Mwanza-Tanzania Research Training Program in HIV Clinical Investigation

姆万扎-坦桑尼亚艾滋病毒临床研究研究培训项目

基本信息

批准号：
10374941
负责人：
Daniel W Fitzgerald
金额：
$ 30万
依托单位：
WEILL MEDICAL COLL OF CORNELL UNIV
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-04-01 至 2026-03-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10374941
关键词：
AIDS prevention Africa Appointment Area Behavioral Research Cardiovascular Diseases Caring Clinical Investigator Clinical Trials Collaborations Doctor of Pharmacy Doctor of Philosophy Funding Goals HIV HIV Infections Human immunodeficiency virus test Hygiene Institutes Institution Intervention Studies Intervention Trial Investigation London Medical Research Outcome Patients Phase Physicians Postdoctoral Fellow Preparation Prevention Research Research Research Project Grants Research Training Schools Scientist Tanzania Training Training Programs Tropical Medicine United States National Institutes of Health Vaccine Research Women&apos s Health clinical investigation co-infection epidemiology study improved individual patient institutional capacity medical schools patient oriented patient oriented research pragmatic trial prevent programs

项目摘要

The program will strengthen patient-oriented HIV clinical investigation training of physician-scientists and other exceptional clinicians in Mwanza, in northwestern Tanzania. The program builds upon two decades of collaboration and capacity building by the partner institutions. The primary research institution in Tanzania will be the Mwanza Intervention Trials Unit (MITU), which is a unit of Tanzania’s National Institute for Medical Research (NIMR). MITU was established in 2006 as a collaboration between NIMR and the London School of Hygiene and Tropical Medicine (LSHTM) to strengthen HIV interventional research in Tanzania. MITU collaborates closely with the Weill Bugando School of Medicine, which is also located in Mwanza. Weill Bugando was established in 2003 to train physicians for northwestern Tanzania. MITU and Weill Bugando have collaborated with Weill Cornell Medical College since their founding. This research training program aims to fill a critical gap in Mwanza: the need for Tanzanian physicians with rigorous training in patient-oriented HIV clinical investigation. We use the NIH definition of clinical investigation as research which directly interacts with individual patients or clusters of patients in Phase I, II, or III clinical trials, pragmatic trials, or formative epidemiologic or behavioral research in preparation for clinical trials. The goals of the proposed training program are: 1.To increase the number of clinical investigators at MITU and thereby increase institutional capacity for HIV clinical investigation 2. Establish Weill Bugando/MITU as a sustainable training center for HIV clinical investigation. The ultimate goal is to prevent new HIV infections, provide effective HIV care, and improve HIV outcomes in Tanzania and East Africa. We will provide long-term training to fifteen outstanding clinician scientists to conduct patient-oriented HIV clinical investigation. We will primarily train physicians but will also train exceptional other clinicians (PharmD, DMD). We will train 10 PhDs, and 5 MS degree candidates. Tanzanian trainees will benefit from participation in 17 active research projects in five synergistic areas of HIV investigation including HIV prevention and vaccine research, implementation of HIV testing and treatment, women’s health, HIV related co-infections, and HIV and cardiovascular disease. We will also strengthen the PhD program in clinical investigation at Weill Bugando by introducing 4 new graduate courses in clinical investigation. Weill Cornell is committing institutional funds so that 4 of the best PhD graduates can have 2-year post-doctoral appointments as MITU research scientists after their Fogarty training. At the end of the 5-year training program, MITU will have a cadre of clinical investigators and a greater depth and breadth of externally funded HIV patient-oriented research. MITU/Weill Bugando will be a training hub for HIV clinical investigators in East Africa.

该计划将加强对身体科学家和坦桑尼亚西北部Mwanza的其他杰出临床医生。该计划建立在二十年的合作机构的协作和能力建设。坦桑尼亚的主要研究机构将成为Mwanza干预试验部（MITU），该单位是坦桑尼亚国家医学研究所的单位研究（NIMR）。 MITU成立于2006年，是NIMR与伦敦学校之间的合作卫生和热带医学（LSHTM），以加强坦桑尼亚的HIV介入研究。 mitu 与位于Mwanza的Weill Bugando医学院密切合作。威尔 Bugando成立于2003年，旨在培训坦桑尼亚西北部的医生。 Mitu和Weill Bugando 自成立以来，Weill Cornell医学院就与Weill Cornell医学院合作。该研究培训计划旨在填补Mwanza的关键空白：坦桑尼亚医生的需求对以患者为导向的HIV临床研究进行了严格的培训。我们使用NIH的临床定义研究作为直接与单个患者或患者群体相互作用的研究 III临床试验，务实试验或形成性流行病学或行为研究，以准备临床试验。拟议培训计划的目标是：1。增加临床研究人员的数量 MITU，从而提高了HIV临床调查的机构能力2。建立Weill Bugando/Mitu 作为艾滋病毒临床调查的可持续培训中心。最终目标是防止新的艾滋病毒感染，提供有效的艾滋病毒护理并改善坦桑尼亚和东非的艾滋病毒结局。我们将为15位出色的临床科学家提供长期培训，以进行以患者为导向的HIV 临床研究。我们将培训医师，但也将培训其他临床医生（PharmD， DMD）。我们将培训10个博士学位和5毫秒的候选人。坦桑尼亚学员将受益于参与在艾滋病毒调查的五个协同领域的17个活跃研究项目中，包括艾滋病毒预防和疫苗研究，艾滋病毒测试和治疗的实施，妇女健康，与艾滋病毒相关的共同感染以及艾滋病毒和心血管疾病。我们还将在Weill的临床研究中加强博士学位计划 Bugando通过引入4个新的研究生课程进行临床研究。威尔·康奈尔（Weill Cornell）正在犯下机构资金使得4位最好的博士学位毕业生可以在两年期间任命为2年 MITU研究科学家在他们的Fogarty培训后。在5年培训计划结束时，MITU将有临床研究人员的干部以及外部资助的HIV患者的深度和广度研究。 MITU/Weill Bugando将成为东非艾滋病毒临床研究人员的培训中心。