Administrative Core

行政核心

基本信息

批准号：
10375505
负责人：
David A Rasko
金额：
$ 51.21万
依托单位：
UNIVERSITY OF MARYLAND BALTIMORE
依托单位国家：
美国
项目类别：
财政年份：
2014
资助国家：
美国
起止时间：
2014-04-15 至 2024-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10375505
关键词：
Accountability Administrator Advanced Development Bacteria Communicable Diseases Communication Communities Consultations Contracts Data Disease Outcome Disease Vectors Education and Outreach Educational workshop Funding Funding Mechanisms Future Genomic Centers for Infectious Diseases Genomics Goals Grant Human Microbiome Human Resources Infection Infrastructure Investigation Laboratories Leadership Maryland Monitor Morbidity - disease rate National Institute of Allergy and Infectious Disease Nucleic acid sequencing Peer Review Pilot Projects Postdoctoral Fellow Productivity Publications Reporting Research Research Priority Research Project Grants Resource Allocation Schedule Technology Telephone Time TimeLine Training Training Activity Universities Viral Work base benefit sharing co-infection data dissemination data management experience graduate student innovation interest medical schools meetings member mortality new technology new therapeutic target pathogen programs success web site

项目摘要

Through the activities in this Administrative Core, we will provide scientific and administrative leadership and oversight for this highly collaborative U19 proposal that will deploy multiple genomics-enabled approaches to investigate viral, bacteria fungal, and parasitic pathogens associated with high mortality and morbidity, analyze co-infections that may alter disease outcome, and emphasize the identification of novel drug targets for those infections that are difficult to treat. The components of this GCID will include four interacting Research Projects that will make use of our state-of-the-art Technology and Data Management and Dissemination Cores. To support these integrated activities we will (i) establish an Executive Committee that will be responsible for overall scientific direction and progress of all Research Projects and Cores, (ii) provide general administrative support and fiscal accountability at the level of each Research Project and Core, (iii) establish mechanisms for regular communication with NIAID, the external Steering Committee, and the other GCIDs, (iv) engage in outreach and training activities in order to transfer genomics expertise from our GCID to the infectious disease community, and (v) in consultation with NIAID, establish a mechanism for funding Collaborative Pilot Projects across GCIDs that will further advance the development of novel technologies or explore high-priority research topics in infectious disease.

通过该行政核心的活动，我们将提供科学和行政领导以及对这项高度协作的 U19 提案的监督，该提案将部署多种基因组学方法研究与高死亡率和发病率相关的病毒、细菌、真菌和寄生病原体，分析可能改变疾病结果的合并感染，并强调为这些感染确定新的药物靶点难以治疗的感染。该 GCID 的组成部分将包括四个相互作用的研究项目这将利用我们最先进的技术、数据管理和传播核心。到支持这些综合活动，我们将 (i) 建立一个执行委员会，负责所有研究项目和核心的总体科学方向和进展，(ii) 提供一般管理每个研究项目和核心层面的支持和财政责任，(iii) 建立机制与 NIAID、外部指导委员会和其他 GCID 定期沟通，(iv) 参与外展和培训活动，以便将我们的 GCID 的基因组学专业知识转移到传染病领域 (v) 与 NIAID 协商，建立资助合作试点项目的机制跨 GCID 将进一步推动新技术的开发或探索高优先级研究传染病主题。