The Administrative Core will support Udall Center activities at the University of Rochester

行政核心将支持罗切斯特大学尤德尔中心的活动

基本信息

批准号：
10017334
负责人：
Earl Ray Dorsey
金额：
$ 24.44万
依托单位：
UNIVERSITY OF ROCHESTER
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-09-30 至 2023-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10017334
关键词：
Advocacy Big Data Caring Cellular Phone Clinical Markers Clinical Research Clinical Sciences Clinical Trials Clinical and Translational Science Awards Communities Computational Science Computers Country Data Science Data Scientist Development Disease Progression Disease model Electrical Engineering Enrollment FDA approved Fellowship Fellowship Program Funding Generations Genetic Markers Grant Health Health Technology Individual Infrastructure Institutes Institution Interdisciplinary Study Investigational Therapies Leadership Mission Movement Disorders Neurology Participant Pharmacologic Substance Positioning Attribute Randomized Controlled Trials Recording of previous events Research Research Personnel Resources Role Scientist Technology Telemedicine Therapeutic Training Training Programs Translational Research United States National Institutes of Health Universities University resources advanced analytics advocacy organizations career development clinical center health professional shortage areas human capital innovation multidisciplinary novel novel strategies outreach research and development research study tool virtual wearable sensor technology

项目摘要

SUMMARY The UR-Udall Center's Administrative Core will utilize the established resources of the University of Rochester's Center for Health + Technology (CHeT). Over the past 25 years, CHeT has pioneered multi-center research studies that have enrolled 40,000 individuals in 120 studies that have led to seven FDA-approved therapies, including four for PD. More recently, CHeT has used technology to transform PD research and care. Among these PD initiatives are disease models that have identified novel clinical and genetic markers of disease progression, the first two virtual PD research studies, the two largest smartphone studies in PD, the first longitudinal wearable sensor study for PD, and the only national randomized controlled trial of telemedicine for PD. The University's Goergen Data Science Institute and the University of Rochester's Clinical and Translational Science Institute will support the Administrative Core. In addition, a multidisciplinary network of leading investigators from top institutions, including Johns Hopkins, Aston University, and MIT, and innovative collaborators, such as 23andMe and Sage Bionetworks, will guide and assist with executing the UR-Udall Center's activities. The Administrative Core will conduct unparalleled outreach at the state, national, and global level. CHeT will utilize its statewide telemedicine network, which cares for hundreds in health professional shortage areas, to bring research opportunities to individuals in their communities. Working with the nation's largest advocacy organizations, the Core will enable national participation in research. Using its recently launched ParkinsonTV, the UR-Udall Center will reach 100,000's of individuals globally to educate them about PD and novel research. Finally, the Core will leverage the Department of Neurology's T32 fellowship program in experimental therapeutics, as well as extensive research and career development opportunities, to assemble and cross-train clinician-scientists and 10-20 computer scientists, mathematicians, and electrical engineers in PD research to create the first collaborative group of PD investigators with both clinical research and computational science expertise. This influx and development of scarce human capital will be one of the UR-Udall Center's many enduring and valuable contributions to the field.

概括 Ur-udall中心的行政核心将利用大学的既定资源罗切斯特卫生 +技术中心（CHET）。在过去的25年中，Chet开创了多中心研究的研究已在120项研究中招募了40,000名个人，这些研究导致了7个FDA批准疗法，包括四种PD。最近，Chet使用技术来改变PD研究和护理。在这些PD计划中，疾病模型已经确定了新的临床和遗传标记疾病进展，前两项虚拟PD研究，PD的两项最大智能手机研究， PD的首次纵向可穿戴传感器研究，也是唯一的国家随机对照试验 PD的远程医疗。该大学的Goergen数据科学研究所和罗切斯特大学的临床和翻译科学研究所将支持行政核心。此外，一个多学科网络来自约翰·霍普金斯，阿斯顿大学和麻省理工学院在内的顶级机构的主要调查员以及创新的合作者，例如23andme和Sage Bionetworks，将指导和协助执行Ur-udall 中心的活动。行政核心将在州，国家和全球一级进行无与伦比的外展。切特将利用其全州远程医疗网络，该网络关心数百个卫生专业短缺地区，为社区中的个人带来研究机会。与国家最大的倡导合作组织，核心将使国家参与研究。使用最近推出的Parkinsontv， Ur-udall中心将在全球范围内达到100,000个个人，以教育他们有关PD和新颖研究的知识。最后，核心将利用神经病学部的T32奖学金计划治疗剂以及广泛的研究和职业发展机会，以组装和交叉培训 PD研究中的临床医生科学家和10-20位计算机科学家，数学家和电气工程师与临床研究和计算科学创建第一个合作小组的PD研究人员专业知识。稀缺人力资本的这种涌入和发展将是Ur-udall中心的众多对该领域的持久和宝贵的贡献。