Building a patient-centered cancer data mart in a rural state

在农村州建立以患者为中心的癌症数据集市

• 批准号: 10016265
• 负责人: BRADLEY D MCDOWELL
• 金额: $ 9.81万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-11 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10016265
• 关键词: Area; Big Data; Cancer Center; Cancer Patient; Clinical; Comprehensive Cancer Center; Data; Data Collection; Data Mart; Data Set; Diagnosis; Environmental Exposure; Epidemiology; Funding; Goals; Holden Comprehensive Cancer Center at the University of Iowa; Hospitals; Iowa; Leadership; Malignant Neoplasms; Methods; Molecular; Patients; Population; Population Research; Population Sciences; Prospective Studies; Request for Applications; Research; Research Design; Research Personnel; Resource Sharing; Resources; Retrospective Studies; Rural; Rural Population; Speed; Universities; Work; anticancer research; data curation; data registry; data resource; data sharing; data standards; experience; insurance claims; interdisciplinary collaboration; neoplasm registry; patient oriented; patient population; personalized cancer care; population based; social; tissue resource; tool

Abstract The University of Iowa Holden Comprehensive Cancer Center (HCCC) is an NCI-funded comprehensive cancer center with a strong culture of transdisciplinary collaboration. It is the only academic cancer center in the state of Iowa and serves a rural population with unique environmental exposures. The Population Research Core is a HCCC shared resource that provides centralized leadership for harnessing clinical and population-based tools and data resources, eliminating barriers to their use. Led by its Director, Dr. Bradley McDowell, the Core provides epidemiology expertise, study design, enhanced data sharing, and distributed prep-to-research queries that promote rigorous retrospective and prospective studies using robust data collection and data curation methods. Dr. McDowell's expertise in these areas is particularly important as we apply big data approaches that integrate social, population, clinical, patient-generated, and molecular data to generate evidence to personalize cancer care. The ultimate goal is to provide researchers with a complete picture of cancer patients' experiences prior to diagnosis, during treatment, and through long-term survival. This will be accomplished by integrating existing hospital data with state cancer-registry data, insurance claims, and other cancer-related datasets to create a multi-purpose data mart that will serve as a resource for standardized data queries. This work will be performed while continuing to oversee a mature support core for population science activities of the HCCC.

抽象的 爱荷华大学霍顿大学综合癌症中心（HCCC）是NCI资助的综合 癌症中心具有强烈的跨学科合作文化。这是唯一的学术癌症中心 爱荷华州并为农村人口提供独特的环境暴露。人口 研究核心是HCCC共享资源，可为利用临床和 基于人群的工具和数据资源，消除了其使用的障碍。由主任布拉德利博士领导 麦克道尔（McDowell），核心提供流行病学专业知识，研究设计，增强数据共享和分发 使用强大数据促进严格的回顾性和前瞻性研究的准备进行的研究查询 收集和数据策划方法。 麦克道威尔博士在这些领域的专业知识尤其重要，因为我们采用了大数据方法 整合社会，人口，临床，患者生成和分子数据，以生成证据以个性化 癌症护理。最终目标是为研究人员提供癌症患者的完整情况 诊断之前，治疗期间和长期生存之前的经验。这将通过 将现有医院数据与州癌症的数据，保险索赔和其他与癌症有关的数据集成 数据集创建一个多功能数据集市，该集市将作为标准化数据查询的资源。这 将在继续监督对人群科学活动的成熟支持核心的同时，进行工作 HCCC。