Developmental Research Projects

发展研究项目

• 批准号: 10005931
• 负责人: Nathan A. Berger
• 金额: $ 6.68万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-18 至 2022-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10005931
• 关键词: Affect; Award; Biological; Biomedical Engineering; Breast; Cancer Center; Clinical; Collaborations; Colorectal; Communication; Communities; Comprehensive Cancer Center; Core Facility; Data; Development; Diagnosis; Discipline; Early Diagnosis; Epidemiology; Ethnic group; Etiology; Evaluation; Faculty; Financial Support; Funding; Future; Genetic; Goals; Grant; Head; Hospitals; Individual; Informatics; Institution; Leadership; Lung; Malignant Neoplasms; Malignant neoplasm of gastrointestinal tract; Molecular; Monitor; Outcome; Peer Review Organizations; Performance; Pilot Projects; Population; Prevention; Productivity; Program Evaluation; Program Research Project Grants; Prostate; Reporting; Reproduction spores; Research; Research Activity; Research Methodology; Research Personnel; Research Project Grants; Scientist; Series; Services; Sociology; Study Section; System; Translational Research; United States National Institutes of Health; University Hospitals; anticancer research; base; burden of illness; cancer health disparity; cancer research center director; community based participatory research; comparative effectiveness; experience; high risk; innovation; interest; meetings; member; mortality; novel; novel strategies; preference; programs; psychosocial; racial and ethnic; social; socioeconomic disadvantage; socioeconomics; translational scientist

CASE COMPREHENSIVE CANCER CENTER DISPARITIES SPORE DEVELOPMENTAL RESEARCH PROGRAM (DRP) SUMMARY/ABSTRACT The overall objective of the Case Comprehensive Cancer Center Disparity SPORE Developmental Research Program (DRP) is to develop innovative and diverse approaches to focus on disparities translational research across the spectrum from etiology, prevention, early detection, diagnosis, therapy, survival, disease burden, and mortality in cancers found to disparately affect disadvantaged socioeconomic and racial/ethnic groups. The Case Disparities SPORE DRP will provide 1) Financial support, 2) Core Facility Services, and 3) Intellectual Oversight and Advice for pilot research projects and investigators. Emphasis will be placed on supporting new investigators, as well as, established investigators with new approaches to Disparities Research. To stimulate translational research, pilot projects with 2 Co-PI's, one basic, one clinical and/or one community-based investigator, will be given preference. For meritorious proposals from individual basic, clinical or community- based investigators, the DRP leadership group will identify complementary translational investigators to serve as advisors. The Case Disparities SPORE considers the pilot project mechanism to be an important opportunity for initiation of high risk/high impact research and will accordingly provide appropriate prioritization for such proposals. With support from the collaborating institutions and $50,000 from the SPORE Grant Award, the Case Disparities SPORE will support four pilot projects per year at $50,000 each. Solicitation for pilot projects will be announced by multiple, institution wide, electronic notice systems, by direct communication with Case Comprehensive Cancer Center directors, department heads and deans of participating institutions and by invitations to specific scientists with exciting new approaches. Pilot proposals will be evaluated using the NIH 9 point scoring system by the DRP Evaluation Panel composed of selected series of faculty members representing all participating institutions, with expertise in basic, clinical, translational, epidemiological, sociological and community-based research, and with involvement and experience in NIH and other national organization peer review study sections. Ongoing intellectual and performance oversight, evaluation and advice regarding implementation, conduct and productivity of research will be monitored and guided by a regular series of reports, scientific presentations and meetings between investigators and leadership.

案例综合癌症中心差异孢子 发展研究计划（DRP） 摘要/摘要 案例综合癌症中心差异孢子发育研究的总体目标 计划（DRP）是开发创新和多样化的方法来专注于差距转化研究 在病因，预防，早期检测，诊断，治疗，生存，疾病负担和 发现癌症的死亡率不同，会对不利的社会经济和种族/种族群体产生不同的影响。这 病例差异孢子DRP将提供1）财政支持，2）核心设施服务，3）智力 对试点研究项目和研究人员的监督和建议。重点将放在支持新的地方 研究人员以及建立了具有新方法研究方法的研究人员。刺激 翻译研究，试点项目，带有2个Co-Pi，一个，一个基础，一个临床和/或一个基于社区的临床和/或 研究人员将获得偏爱。对于来自个人基础，临床或社区的有功建议 - DRP领导小组基于研究人员将确定互补的翻译调查员以服务 作为顾问。案例差异孢子认为试点项目机制是重要的机会 为了启动高风险/高影响力研究，因此将为此类提供适当的优先级 建议。在合作机构的支持下，从孢子赠款奖中获得50,000美元的支持，此案 差异孢子将每年以每年50,000美元的价格支持四个试点项目。试点项目的征集将是 由多个机构范围的电子通知系统宣布，直接与案件沟通 参与机构的综合癌症中心董事，部门负责人和院长 以令人兴奋的新方法向特定科学家的邀请。试点建议将使用NIH 9进行评估 DRP评估面板的点评分系统由选定的一系列教职员工组成 所有参与机构，具有基本，临床，转化，流行病学，社会学和社会学和 基于社区的研究，并在NIH和其他国家组织的同伴中参与和经验 审查研究部分。关于智力和绩效监督，评估和建议 研究的实施，行为和生产力将受到一系列常规报告的监视和指导， 调查人员与领导力之间的科学演讲和会议。