3D Shape Correspondence Quantification of Surgical Outcomes

手术结果的 3D 形状对应量化

基本信息

批准号：
7694353
负责人：
Lucia H Cevidanes
金额：
$ 11.1万
依托单位：
UNIV OF NORTH CAROLINA CHAPEL HILL
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
起止时间：
2008-09-30 至 2011-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7694353
关键词：
Address Arts Bone remodeling Classification Complex Computer Simulation Computer software Congenital Abnormality Data Data Set Deformity Dental Development Diagnosis Excision Future Gold Grant Growth Head Image Image Analysis Jaw Lateral Lead Left Location Maps Measurement Measures Medical Imaging Medical Research Methodology Methods Modeling Movement National Institute of Dental and Craniofacial Research Observational Study Operative Surgical Procedures Osteoarthrosis Deformans Outcome Outcome Assessment Physiological Adaptation Population Procedures Process Qualifying Quantitative Evaluations Randomized Clinical Trials Reliance Research Sampling Scanning Shapes Simulate Solid Splint Device Structure Surface Surgeon System Temporomandibular Joint Disorders Three-Dimensional Image Treatment/Psychosocial Effects United States National Institutes of Health Validation Work X-Ray Computed Tomography analytical tool clinical application cone-beam computed tomography craniofacial craniofacial complex design empowered improved innovation multidisciplinary novel orthognathic public health relevance simulation skeletal skull base tool treatment planning

项目摘要

DESCRIPTION (provided by applicant): Craniofacial deformities are among the most common of all birth defects, with 1- 2% of the US population having a deformity severe enough to be disabling or stigmatizing. Surgical procedures continue to be developed to reduce the serious functional and psychosocial effects of these conditions. But most procedures have not been assessed in a systematic way, and for a variety of reasons, many could never be assessed in a randomized clinical trial. Observational studies of the physiologic adaptations post-surgery have indicated that longitudinal assessments are as important. However, the surgeon's ability to assess complex corrective craniofacial procedures has been hampered by the lack of computational and analytical tools for 3D quantitative evaluation of longitudinal data. An image analysis system to register longitudinal Cone-Beam CT scans using the surface of the cranial base is a first step in the process of making 3D scans clinically useful. In this proposal, we are validating and applying a new model to quantify craniofacial deformity surgical outcomes. Using state of the art image analysis methods, regional skeletal changes due to surgical correction and post-surgical remodeling will be quantified. Our multidisciplinary team is well qualified to address these aims. This work will provide preliminary data for future research applications on 3D computer simulation for diagnosis and surgical treatment planning, and for outcome assessments of new treatment procedures. Public Health Relevance: Craniofacial deformities are among the most common of all birth defects, with 1- 2% of the US population having a deformity severe enough to be disabling or stigmatizing. Surgical procedures continue to be developed to reduce the serious functional and psychosocial effects of these conditions. However, the surgeon's ability to assess complex corrective craniofacial procedures has been hampered by the lack of computational and analytical tools for 3D quantitative evaluation of longitudinal data. In this proposal, we are validating and applying a new model to quantify craniofacial deformity surgical outcomes. This work will provide preliminary data for future research applications on 3D computer simulation for diagnosis and surgical treatment planning, and for outcome assessments of new treatment procedures.

描述（由申请人提供）：颅面畸形是所有出生缺陷中最常见的一种，1-2% 的美国人口患有严重到足以致残或耻辱的畸形。外科手术不断发展，以减少这些疾病对功能和社会心理的严重影响。但大多数程序尚未经过系统的评估，并且由于多种原因，许多程序永远无法在随机临床试验中进行评估。对术后生理适应的观察研究表明，纵向评估同样重要。然而，由于缺乏用于纵向数据 3D 定量评估的计算和分析工具，外科医生评估复杂颅面矫正手术的能力受到限制。使用颅底表面配准纵向锥形束 CT 扫描的图像分析系统是使 3D 扫描在临床上有用的过程的第一步。在这项提案中，我们正在验证并应用一种新模型来量化颅面畸形手术结果。使用最先进的图像分析方法，将量化由于手术矫正和术后重塑而引起的区域骨骼变化。我们的多学科团队完全有能力实现这些目标。这项工作将为诊断和手术治疗计划的 3D 计算机模拟的未来研究应用以及新治疗程序的结果评估提供初步数据。公共健康相关性：颅面畸形是所有出生缺陷中最常见的一种，1-2% 的美国人口患有严重到致残或耻辱的畸形。外科手术不断发展，以减少这些疾病对功能和社会心理的严重影响。然而，由于缺乏用于纵向数据 3D 定量评估的计算和分析工具，外科医生评估复杂颅面矫正手术的能力受到限制。在这项提案中，我们正在验证并应用一种新模型来量化颅面畸形手术结果。这项工作将为诊断和手术治疗计划的 3D 计算机模拟的未来研究应用以及新治疗程序的结果评估提供初步数据。

项目成果

期刊论文数量（4）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

A web-based system for statistical shape analysis in temporomandibular joint osteoarthritis.

基于网络的颞下颌关节骨关节炎统计形状分析系统。

DOI：
发表时间：
2019-02
期刊：
影响因子：
0
作者：
Michoud, Loic;Huang, Chao;Yatabe, Marilia;Ruellas, Antonio;Ioshida, Marcos;Paniagua, Beatriz;Styner, Martin;Gonçalves, João Roberto;Bianchi, Jonas;Cevidanes, Lucia;Prieto, Juan
通讯作者：
Prieto, Juan

Evaluation of tip and torque on virtual study models: a validation study.

虚拟研究模型上的尖端和扭矩评估：验证研究。

DOI：
发表时间：
2013-07-26
期刊：
影响因子：
0
作者：
Huanca Ghislanzoni, Luis T;Lineberger, Megan;Cevidanes, Lucia H S;Mapelli, Andra;Sforza, Chiarella;McNamara Jr, James A
通讯作者：
McNamara Jr, James A

Shape variation analyzer: a classifier for temporomandibular joint damaged by osteoarthritis.

形状变异分析仪：骨关节炎损伤的颞下颌关节分类器。

DOI：
发表时间：
2019-02
期刊：
影响因子：
0
作者：
Ribera, Nina Tubau;de Dumast, Priscille;Yatabe, Marilia;Ruellas, Antonio;Ioshida, Marcos;Paniagua, Beatriz;Styner, Martin;Gonçalves, João Roberto;Bianchi, Jonas;Cevidanes, Lucia;Prieto, Juan
通讯作者：
Prieto, Juan

3D PETCT Tumor Lesion Segmentation via GCN Refinement

通过 GCN 细化进行 3D PETCT 肿瘤病灶分割