FASEB's "The Lipid Droplets Conference"

FASEB 的“脂滴会议”

• 批准号: 10064358
• 负责人: ROBERT V FARESE
• 金额: $ 0.4万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-01 至 2021-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10064358
• 关键词: Address; Atherosclerosis; Biochemical; Biochemistry; Biogenesis; Biological Models; Biology; Biophysics; Cardiovascular Diseases; Cells; Cellular biology; Clinical Research; Collaborations; Colorado; Cultured Cells; Development; Diabetes Mellitus; Disabled Persons; Disease; Drosophila genus; Educational workshop; Endocrinology; Energy Metabolism; Epidemic; Equilibrium; Feedback; Fostering; Functional disorder; Funding; Genetic; Genetic Determinism; Goals; Grant; Health; Human; Human Characteristics; Imaging technology; Immunity; Insulin Resistance; International; Lipid Inclusion; Lipids; Lipodystrophy; Lipolysis; Malignant Neoplasms; Medicine; Metabolic Diseases; Metabolic syndrome; Metabolism; Minority; Modeling; Movement; Mus; National Institute of Diabetes and Digestive and Kidney Diseases; Nerve Degeneration; Neurodegenerative Disorders; Non-Insulin-Dependent Diabetes Mellitus; Obesity; Oral; Organ; Organelles; Participant; Pathology; Physiology; Play; Postdoctoral Fellow; Prevalence; Process; Request for Applications; Research; Research Personnel; Scientist; Site; Students; Time; Tissues; Training; Underrepresented Minority; United States National Institutes of Health; Woman; Work; Writing; Yeasts; biophysical properties; career; collaborative environment; design; experience; fly; graduate student; innovation; insight; meetings; microscopic imaging; next generation; non-alcoholic fatty liver disease; novel; novel therapeutic intervention; oxidation; posters; prevent; programs; student training; summer research; symposium; trafficking; tumor metabolism

Project Summary The 7th FASEB Summer Research Conference on Lipid Droplets, entitled “Lipid Droplets in Health and Disease,” will focus on the rapidly developing field of lipid droplet biology. Lipid droplets are dynamic cellular organelles that play key roles in energy metabolism. Lipid droplet accumulation and dysfunction are hallmarks of metabolic diseases, including obesity, lipodystrophy, insulin resistance, diabetes, nonalcoholic fatty liver disease, and cardiovascular disease. They are increasingly being studied in the contexts of cancer metabolism, neurodegeneration and immunity as well. The increasing prevalence of metabolic disorders throughout the world lends increased urgency to encouraging research into fundamental aspects of how lipid droplets form, grow, move, mature, and degrade and how lipid droplets influence cell, tissue and organismal physiology and contribute to disease. Understanding of these concepts is necessary for the rationale design appropriate new therapeutic strategies. The conference will be held from July 5-8, 2020 at the Snowmass Weston Hotel in Snowmass, CO. The format includes an opening night keynote address by Tobias Walther, six sessions of talks by invited speakers, as well as short talks by trainees and early career investigators selected from submitted abstracts, three poster sessions, a Career Workshop on career design and balance, and a Meet the Experts session on advanced imaging microscopy. The meeting format will encourage and facilitate interactions between trainees, early career investigators and established investigators. The scientific sessions cover the full breadth of lipid-droplet biology, from biophysical, biochemical, and cellular topics to physiology and disease. Talks from internationally renowned researchers will span basic to clinical research and describe diverse approaches (biophysics, genetics, biochemistry, cell biology, physiology) and models (mice, humans, cultured cells, flies, yeast). This meeting continues to represent THE major international meeting dedicated exclusively to lipid droplets and remains a unique forum for researchers to exchange ideas and share breaking results in this dynamic and timely field. A central aim of this conference is training and encouraging the next generation of scientists. This application requests funding to support the participation of 14 graduate students, postdoctoral fellows and early career investigators, including women, underrepresented minorities, and persons with disabilities, who will be chosen from submitted abstracts judged as superior. The intimate conference format, the secluded conference site, and the many opportunities for informal interactions between participants, planned and unplanned, will provide young investigators opportunities to present their work, to obtain feedback from leaders in the field, and to get career advice.

项目摘要 第七届FaseB夏季脂质液滴研究会议，名为“健康和 疾病，“将重点放在脂质液滴生物学的快速发展领域。脂质液滴是动态细胞 在能量代谢中起关键作用的细胞器。脂质液滴积累和功能障碍是标志 代谢性疾病，包括肥胖，脂肪营养不良，胰岛素抵抗，糖尿病，非酒精脂肪肝 疾病和心血管疾病。在癌症的情况下，他们越来越多地研究 代谢，神经退行性和免疫良好。代谢疾病的患病率不断增加 全世界都提出了迫切的紧迫性，以鼓励研究脂质的基本方面 液滴形成，生长，移动，成熟和降解以及脂质液滴如何影响细胞，组织和有机体 生理学并导致疾病。对这些概念的理解对于理由设计是必要的 适当的新治疗策略。 该会议将于2020年7月5日至8日在雪摩斯的雪人韦斯顿酒店举行。 格式包括托比亚斯·沃尔瑟（Tobias Walther）的开幕式主题演讲，邀请演讲者的六次会议， 以及从提交摘要中选出的学员和早期职业调查员的简短会谈，三个海报 会议，职业设计和平衡的职业研讨会以及有关高级专家会议 成像显微镜。会议格式将鼓励和促进学员之间的互动 职业调查人员和成熟的调查员。科学会议涵盖了脂质滴滴的全部宽度 从生物物理，生化和细胞主题到生理学和疾病的生物学。国际上的会谈 著名的研究人员将跨越临床研究并描述潜水员方法（生物物理学， 遗传学，生物化学，细胞生物学，生理学）和模型（小鼠，人类，培养细胞，苍蝇，酵母）。这 会议继续代表专门针对脂质液滴的主要国际会议， 仍然是一个独特的论坛，供研究人员交流思想并分享这种动态和分享成果 及时的字段。 这次会议的主要目的是培训和鼓励下一代科学家。 申请要求资金支持14名研究生，博士后研究员和早期的参与 职业调查人员，包括妇女，代表性不足的少数群体以及残疾人，他们将成为 从被认为是优越的提交摘要中选择。亲密的会议格式，分开的会议 网站，以及计划和计划外的参与者之间非正式互动的许多机会，将 为年轻的调查人员提供介绍其工作的机会，以获取该领域领导人的反馈， 并获得职业建议。