families can opt to receive automated phone call reminders instead.
R21: Aim 1: Identify desired HPV vaccine text message reminder content (and parallel automated phone
reminders) using key informant interviews We will conduct formative research using key informant interviews
with stakeholders at each site as well as policy makers. Aim 2: Develop and pretest HPV vaccine reminders
with target population We will share prototypes of the designed messages with families to identify issues with
clarity, tone, and persuasiveness. Aim 3: Pilot assess the impact of vaccine reminders on HPV vaccination We
will randomize caregivers of preteens/adolescents at one KCCA site and the adolescent clinic, stratified by site,
language and HPV vaccine dose needed (initiation vs. completion). Feasibility milestones will include reach,
effect size determination and implementation measures. R33: Aim 4: Conduct a full-scale randomized-control
trial to assess the impact of text message reminders on HPV vaccination We will conduct a full-scale RCT
assessing the impact of the HPV vaccine text message reminders. The main outcome will be timeliness of
vaccination. We will also collect process/feasibility measures. This project, if successful, will provide an
important foundation not only for the use of HPV vaccine text message reminders in Uganda but also for other
childhood and adolescent vaccinations in Uganda and in other LMICs.
宫颈癌是乌干达领先的女性癌症。许多妇女被诊断出患有晚期
疾病和80%的妇女在诊断后的5年内死亡,这使得原发性预防至关重要。 HPV是
宫颈癌的主要原因,使疫苗接种成为最重要的主要预防措施。
乌干达的国家HPV疫苗接种计划始于2015年11月,仅关注
青春期/青少年女孩。多剂量系列已经采用了两种策略:1)基于学校和2个)
基于社区。但是,在坎帕拉,只有29%的女孩接受两种需要的剂量。未来的原因
疫苗接种包括在特殊疫苗接种天的缺席,作为接受疫苗接种的人的一部分
学校计划,未能记住来到医疗机构,以供接受接种疫苗的人所需的剂量
在社区中,以及缺乏有关HPV和包括疫苗误解在内的疫苗的知识。
尽管有关使用短信疫苗提醒的使用的研究在美国很强,但它们的使用尚未
然而,在撒哈拉以南非洲或其他中低点的青春期/青少年人口中得到了证明
收入国家(LMIC)。根据世界银行的数据,目前有89.9%的乌干达城市家庭有
手机。这项研究将在三个卫生中心及其附属学校和社区举行
坎帕拉首都管理局(KCCA)监督的免疫中心以及
Makerere/Mulago/哥伦比亚青少年健康诊所,也在坎帕拉。虽然可以在
识字率低的人群可以选择接收自动电话提醒。
R21:AIM 1:确定所需的HPV疫苗短信提醒内容(以及并行自动化电话
提醒)使用关键的线人访谈,我们将使用关键的线人访谈进行形成性研究
每个站点的利益相关者以及政策制定者。目标2:开发和预测HPV疫苗提醒
与目标人群一起,我们将与家人分享设计信息的原型,以确定与
清晰,语气和说服力。 AIM 3:试点评估疫苗提醒对HPV疫苗接种的影响我们
将在一个KCCA站点和青少年诊所中随机将青少年/青少年的护理人员随机化,并按现场分层
语言和HPV疫苗剂量需要(启动与完成)。可行性里程碑将包括触及到
效果大小确定和实施措施。 R33:AIM 4:进行全尺度随机控制
试验以评估短信对HPV疫苗接种的影响,我们将进行全面的RCT
评估HPV疫苗短信提醒的影响。主要结果将是及时的
疫苗接种。我们还将收集流程/可行性措施。如果成功的话,这个项目将提供
重要的基础不仅用于使用乌干达的HPV疫苗短信提醒,还用于其他
乌干达和其他LMIC的儿童和青少年疫苗接种。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Sabrina Bakeera Kitaka其他文献
Sabrina Bakeera Kitaka的其他文献
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{{ truncateString('Sabrina Bakeera Kitaka', 18)}}的其他基金
SEARCH: SMS Electronic Adolescent Reminders for Completion of HPV vaccination- Uganda
搜索:短信电子青少年提醒完成 HPV 疫苗接种 - 乌干达
- 批准号:
10886152 - 财政年份:2020
- 资助金额:
$ 32.3万 - 项目类别:
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SEARCH: SMS Electronic Adolescent Reminders for Completion of HPV vaccination- Uganda
搜索:短信电子青少年提醒完成 HPV 疫苗接种 - 乌干达
- 批准号:
10886152 - 财政年份:2020
- 资助金额:
$ 32.3万 - 项目类别:
Understanding the role of schools in supporting HIV treatment outcomes among HIV infected adolescents
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10672257 - 财政年份:2020
- 资助金额:
$ 32.3万 - 项目类别: