Canvass: revitalizing and advancing the translation of natural products research

游说：振兴和推进天然产物研究的转化

• 批准号: 10001307
• 负责人: Matthew Hall
• 金额: $ 4.76万
• 依托单位: NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10001307
• 关键词: Biodiversity; Biological; Biological Assay; Biology; Data Set; Goals; Human; Informatics; Medicine; Natural Products; Organism; Pharmaceutical Preparations; Publications; Research; Research Project Grants; Source; Therapeutic; Translations; Work; design; human disease; novel; screening; screening program; small molecule

Canvass provides an opportunity to screen natural products in a large set of biological assays designed to encompass a diversity of biology to uncover novel activities and modes of action for these valuable molecules. During this period, NCGC completed the full review of the screening campaign including a diversity of informatics analyses and submitted a publication on the overall screening program. The complete dataset was also made available to the public. In addition, promising biological findings from the screen are being fully evaluated and may result in new research projects as potential therapeutic hypotheses.

画布提供了一个机会，可以在一系列生物学测定中筛选天然产品，旨在涵盖各种生物学，以发现这些有价值的分子的新型活动和作用方式。 在此期间，NCGC完成了对筛选活动的完整审查，包括各种信息学分析，并提交了整体筛选计划的出版物。完整的数据集也向公众提供。此外，屏幕上有希望的生物学发现正在得到充分评估，并可能导致新的研究项目作为潜在的治疗假设。