2/2 Southeast Partnership for Improving Research & Training in Cancer Health Disparities

2/2 东南部改善研究伙伴关系

• 批准号: 10005326
• 负责人: Lucio Miele
• 金额: $ 4.76万
• 依托单位: LSU HEALTH SCIENCES CENTER
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-21 至 2022-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10005326
• 关键词: Advanced Malignant Neoplasm; Advisory Committees; Advocacy; African; Biological; Cancer Center; Collaborations; Communication; Communities; Community Networks; Education; Education and Outreach; Educational Curriculum; Effectiveness; Ensure; European; Evaluation; Feedback; Fostering; Genetic; Goals; Grant; Guidelines; Health Sciences; Institution; Joints; Latina; Leadership; Link; Logistics; Louisiana; Malignant Neoplasms; Medical Students; Monitor; Native Americans; Patients; Personnel Management; Persons; Preparation; Publications; Records; Reporting; Research; Research Personnel; Research Project Grants; Research Training; Schedule; Scientist; Series; Students; Teleconferences; Training; Translational Research; Underrepresented Students; Underserved Population; United States National Institutes of Health; Universities; Update; anticancer research; base; biobank; breast cancer genomics; cancer health disparity; education research; experience; health disparity; health equity; high standard; improved; inter-institutional; malignant breast neoplasm; meetings; member; minority communities; multidisciplinary; outreach; precision medicine; programs; racial and ethnic; summer research; undergraduate student

ABSTRACT – Administrative Core The Southeast Partnership for Improving Research and Training in Cancer Health Disparities (SPIRIT-CHD) unites the Louisiana State University Health Sciences Center (LSUHSC), an institution serving underserved populations and underrepresented students (ISUPS), and the NCI-designated Moffitt Cancer Center (MCC) to advance translational research on the biological mechanisms of cancer health disparities focusing on biospecimen-based research and precision medicine education. The Administrative Core (AC) provides the necessary central oversight, coordination, support and logistics needed to make SPIRIT-CHD function effectively, with ongoing communications and improvements being key responsibilities. To achieve this, the AC has the following objectives: a) oversee planning activities; b) coordinate and monitor the pilot research projects and the cancer research education program; c) foster productive interactions among collaborators, Early Stage Investigators (ESIs), and students; d) monitor progress and conduct evaluations of component sections, e) review and revise short-term and long-range plans on a regular basis; f) ensure the highest standards of scientific integrity for all project and program components and activities, and g) stimulate new research collaborations related to health disparities; and h) ensure integration among the programs and cores. The AC is led by a multidisciplinary team of established investigators, is guided by an Internal Advisory Committee that is comprised of community-academic members, and is highly supported by leadership of both institutions. It synergistically links and builds on our experiences with other PACHE, CURE, and Community Network Partnership Programs. A series of planning and priority-setting steps will be implemented to establish regular and ongoing interactions, in-person retreats, and other communication channels to facilitate: 1) conduct of a pilot research program beginning with a project centered on breast cancer genomics utilizing breast cancer biospecimens from Latina patients of mixed genetic ancestry (African, Native American, European); and 2) implementation of a three-pronged joint Cancer Research Education Program that provides undergraduate and medical students with a hands on summer research experience, delivers a curriculum and focused training to the students on biobanking, precision medicine and cancer health disparities and expands existing outreach education to our respective racial/ethnic minorities communities. Importantly, the AC ensures that guidance and feedback are provided as necessary to achieve partnership goals and integration of SPIRIT-CHD components. Overall, the AC facilitates the coordination and communication necessary for a seamless and mutually beneficial inter-institutional partnership to advance the feasibility, planning and implementation of focused collaborations in cancer-related research, cancer research experience and outreach education.

摘要 – 行政核心 改善癌症健康差异研究和培训的东南伙伴关系 (SPIRIT-CHD) 联合了路易斯安那州立大学健康科学中心 (LSUHSC)，这是一个服务于服务不足的机构 人群和代表性不足的学生 (ISUPS) 以及 NCI 指定的莫菲特癌症中心 (MCC) 癌症健康差异的生物学进展机制的转化研究重点关注 基于生物样本的研究和精准医学教育。 使 SPIRIT-CHD 发挥作用所需的必要中央监督、协调、支持和后勤 为实现这一目标，审计委员会的主要职责是持续沟通和改进。 具有以下目标： a) 监督规划活动； b) 协调和监督试点研究 项目和癌症研究教育计划；c) 促进合作者之间富有成效的互动， 早期研究人员 (ESI) 和学生；d) 监控进展并进行组件评估 e) 定期审查和修订短期和长期计划 f) 确保最高水平； 所有项目和计划组成部分及活动的科学完整性标准，以及 g) 激发新的 与健康差异相关的研究合作；和 h) 确保计划和核心之间的整合。 审计委员会由一个由资深调查员组成的多学科团队领导，并接受内部顾问的指导 委员会由社区学术成员组成，并得到双方领导层的大力支持 它协同联系并建立在我们与其他 PACHE、CURE 和社区的经验之上。 将实施一系列规划和优先事项设定步骤来建立网络伙伴关系计划。 定期和持续的互动、面对面的静修和其他沟通渠道，以促进：1) 进行 试点研究计划以利用乳腺癌的乳腺癌基因组学为中心的项目开始 来自基因混合血统的拉丁裔患者（非洲人、美洲原住民、欧洲人）的生物样本；2) 实施三管齐下的联合癌症研究教育计划，为本科生和 拥有暑期研究实践经验的医学生，提供课程和重点培训 学生们了解生物样本库、精准医学和癌症健康差异并扩大现有范围 重要的是，AC 确保提供指导。 并根据需要提供反馈，以实现合作伙伴目标和 SPIRIT-CHD 整合 总体而言，AC 促进了无缝和必要的协调和沟通。 互利的机构间伙伴关系，以推进可行性、规划和实施 重点在癌症相关研究、癌症研究经验和推广教育方面进行合作。