Substance Use Scientific Working Group

药物使用科学工作组

• 批准号: 10397173
• 负责人: JOY Marie SCHMITZ
• 金额: $ 19.67万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-04-23 至 2026-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10397173
• 关键词: AIDS prevention; Acquired Immunodeficiency Syndrome; Affect; Alcohols; Area; Basic Science; Biomedical Research; Biostatistics Core; Clinical; Cocaine; Collaborations; Communities; Complex; Development; Emergency department visit; Ensure; Epidemic; Evaluation; Fostering; Funding; Funding Opportunities; Goals; Grant; HIV; Health; Health Sciences; Homeless Youth; Individual; Infrastructure; Institution; International; Lead; Leadership; Link; Marijuana; Medicine; Mental Health; Outcome; Persons; Pilot Projects; Policies; Procedures; Public Health; Research; Research Institute; Research Personnel; Research Project Grants; Research Support; Resources; Risk Factors; School Nursing; Services; Societies; South Texas; Substance Addiction; Substance Use Disorder; Talents; Texas; Universities; Work; addiction; base; college; high risk; improved; innovation; interest; medical schools; member; methamphetamine use; novel; opioid use; overdose death; programs; substance use; substance use treatment; success; transmission process; trend; viral transmission; working group; young adult

PROJECT SUMMARY - SUBSTANCE USE SCIENTIFIC WORKING GROUP The Texas Developmental Center for AIDS Research (D-CFAR) is based at Baylor College of Medicine (Baylor) and University of Texas Health Science Center at Houston (UTHealth) and the Texas Biomedical Research Institute (TxBiomed) in San Antonio. It will establish a Substance Use Scientific Working Group (SU- SWG). Substance use trends in the state of Texas are similar to the nation as a whole in showing an increase in opioid use and related emergency department visits and overdose deaths in recent years. Equally concerning are recent trends in the use of methamphetamine, marijuana, cocaine, and alcohol. Substance use and HIV are inextricably linked. Substance use is a well-established risk factor for transmission of the virus. For people living with HIV, substance use and addiction can hasten the progression of HIV and its consequences. Despite its significant impact on HIV, the intersection of substance use and HIV has been an underdeveloped research area, especially in areas of the US with weaker substance use treatment infrastructures like Texas. The proposed Texas D-CFAR SU-SWG will foster a robust research program in three areas that align with the proposed D-CFAR to fill this gap: 1) substance use as a co-factor for transmission of HIV; 2) impact of substance use on progression of HIV and its consequences; 3) novel treatment approaches for HIV prevention and treatment for individuals who use substances. The SU-SWG will support research in these areas by developing key resources, services, pilot funding opportunities, and by fostering discussions and collaborations between Texas D-CFAR members. To achieve its goals, the SU-SWG will: 1) Work with the proposed Cores and Core services to develop and support substance use as a critical area of research focus for ending HIV and optimizing HIV health in Texas. 2) Inform the Texas D-CFAR community about ongoing and future research on the intersection of substance use and HIV, both at our D-CFAR, nationally, and internationally. 3) Inform the D-CFAR community about external funding opportunities on substance use, provide pilot project funding opportunities through the Developmental Core, and catalyze collaborations. 4) Expand the SU-SWG by opening membership to substance use and HIV researchers and trainees at other Texas institutions. To achieve these aims, the D-CFAR has assembled a group of established and early stage investigators in both HIV and substance use to bring together in the SU-SWG to foster research in the intersection of these two epidemics. The SU-SWG includes persons with deep connections to the community and local public health officials as well as academicians who have developed and lead innovative programs to deliver substance use treatments. The SU-SWG leadership, in collaboration with the D-CFAR leadership, has identified a comprehensive 5-year action plan, set of activities, policies and procedures and evaluation metrics to ensure success. This activity organized by the SU-SWG will accelerate efforts to end HIV and improve the health of people with HIV in Texas and beyond.

项目摘要 - 药物使用科学工作组 德克萨斯州艾滋病研究中心（D-CFAR）位于贝勒医学院 （贝勒）和德克萨斯大学健康科学中心（Uthealth）和德克萨斯州生物医学 圣安东尼奥的研究所（TXBIOMED）。它将建立一个药物使用科学工作组（su- SWG）。德克萨斯州的药物使用趋势与整个国家相似，显示出增长 近年来，阿片类药物使用及相关急诊就诊和过量死亡。同样 关于甲基苯丙胺，大麻，可卡因和酒精的使用趋势是最近的趋势。使用物质 和艾滋病毒是密不可分的。使用物质是传播病毒的危险因素。为了 患有艾滋病毒，吸毒和成瘾的人可以加快艾滋病毒的进展及其后果。 尽管对艾滋病毒的影响很大，但物质使用和艾滋病毒的交集一直是不发达的 研究领域，尤其是在美国较弱的药物使用治疗基础设施等美国地区。 拟议的德克萨斯州D-CFAR SU-SWG将在与与该领域保持一致的三个领域的强大研究计划 提议的D-CFAR填补了这一空白：1）物质用作艾滋病毒传播的共同因素； 2）的影响 艾滋病毒进展及其后果的物质使用； 3）预防HIV的新型治疗方法 和使用使用物质的人的治疗。 SU-SWG将支持这些领域的研究 开发关键资源，服务，试点资金机会，并通过促进讨论和协作 在德克萨斯州D-CFAR成员之间。为了实现其目标，SU-SWG将：1）与拟议的核心合作 以及开发和支持物质使用的核心服务，作为结束HIV的研究重点的关键领域 并在德克萨斯州优化艾滋病毒健康。 2）通知德克萨斯州D-CFAR社区正在进行的和未来 在我们的D-CFAR，国内和国际上，有关物质使用和艾滋病毒交集的研究。 3） 告知D-CFAR社区有关药物使用的外部资金机会，提供试点项目 通过发展核心资助机会，并催化合作。 4）扩展SU-SWG 通过开放其他得克萨斯州其他机构的药物使用和艾滋病毒研究人员和学员的会员资格。到 达到这些目标，D-CFAR已组建了一群已建立和早期的调查员 艾滋病毒和物质用来将SU-SWG聚集在一起，以促进这两个交集 流行病。 SU-SWG包括与社区和当地公共卫生有深厚联系的人 官员以及已经制定并领导创新计划来提供药物使用的院士 治疗。 SU-SWG领导与D-CFAR领导合作，已经确定了 全面的5年行动计划，一组活动，政策和程序以及评估指标，以确保 成功。 SU-SWG组织的这项活动将加速努力结束艾滋病毒并改善 德克萨斯州及以后的艾滋病毒的人。