Diversity Supplement: Building a Lasting Foundation to Advance Actionable Research on Recovery Support Services for High Risk Individuals with Opioid Use Disorder: The Initiative for JEAP

多样性补充：建立持久的基础，推进阿片类药物使用障碍高风险个体康复支持服务的可行研究：JEAP 倡议

• 批准号: 10704923
• 负责人: Michael R McCart
• 金额: $ 5.05万
• 依托单位: CHESTNUT HEALTH SYSTEMS, INC.
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-06-15 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10704923
• 关键词: Adult; Advocacy; Age; Area; Award; Cause of Death; Collaborations; Communities; Consultations; Dedications; Development; Drug usage; Educational workshop; Effectiveness; Ensure; Equity; Feedback; Foundations; Funding; Goals; Grant; Growth; Health Services Research; Individual; Justice; Lead; Measurement; Mentors; Methods; Mission; Modeling; Opioid; Oregon; Outcome; Overdose; Paper; Persons; Pilot Projects; Policies; Population; Prisons; Probability; Problem-Based Learning; Proliferating; Provider; Public Health; Publishing; R24; Recovery; Recovery Support; Reporting; Research; Research Methodology; Research Personnel; Research Project Grants; Resources; Services; Site; Statistical Data Interpretation; System; Target Populations; Technology; Training; Underrepresented Minority; United States National Institutes of Health; Work; age group; behavior change; career; catalyst; community based participatory research; community based research; design; efficacy study; emerging adult; experience; high risk; high risk population; innovation; medication-assisted treatment; multidisciplinary; opioid use; opioid use disorder; outreach; peer recovery; polysubstance use; preference; programs; recovery services; residence; service providers; skills; social cognitive theory; social learning; stem; tool; undergraduate student

PROJECT SUMMARY/ABSTRACT Two groups that are under-researched but at the highest risk for problems stemming from opioid use disorder are (1) public system-involved emerging adults (EAs; ages 16-25) and (2) individuals who are justice- involved (including EAs). Compared to all other age groups, EAs report the highest rates of drug use, including use of opiates, and public system-involved EAs are more likely to have negative outcomes. For adults of all ages, opioid use results in a 13-fold increased probability of justice system contact. And, among the prison re-entry population, the leading cause of death is overdose, mostly from opioids. Further, polysubstance use is nearly universal for EAs and justice-involved adults (of any age) using opioids. Peer recovery support services and recovery residences are proliferating nationally and may have tremendous benefit for these two high-risk groups, but research on them is limited and lacks scientific rigor. The ultimate goal of this Initiative is rapid advancement of the recovery support services field through developing actionable research such that continued network funding will no longer be necessary to sustain growth. To accomplish this, it is essential to identify and equip investigators willing to dedicate or redirect their research efforts to this topic. However, a fundamental challenge for evaluating recovery support services (and any other community-based program) is the inherent incompatibility of rigorous research methods and the context of real-world services efforts. This requires adaptation or development of innovative and comprehensive methods that thoughtfully combine adaptable designs, advanced measurement, and sophisticated statistical analyses. Investigators also must be competent and well-trained to collaborate with community stakeholders so that rigorous research can be conducted in real- world settings. Optimally, though, people impacted by recovery support services and the research conducted on them must help drive the research agenda; rather than priorities being researcher-initiated, persons in recovery from the target populations and stakeholders in that community (recovery support service providers and payors) must be effectively engaged. Thus, this Initiative is a partnership between advanced researchers, persons in recovery from the target high-risk populations, providers, and payors. The Initiative will advance research on the efficacy/effectiveness of peer recovery supports and recovery residences for public-system involved emerging adults and justice-involved adults with opioid use disorders and medication assisted treatment experience through ambitious but achievable goals: (1) identify priority areas of research via engaging individuals in recovery and providers/payors, (2) grow the field of skilled early career investigators focused on this research, (3) provide seed funds and guidance to produce preliminary studies for NIH funding, and (4) conduct dissemination and outreach to the larger field. With these aims, the Initiative is poised to be a catalyst that provokes rapid expansion in the number of skilled investigators and high-quality research tackling this critical public health issue.

项目摘要/摘要 研究不足的两组，但面临阿片类药物的问题的风险最高 障碍是（1）与公共系统有关的新兴成年人（EAS； 16-25岁）和（2）正义的人 涉及（包括EAS）。与所有其他年龄段相比，EAS报告了吸毒率最高，包括 使用阿片类药物和参与公共系统的EAS更有可能产生负面结果。对于各个年龄段的成年人， 阿片类药物的使用导致司法系统接触的可能性增加了13倍。并且，在监狱中重新进入 人口，死亡的主要原因是用药过量，主要来自阿片类药物。此外，使用多核心几乎是 使用阿片类药物（任何年龄）的EAS和司法成年人普遍。同行恢复支持服务和 恢复住所在全国范围内正在增殖，可能对这两个高风险群体有巨大的好处， 但是对它们的研究是有限的，并且缺乏科学严格。该计划的最终目标是快速发展 通过开发可行的研究，恢复支持服务领域的持续网络 资金将不再需要维持增长。要实现这一目标，必须识别和装备 调查人员愿意将他们的研究工作专注或重定向到该主题。但是，一个基本挑战 评估恢复支持服务（以及任何其他基于社区的计划）是固有的 严格的研究方法不兼容和现实服务工作的背景。这需要 适应性和全面的方法的适应或开发，这些方法有理由结合适应性 设计，高级测量和复杂的统计分析。调查人员还必须有能力 训练有素地与社区利益相关者合作，以便在现实中进行严格的研究 世界环境。但是，最佳的是，受恢复支持服务影响的人们和对 他们必须帮助推动研究议程；而不是优先考虑研究人员康复的人 来自该社区中的目标人群和利益相关者（恢复支持服务提供者和付款人） 必须有效地参与。因此，这项倡议是高级研究人员，人的合作伙伴关系 从目标高风险人群，提供者和付款人中恢复。该倡议将进步 同伴恢复支持和恢复住宅的疗效/有效性涉及新兴 成人和涉及正义的成年人使用阿片类药物使用障碍和药物辅助治疗经验 通过雄心勃勃但可实现的目标：（1）通过让个人参与恢复来确定研究的优先领域 以及提供者/付款人，（2）发展专注于这项研究的熟练早期职业调查人员的领域，（3）提供 种子资金和指导以进行NIH资金进行初步研究，（4）进行传播和 向更大的领域推广。以这些目的，该计划有望成为一种催化剂，促进快速扩张 在熟练的研究人员和高质量研究中，解决了这个关键的公共卫生问题。