Socio-Cultural Stress Profiles, Stress Responses, and Health in Mexican American Adolescents

墨西哥裔美国青少年的社会文化压力概况、压力反应和健康

• 批准号: 10023192
• 负责人: SU YEONG KIM
• 金额: $ 20.14万
• 依托单位: UNIVERSITY OF TEXAS AT AUSTIN
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-23 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10023192
• 关键词: Academic achievement; Acute; Adolescence; Adolescent; Adult; Affect; Alcohol or Other Drugs use; Attention; Award; Behavior; Behavioral; Blood Pressure; C-reactive protein; Child; Chronic; Complex; Data; Data Collection; Development; Diabetes Mellitus; Discrimination; Economically Deprived Population; Economics; Educational Status; Family; Foreigner; Future; Glycosylated hemoglobin A; Goals; Grant; Health; Hispanics; Hydrocortisone; Immigrant; Incidence; Individual; Inflammation; Interleukin-6; Language; Latino; Legal Status; Life; Limited English Proficiency; Link; Low income; Measures; Mediating; Medical; Mental Depression; Mexican; Mexican Americans; Mission; Modeling; Obesity; Outcome; Parents; Participant; Pathway interactions; Patient Self-Report; Phase; Physiological; Plague; Population; Poverty; Preventive Intervention; Process; Public Health; Recovery; Research; Research Personnel; Resources; Risk; Risk Factors; Sampling; Skin; Sleep; Social Environment; Source; Strategic Planning; Stress; Testing; Time; Translating; Trier Social Stress Test; United States National Institutes of Health; Variant; Wrist; adolescent health; adolescent health outcomes; biological adaptation to stress; cardiometabolic risk; cardiovascular disorder risk; cohort; diabetes risk; experience; health disparity; high risk; high school; improved; junior high school; low socioeconomic status; peer; physical conditioning; prospective; psychosocial; resilience; response; social; social culture; social stressor; stressor; success; virtual

This project is in response to PA-17-042 and examines the longitudinal influence of socio-cultural stressors, physiological and behavioral stress responses to these stressors, and health outcomes of adolescents in Mexican immigrant families. Recognizing the challenging social environments in which adolescents in Mexican immigrant families are embedded, this project creates socio-cultural stress profiles comprised of economic stress, discrimination and foreigner stress, and language brokering experiences (in which children translate between English and Spanish for their English-limited parents). Our ongoing research with adolescents in Mexican immigrant families has identified three socio-cultural stress profiles (moderate, protective, risk), three stable profiles over time (stable moderate, stable protective, stable risk), and two socio-cultural change profiles over time (improved, declined). The proposed project builds on a successful study of adolescents in Mexican immigrant families (PI: Kim, NSF, BCS-0956123 and BCS-651128; NIH, R03HD060045) to examine, prospectively, the influence of socio-cultural stress profiles in middle school alone, as well as continuity and change in socio-cultural stress profiles from middle school to high school, on adolescent health (Aim 1). Specifically, this grant will allow the research team to add measures of physiological health outcomes, namely inflammation (IL-6, C-reactive protein) and diabetes risk (hemoglobin A1c). We will also test a pathways model, to determine whether socio-cultural stress profiles are associated with adaptive or maladaptive physiological and behavioral stress responses that influence health (Aim 2). Further, we propose to test whether the associations from socio-cultural stress profiles to stress responses to health outcomes are exacerbated or mitigated through various moderators, including personal (resilience, parent support) and cultural (family obligation) resources, stress related to legal status, and language brokering places and content (Aim 3). Physiological stress response will be assessed via cortisol. Acute cortisol will be assessed by measuring reactivity and recovery to an adaptation of the Trier Social Stress Test, in which adolescents verbally translate a medical document for their parents. Day-to-day cortisol will also be measured. Substance use and sleep are self-reported daily, and motionlogger watches worn on the wrist provide an objective assessment of sleep. This study is very much in line with the 2016-2020 NIH strategic plan of studying normative populations to detect points for preventive interventions to reduce health disparities. It does so by studying socio-cultural stress profiles that include language brokering experiences, a common phenomenon in low-income Mexican immigrant families that has received little attention to date. We examine the complex conditions under which socio-cultural profiles can function as sources of both risk and protection for adolescents. This project has the potential to uncover processes and practices that can reduce persistent health disparities in Mexican immigrant families.

该项目是对PA-17-042的回应，研究了社会文化压力源的纵向影响， 对这些压力源的生理和行为压力反应，以及青少年的健康结果 墨西哥移民家庭。认识到墨西哥青少年的具有挑战性的社会环境 移民家庭被嵌入，该项目创建了由经济组成的社会文化压力概况 压力，歧视和外国人的压力以及语言经纪经验（儿童翻译 在英语和西班牙语之间以其英语限制的父母）。我们正在与青少年进行的研究 墨西哥移民家庭已经确定了三个社会文化压力概况（中度，保护性，风险），三个 随着时间的推移稳定的概况（稳定，稳定的保护性，稳定的风险）和两个社会文化变革概况 随着时间的流逝（改进，拒绝）。拟议的项目以对墨西哥青少年的成功研究为基础 移民家庭（PI：Kim，NSF，BCS-0956123和BCS-651128； NIH，R03HD060045） 前瞻性地，仅中学以及连续性和连续性和 关于青少年健康的社会文化压力概况的变化（AIM 1）。 具体而言，该赠款将使研究团队能够添加生理健康成果的度量，即 炎症（IL-6，C反应蛋白）和糖尿病风险（血红蛋白A1C）。我们还将测试一个途径模型， 确定社会文化压力特征是否与适应性或不良适应性生理有关 以及影响健康的行为压力反应（目标2）。此外，我们建议测试是否 从社会文化压力概况到对健康结果的压力反应的关联会加剧或 通过各种主持人（包括个人（弹性，父母支持）和文化（家庭）来缓解 义务）资源，与法律地位有关的压力以及语言经纪地点和内容（AIM 3）。 生理压力反应将通过皮质醇评估。急性皮质醇将通过测量评估 反应性和恢复对Trier社会压力测试的适应 父母的医疗文件。还将测量日常皮质醇。药物使用和睡眠是 每天自我报告，手腕上戴在手腕上的手表提供了对睡眠的客观评估。这 研究非常符合2016 - 2020年NIH研究规范人群的战略计划 预防干预措施减少健康差异的要点。它通过研究社会文化压力来做到这一点 包括语言经验体验的概况，这是低收入墨西哥的常见现象 迄今为止很少关注的移民家庭。我们检查了复杂条件 社会文化概况可以充当青少年风险和保护的来源。这个项目有 揭示可能减少墨西哥移民持续健康差异的过程和实践的潜力 家庭。