RESTORATION OF HEPATIC FUNCTION IN LIVING LIVER DONORS (ANCILLARY STUDY OF A2ALL

活体肝捐献者肝功能的恢复（A2ALL 的辅助研究

• 批准号: 7604422
• 负责人: Gregory Thomas Everson
• 金额: $ 0.4万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-07-01 至 2008-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7604422
• 关键词: Ancillary Study; Blood Tests; Computer Retrieval of Information on Scientific Projects Database; Excision; Funding; Grant; Hepatic; Image; Institution; Laboratories; Life; Liver; Lobe; Measures; Patients; Purpose; Rate; Research; Research Personnel; Resources; Source; Standards of Weights and Measures; Testing; Tissues; Transplantation; United States National Institutes of Health; liver function; restoration; size

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to determine the rate and extent of return of full liver function in patients who undergo removal of the right lobe of their liver for donation for transplantation. Standard blood tests and x-ray imaging of your liver do not give complete information about the degree of liver function. In this study we will use special tests to measure your liver's function and size, as well as the amount of regrowth of liver tissue that occurs after the right lobe is removed. These tests may be better than standard laboratory tests in measuring the degree of return of function after right lobe donation. These tests may also be useful in predicting which patients may suffer complications, especially those related to delay in return of liver function.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 本研究的目的是确定接受肝右叶切除捐献移植的患者完全肝功能恢复的速度和程度。 标准血液检查和肝脏 X 射线成像并不能提供有关肝功能程度的完整信息。 在这项研究中，我们将使用特殊测试来测量肝脏的功能和大小，以及右叶切除后肝组织的再生量。 这些测试在测量右叶捐赠后功能恢复程度方面可能比标准实验室测试更好。 这些测试也可能有助于预测哪些患者可能会出现并发症，尤其是与肝功能恢复延迟相关的并发症。