BASE CONTRACT: YEAR 1 - PRECLINICAL MEDICATIONS SCREENING IN ALCOHOL PREFERRING RATS. BASE PERIOD (FY-19). PERIOD OF PERFORMANCE: 09/29/19 - 09/28/20.

基础合同：第一年 - 在酒精偏好大鼠中进行临床前药物筛选。

• 批准号: 10037799
• 负责人: RICHARD L. BELL, PH.D.
• 金额: $ 38.22万
• 依托单位: TRUSTEES OF INDIANA UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-29 至 2020-09-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10037799
• 关键词: Alcohol consumption; Alcohols; Contracts; Development; Intellectual Property; Performance; Pharmaceutical Preparations; Rattus; Testing; alcohol preferring rats; base; blind; design; drug testing; efficacy testing; interest; preclinical efficacy; screening

This contract is for the blind efficacy testing of reference compounds and compounds of interest on voluntary alcohol drinking by alcohol preferring P and HAD1 rats and provide analysis of said testing. The contract has an intellectual property clause that is Bayh–Dole Act compliant, while offering protection that is attractive to proprietary compound suppliers. This facilitates our ability to test drugs that may eventually be developed commercially. The preclinical efficacy test are designed to inform decisions about further development.

该合同是用于对参考化合物的盲目效率测试和对饮酒的自愿饮酒的感兴趣的化合物偏爱P和1只大鼠，并提供了该测试的分析。该合同的知识产权条款符合Bayh -Dole Act，同时提供了吸引专有复合供应商的保护。该设施是我们测试最终可以在商业上开发的药物的能力。临床前效率测试旨在为有关进一步发展的决策提供信息。