University of Washington LURN II Research Site

华盛顿大学 LURN II 研究基地

基本信息

批准号：
10011799
负责人：
Claire C Yang
金额：
$ 42.4万
依托单位：
UNIVERSITY OF WASHINGTON
依托单位国家：
美国
项目类别：
财政年份：
2013
资助国家：
美国
起止时间：
2013-07-15 至 2024-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10011799
关键词：
Adopted Biological Biological Markers Bladder Caring Characteristics Clinical Clinical Data Clinical Management Clinical Trials Cohort Studies Complex Data Data Analyses Data Coordinating Center Development Diabetes Mellitus Digestive System Disorders Efferent Neurons Elements Ensure Functional disorder Funding Goals Guidelines Health Technology Incontinence Individual Infrastructure Institutes Joints Kidney Diseases Knowledge Link Lower urinary tract Measurement Measures Modeling Motor Muscle Organ Outcome Outcome Measure Participant Patient Care Patient Monitoring Patient Outcomes Assessments Patient Self-Report Patients Persons Physiological Plasma Productivity Proteins Protocols documentation Request for Applications Research Research Personnel Resources Sampling Self Assessment Sensory Severities Site Subgroup Symptoms Testing Time Translating Treatment outcome Universities Urethra Urinary tract Washington Woman Work afferent nerve base clinical care clinically relevant cohort experience improved instrument lower urinary tract symptoms mHealth member men micturition urgency novel patient oriented patient population patient subsets recruit response success symptom cluster tool urinary

项目摘要

Project summary This proposal responds to RFA-DK-18-510, which requests applications for Research Sites to continue in the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN). In this application, the University of Washington (UW) seeks support for a Research Site to participate in efforts to unravel the clinically confounding symptoms of the lower urinary tract. This proposal was developed following the guidelines stipulated by the National Institute of Diabetes, Digestive and Kidney diseases (NIDDK). The aim of the proposed UW Research Site, in conjunction with the Data Coordination Center and LURN Research Sites, is to develop and validate symptom-based instruments to measure lower urinary tract symptoms both in men and women, and to better define the subtypes of persons with lower urinary tract symptoms. The key responsibilities of the Research Site will be to adopt the study protocols developed by the LURN investigators, validate the developed Patient Reported Outcome (PRO) measures, recruit study participants, and conduct extensive characterization (subtyping) of them.

项目概要该提案是对 RFA-DK-18-510 的回应，该提案要求继续在下尿路功能障碍研究网络 (LURN) 的症状。在本申请中，大学华盛顿大学 (UW) 寻求对研究中心的支持，以参与解开临床问题的努力下尿路的混杂症状。该提案是根据指导方针制定的由国家糖尿病、消化和肾脏疾病研究所 (NIDDK) 规定。该组织的目标是拟议的华盛顿大学研究站点与数据协调中心和 LURN 研究站点一起，旨在开发和验证基于症状的仪器来测量男性和女性的下尿路症状女性，并更好地定义具有下尿路症状的人的亚型。关键研究中心的职责是采用 LURN 研究人员制定的研究方案，验证制定的患者报告结果 (PRO) 措施、招募研究参与者并进行对它们进行广泛的表征（子类型化）。