FASEB's "The Lipid Droplets Conference"

FASEB 的“脂滴会议”

• 批准号: 10064358
• 负责人: ROBERT V FARESE
• 金额: $ 0.4万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-01 至 2021-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10064358
• 关键词: Address; Atherosclerosis; Biochemical; Biochemistry; Biogenesis; Biological Models; Biology; Biophysics; Cardiovascular Diseases; Cells; Cellular biology; Clinical Research; Collaborations; Colorado; Cultured Cells; Development; Diabetes Mellitus; Disabled Persons; Disease; Drosophila genus; Educational workshop; Endocrinology; Energy Metabolism; Epidemic; Equilibrium; Feedback; Fostering; Functional disorder; Funding; Genetic; Genetic Determinism; Goals; Grant; Health; Human; Human Characteristics; Imaging technology; Immunity; Insulin Resistance; International; Lipid Inclusion; Lipids; Lipodystrophy; Lipolysis; Malignant Neoplasms; Medicine; Metabolic Diseases; Metabolic syndrome; Metabolism; Minority; Modeling; Movement; Mus; National Institute of Diabetes and Digestive and Kidney Diseases; Nerve Degeneration; Neurodegenerative Disorders; Non-Insulin-Dependent Diabetes Mellitus; Obesity; Oral; Organ; Organelles; Participant; Pathology; Physiology; Play; Postdoctoral Fellow; Prevalence; Process; Request for Applications; Research; Research Personnel; Scientist; Site; Students; Time; Tissues; Training; Underrepresented Minority; United States National Institutes of Health; Woman; Work; Writing; Yeasts; biophysical properties; career; collaborative environment; design; experience; fly; graduate student; innovation; insight; meetings; microscopic imaging; next generation; non-alcoholic fatty liver disease; novel; novel therapeutic intervention; oxidation; posters; prevent; programs; student training; summer research; symposium; trafficking; tumor metabolism

Project Summary The 7th FASEB Summer Research Conference on Lipid Droplets, entitled “Lipid Droplets in Health and Disease,” will focus on the rapidly developing field of lipid droplet biology. Lipid droplets are dynamic cellular organelles that play key roles in energy metabolism. Lipid droplet accumulation and dysfunction are hallmarks of metabolic diseases, including obesity, lipodystrophy, insulin resistance, diabetes, nonalcoholic fatty liver disease, and cardiovascular disease. They are increasingly being studied in the contexts of cancer metabolism, neurodegeneration and immunity as well. The increasing prevalence of metabolic disorders throughout the world lends increased urgency to encouraging research into fundamental aspects of how lipid droplets form, grow, move, mature, and degrade and how lipid droplets influence cell, tissue and organismal physiology and contribute to disease. Understanding of these concepts is necessary for the rationale design appropriate new therapeutic strategies. The conference will be held from July 5-8, 2020 at the Snowmass Weston Hotel in Snowmass, CO. The format includes an opening night keynote address by Tobias Walther, six sessions of talks by invited speakers, as well as short talks by trainees and early career investigators selected from submitted abstracts, three poster sessions, a Career Workshop on career design and balance, and a Meet the Experts session on advanced imaging microscopy. The meeting format will encourage and facilitate interactions between trainees, early career investigators and established investigators. The scientific sessions cover the full breadth of lipid-droplet biology, from biophysical, biochemical, and cellular topics to physiology and disease. Talks from internationally renowned researchers will span basic to clinical research and describe diverse approaches (biophysics, genetics, biochemistry, cell biology, physiology) and models (mice, humans, cultured cells, flies, yeast). This meeting continues to represent THE major international meeting dedicated exclusively to lipid droplets and remains a unique forum for researchers to exchange ideas and share breaking results in this dynamic and timely field. A central aim of this conference is training and encouraging the next generation of scientists. This application requests funding to support the participation of 14 graduate students, postdoctoral fellows and early career investigators, including women, underrepresented minorities, and persons with disabilities, who will be chosen from submitted abstracts judged as superior. The intimate conference format, the secluded conference site, and the many opportunities for informal interactions between participants, planned and unplanned, will provide young investigators opportunities to present their work, to obtain feedback from leaders in the field, and to get career advice.

项目概要 第七届 FASEB 脂滴夏季研究会议，题为“健康与健康中的脂滴” 疾病》将重点关注快速发展的脂滴生物学领域。脂滴是动态的细胞。 在能量代谢中起关键作用的细胞器是脂滴积累和功能障碍的标志。 代谢性疾病，包括肥胖、脂肪营养不良、胰岛素抵抗、糖尿病、非酒精性脂肪肝 疾病和心血管疾病越来越多地在癌症的背景下进行研究。 代谢、神经退行性变和免疫等代谢紊乱的患病率不断增加。 世界各地越来越迫切地鼓励研究脂质如何产生的基本方面 液滴的形成、生长、移动、成熟和降解以及脂滴如何影响细胞、组织和生物 了解这些概念对于基本原理设计是必要的。 适当的新治疗策略。 会议将于 2020 年 7 月 5 日至 8 日在科罗拉多州斯诺马斯的斯诺马斯韦斯顿酒店举行。 形式包括托比亚斯·瓦尔特 (Tobias Walther) 的开幕之夜主题演讲、特邀演讲者的六场演讲、 以及从提交的摘要中选出的实习生和早期职业调查员的简短演讲、三张海报 会议，关于职业设计和平衡的职业研讨会，以及关于高级的专家会面会议 会议形式将鼓励和促进学员之间的早期互动。 职业研究人员和知名研究人员的科学会议涵盖了脂滴的全部内容。 生物学，从生物物理、生物化学和细胞主题到生理学和疾病。 著名研究人员将涵盖基础研究到临床研究，并描述不同的方法（生物物理学、 遗传学、生物化学、细胞生物学、生理学）和模型（小鼠、人类、培养细胞、果蝇、酵母）。 会议继续代表专门致力于脂滴和脂滴的主要国际会议 仍然是研究人员在这个动态和变化中交流想法和分享突破性成果的独特论坛 及时领域。 这次会议的中心目标是培训和鼓励下一代科学家。 申请请求资金支持 14 名研究生、博士后研究员和早期研究人员的参与 职业调查员，包括妇女、代表性不足的少数族裔和残疾人，他们将 提交的摘要被评为优秀。 亲密的会议形式，隐蔽的会议。 网站，以及许多计划内和计划外的非正式互动机会，将 为年轻研究人员提供展示其工作、获得该领域领导者反馈的机会， 并获得职业建议。