Core Grant for Vision Research

视觉研究核心资助

基本信息

批准号：
7633128
负责人：
CHRISTOPHER W TYLER
金额：
$ 72.57万
依托单位：
SMITH-KETTLEWELL EYE RESEARCH INSTITUTE
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
起止时间：
1997-07-01 至 2011-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7633128
关键词：
Aging Area Binocular Vision Biophysics Brain imaging Cancer Center Support Grant Clinical Collaborations Communication Communities Computers Development Disabled Persons Electronics Engineering Equipment Design Experimental Psychology Explosion Eye Functional Magnetic Resonance Imaging Funding Grant Head Image Imaging Techniques Individual Laboratory Animals Magnetic Resonance Imaging Maintenance Medical Ophthalmology Optometry Photoreceptors Postdoctoral Fellow Preparation Primates Principal Investigator Process Productivity Research Research Institute Resource Sharing Resources Scientist Services Technical Expertise Techniques Technology Training Vision Vision Disorders Vision research Visual Pathways Visual system structure Work animal resource experience interest neurophysiology object recognition oculomotor optical imaging

项目摘要

DESCRIPTION (provided by applicant): Research at the Smith-Kettlewell Eye Research Institute (SKERI) is focused on clinical and basic studies in vision and disorders of the visual system. Smith-Kettlewell scientists have training from diverse medical and scientific backgrounds: ophthalmology, neurophysiology, experimental psychology, engineering, optometry and biophysics. Their main topics of study are oculomotor processing, dynamics of binocular vision, cortical organization and development of the visual pathways, vision in the aging eye, analysis of photoreceptor function, object recognition and computational vision in the service of the disabled. Particular emphasis has been laid on the application of modern imaging techniques to these problems, including the diverse techniques of multifocal ERG, MRI, fMRI, DTI, whole-head VEP, whole-head MEG, optical imaging of cortex, and SLO imaging. For the past three decades, the NEI Core Grant has formed the central component of its most important shared research services, chiefly computer communication and resources, and electronic equipment design and maintenance. Given the moderate scale of the Smith-Kettlewell group, the proximity of the scientists, and their common research interests, collaboration among scientists is standard practice. Principal Investigators share resources with little difficulty. The technical expertise of our Computer Services and Electronics Hardware modules greatly benefits the rapid development of new research agendas - a tremendous advantage for new principal investigators and postdoctoral fellows, and a major factor in our high productivity. In recent years, the vision community has experienced an explosion of research in the area of brain imaging. Smith-Kettlewell has kept step with this technology and has several grants currently funded, with many other projects in the works. The addition of a Brain Imaging Module will provide valuable support resources in the areas of MRI, fMRI, whole-head VEP, DTI, and whole-head MEG imaging that are impractical to provide on individual grants. In addition, a Laboratory Animal Resources Module will provide the technical support and resources necessary to continue the high-level research conducted on the alert behaving primate preparation conducted by a number of groups at Smith-Kettlewell.

描述（由申请人提供）：史密斯-凯特尔韦尔眼科研究所 (SKERI) 的研究重点是视力和视觉系统疾病的临床和基础研究。 Smith-Kettlewell 的科学家接受过不同医学和科学背景的培训：眼科、神经生理学、实验心理学、工程学、验光和生物物理学。他们的主要研究课题是动眼神经处理、双眼视觉动力学、皮层组织和视觉通路的发育、老化眼睛的视觉、光感受器功能分析、物体识别和为残疾人服务的计算视觉。特别强调现代成像技术在这些问题上的应用，包括多焦ERG、MRI、fMRI、DTI、全头VEP、全头MEG、皮层光学成像和SLO成像等多种技术。在过去的三十年中，NEI 核心拨款已成为其最重要的共享研究服务的核心组成部分，主要是计算机通信和资源以及电子设备设计和维护。鉴于史密斯-凯特韦尔小组的规模适中、科学家之间的距离较近以及他们共同的研究兴趣，科学家之间的合作是标准做法。首席研究员可以轻松共享资源。我们的计算机服务和电子硬件模块的技术专长极大地有利于新研究议程的快速发展——这对于新的首席研究员和博士后研究员来说是一个巨大的优势，也是我们高生产力的一个主要因素。近年来，视觉界经历了脑成像领域研究的爆炸式增长。 Smith-Kettlewell 一直在研究这项技术，目前已获得多项资助，还有许多其他项目正在进行中。脑成像模块的增加将为 MRI、fMRI、全头 VEP、DTI 和全头 MEG 成像领域提供宝贵的支持资源，而这些资源无法通过个人资助提供。此外，实验动物资源模块将提供必要的技术支持和资源，以继续由史密斯-凯特韦尔的多个小组对灵长类动物的警觉行为准备进行高水平研究。