Affordable wireless recording for mice

经济实惠的鼠标无线录音

• 批准号: 10013290
• 负责人: Mee H Choi
• 金额: $ 74.95万
• 依托单位: JINGA-HI, INC.
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-08-01 至 2022-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10013290
• 关键词: Adopted; Adoption; Amplifiers; Animal Model; Animals; Back; Behavior; Behavioral; Biological Models; Coin; Communities; Computer software; Development; Devices; Documentation; Electric Stimulation; Electroencephalography; Electrophysiology (science); Engineering; Environment; Equipment; Event; Feedback; Future; Genetic Models; Goals; Grant; Head; Health; Hour; Industry; Instruction; Letters; Marketing; Microfabrication; Mus; Neurosciences; Neurosciences Research; Performance; Phase; Play; Rattus; Research Personnel; Safety; Signal Transduction; Source Code; System; Techniques; Technology; Time; Wireless Technology; Work; analog; base; cost; digital; experience; experimental study; flexibility; in vivo; light weight; member; microstimulation; open source; prototype; relating to nervous system; software development; transmission process; wireless communication

Project Summary Mice offer a powerful genetic model system, thus are the single most used animal model in neuroscience. Despite potential benefits of wireless recording (more flexible, safer, and more natural in vivo neural recording), adoption of wireless recording in the neuroscience community for mice for a wider neuroscience community had been slow, due to the engineering complexity to enable a lightweight device record/transmit high fidelity/multichannel/high bandwidth signals for reasonable recording hours. Wireless neuro recording devices on the market are currently either analog based transmission, trade low count/low channel for longer hours, too heavy for mice or still too expensive. None provide simultaneous recording and electrical stimulation for high channels with full integration into behavioral software ideal for mice yet. Jinga-hi, Inc.'s JAGA Penny (as a final product) will be unique on the market as a compact (coin-sized all in one), affordable ($5.5-7.5K), high quality, multichannel wireless system capable of simultaneous neural recording (up to 32 ch) and stimulation (up to 16/32 ch) for high band signals (unit recording) as well as low band signals for mice. In addition, our easy to use and scalable (4-8 devices at the same time) system will be fully integrated into available leading behavioral and video/event-tracking software on the market. We anticipate that JAGA Penny will widely assist neuroscientists' efforts in combining electrophysiology and behavior experiments in a more natural in vivo environment.

项目摘要 小鼠提供了强大的遗传模型系统，因此是神经科学中最常用的动物模型。尽管 无线记录的潜在好处（更灵活，更安全，更自然的体内神经记录），采用 由于神经科学社区的无线录制，用于更广泛的神经科学界的小鼠，由于 工程复杂性以启用轻质设备记录/传输高保真/多通道/高带宽信号 在合理的记录时间内。市场上的无线神经记录设备目前是基于模拟的 传输，交易低计数/低通道持续更长的时间，对于小鼠来说太重或仍然太昂贵。没有提供 同时记录和对高通道的电刺激，并完全集成到行为软件中 老鼠。 Jinga-hi，Inc。的Jaga Penny（作为最终产品）将在市场上以紧凑型（硬币大小）为独特， 负担得起（$ 5.5-7.5k），高质量，多通道无线系统，可同时进行神经记录（最多32 ch） 对于高带信号（单位记录）以及小鼠的低带信号的刺激（最多16/32 CH）。此外， 我们易于使用和可扩展的（同时4-8个设备）系统将完全集成到可用的领导中 市场上的行为和视频/事件跟踪软件。我们预计Jaga Penny将广泛协助 神经科学家在更自然的体内环境中结合电生理学和行为实验的努力。